Search Results - "da Silva, Gilnei Bruno"

Curcumin promotes apoptosis of human melanoma cells by caspase 3 by Manica, Daiane, Silva, Gilnei Bruno da, Silva, Alana Patrícia da, Marafon, Filomena, Maciel, Sarah Franco Vieira de Oliveira, Bagatini, Margarete Dulce, Moreno, Marcelo

“…Cutaneous melanoma (CM) is a malignant neoplasm with a high metastatic rate that shows poor response to systemic treatments in patients with advanced stages…”
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Chemical profile and biological properties of the Piper corcovadense C.DC. essential oil by Henrique Fontoura, Bruno, Cristina Perin, Ellen, Paula Buratto, Ana, Francisco Schreiner, Jucemar, Menezes Cavalcante, Kamyla, Dias Teixeira, Sirlei, Manica, Daiane, Antônio Narzetti, Rafael, Bruno da Silva, Gilnei, Dulce Bagatini, Margarete, Luiza Cadorin Oldoni, Tatiane, Teresinha Carpes, Solange

“…The essential oil fromPiper corcovadense D.DC. (EOPc), an important plant belonging to the Piperaceae family, which is commonly found in the northern region of…”
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Rosmarinic acid decreases viability, inhibits migration and modulates expression of apoptosis-related CASP8/CASP3/NLRP3 genes in human metastatic melanoma cells by da Silva, Gilnei Bruno, Manica, Daiane, da Silva, Alana Patrícia, Marafon, Filomena, Moreno, Marcelo, Bagatini, Margarete Dulce

“…Cutaneous melanoma is the most aggressive type of skin cancer; it is difficult to treat, and has been highlighted in recent years due to increasing numbers of…”
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Novel possibility for cutaneous melanoma treatment by means of rosmarinic acid action on purinergic signaling by da Silva, Gilnei Bruno, Yamauchi, Milena Ayumi, Zanini, Daniela, Bagatini, Margarete Dulce

“…Cancer cases have increased significantly in Brazil and worldwide, with cutaneous melanoma (CM) being responsible for nearly 57,000 deaths in the world. Thus,…”
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High levels of extracellular ATP lead to different inflammatory responses in COVID-19 patients according to the severity by da Silva, Gilnei Bruno, Manica, Daiane, da Silva, Alana Patrícia, Kosvoski, Greicy Cristine, Hanauer, Marceli, Assmann, Charles Elias, Simões, Júlia Leão Batista, Pillat, Micheli Mainardi, de Lara, Jéssica Dotto, Marafon, Filomena, Bertollo, Amanda Gollo, Mingoti, Maiqueli E. D., Gavioli, Jullye, Réus, Gislaine Zilli, de Oliveira, Gabriela Gonçalves, Ignácio, Zuleide Maria, Bagatini, Margarete Dulce

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has significantly impacted the world and has driven many researchers into the…”
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Extract of Araçá-Boi and Its Major Phenolic Compound, Trans-Cinnamic Acid, Reduce Viability and Inhibit Migration of Human Metastatic Melanoma Cells by Borsoi, Felipe Tecchio, da Silva, Gilnei Bruno, Manica, Daiane, Bagatini, Margarete Dulce, Pastore, Glaucia Maria, Arruda, Henrique Silvano

“…Cutaneous melanoma is an aggressive type of skin cancer that is recognized for its high metastatic potential and the challenges it presents in its treatment…”
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Caffeine reduces viability, induces apoptosis, inhibits migration and modulates the CD39/CD73 axis in metastatic cutaneous melanoma cells by Manica, Daiane, da Silva, Gilnei Bruno, de Lima, Jussara, Cassol, Joana, Dallagnol, Paula, Narzetti, Rafael Antônio, Moreno, Marcelo, Bagatini, Margarete Dulce

“…We aimed to evaluate the effect of caffeine on viability, apoptosis, migration, redox profile and modulatory effect of the purinergic system of cutaneous…”
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Implications of COVID-19 in Parkinson’s disease: the purinergic system in a therapeutic-target perspective to diminish neurodegeneration by Simões, Júlia Leão Batista, de Carvalho Braga, Geórgia, Eichler, Samantha Webler, da Silva, Gilnei Bruno, Bagatini, Margarete Dulce

“…The pathophysiology of Parkinson’s disease (PD) is marked by degeneration of dopaminergic neurons in the substantia nigra. With advent of COVID-19, which is…”
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Evaluation of the effects of metformin on antioxidant biomarkers and mineral levels in patients with type II diabetes mellitus: A cross-sectional study by Manica, Daiane, Sandri, Gabriela, da Silva, Gilnei Bruno, Manica, Aline, da Silva Rosa Bonadiman, Beatriz, dos Santos, Daniel, Flores, Érico Marlon Moraes, Bolzan, Rodrigo Cordeiro, Barcelos, Raquel Cristine Silva, Tomazoni, Fernanda, Suthovski, Gabriela, Bagatini, Margarete Dulce, Benvegnú, Dalila Moter

