Search Results - "da Silva, Claudio Antonio"
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The effects of Phα1β, a spider toxin, calcium channel blocker, in a mouse fibromyalgia model
Published in Toxicon (Oxford) (01-04-2014)“…This study investigated the effects of Phα1β, pregabalin and diclofenac using an animal model of fibromyalgia (FM). Repeated administration of reserpine…”
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2
Chemical composition and free radical scavenging activity of pollen loads from stingless bee Melipona subnitida Ducke
Published in Journal of food composition and analysis (01-09-2006)“…Bee-collected pollen (“bee pollen”) is promoted as a health food with a wide range of nutritional and therapeutic properties. In order to evaluate the chemical…”
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Current Drug Development Overview: Targeting Voltage-Gated Calcium Channels for the Treatment of Pain
Published in International journal of molecular sciences (