“…Diabetes mellitus (DM) and arterial hypertension are considered serious public health problems. Several studies have shown that oxidative stress is usually…”
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Oxidative stress in Hashimoto’s thyroiditis: possible adjuvant therapies to attenuate deleterious effects by da Silva, Gilnei Bruno, Yamauchi, Milena Ayumi, Bagatini, Margarete Dulce

“…A number of studies have shown that oxidative stress is related to the pathogenesis of several immunological diseases, such as Hashimoto’s thyroiditis (HT),…”
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Cytokine storm in human monkeypox: A possible involvement of purinergic signaling by da Silva, Gilnei Bruno, de Carvalho Braga, Geórgia, Simões, Júlia Leão Batista, Kempka, Aniela Pinto, Bagatini, Margarete Dulce

“…•Evidence indicates that a cytokine storm is involved in the pathophysiology of monkeypox.•We hypothesize that purinergic signaling plays a role in the…”
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Extraction, characterization, and antineoplastic effect of Macadamia nut extracts against cutaneous melanoma cells: a comprehensive study focused on SK-MEL-28 cells by Amarante, Bruno Antônio, Saccomori, Eduardo, Biancini, Mateus Biazus, Zanella, Odivan, Bilibio, Denise, Bender, João Paulo, da Silva, Gilnei Bruno, Manica, Daiane, Bagatini, Margarete Dulce, Bruno, Alessandra Nejar, Priamo, Wagner Luiz

“…[Display omitted] •Macadamia nut extracts obtained from ultrasound-assisted extraction and pressurized ethanol.•Global yield and fatty acids composition were…”
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Hydroalcoholic Extract of Centella asiatica and Madecassic Acid Reverse Depressive-Like Behaviors, Inflammation and Oxidative Stress in Adult Rats Submitted to Stress in Early Life by Bertollo, Amanda Gollo, Mingoti, Maiqueli Eduarda Dama, de Medeiros, Jesiel, da Silva, Gilnei Bruno, Capoani, Giovana Tamara, Lindemann, Heloisa, Cassol, Joana, Manica, Daiane, de Oliveira, Tacio, Garcez, Michelle Lima, Bagatini, Margarete Dulce, Bohnen, Lilian Caroline, Junior, Walter Antônio Roman, Ignácio, Zuleide Maria

“…Major depressive disorder (MDD) is a severe disorder that causes enormous loss of quality of life, and among the factors underlying MDD is stress in maternal…”
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Phytotherapeutic potential of Campomanesia xanthocarpa (Mart.) O. Berg: antitumor effects in vitro and in silico, with emphasis on SK-MEL-28 melanoma cells—a study on leaf and fruit infusions by da Silva, Vanessa Ruana Ferreira, da Silva, Gilnei Bruno, Manica, Daiane, Deolindo, Carolina Turnes Pasini, Bagatini, Margarete Dulce, Kempka, Aniela Pinto

“…The study investigated the efficacy of Campomanesia xanthocarpa infusions on human melanoma cells (SK-MEL-28). The phytochemical profile revealed 18 phenolic…”
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Curcumin modulates purinergic signaling and inflammatory response in cutaneous metastatic melanoma cells by Manica, Daiane, da Silva, Gilnei Bruno, Narzetti, Rafael Antônio, Dallagnoll, Paula, da Silva, Alana Patrícia, Marafon, Filomena, Cassol, Joana, de Souza Matias, Letícia, Zamoner, Ariane, de Oliveira Maciel, Sarah Franco Vieira, Moreno, Marcelo, Bagatini, Margarete Dulce

“…Cutaneous melanoma (CM) poses a therapeutic challenge due to its aggressive nature and often limited response to conventional treatments. Exploring novel…”
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Aqueous extracts of Physalis peruviana L. fruit promote apoptosis by overexpression of caspases 9/3 and balancing the redox profile of cutaneous melanoma cells by da Silva, Alana Patrícia, da Silva, Gilnei Bruno, Manica, Daiane, Marafon, Filomena, Narzetti, Rafael Antonio, Dallagnol, Paula, Matias, Letícia de Souza, Gavioli, Jullye, Kosvoski, Greicy Cristine, De Rocco Donassolo, Sabine, da Luz, Francielle do Rocio, de Carvalho, Gilbrair Paulo, Zamoner Pacheco de Souza, Ariane, Giacobbo, Clevison Luiz, Bender, João Paulo, Fogolari, Odinei, Tormen, Luciano, Bagatini, Margarete Dulce

“…•Maturation stage of PP fruits influences in phenolic contents and antioxidants.•Aqueous extracts of PP fruit promote apoptosis in melanoma cells by caspases 9…”
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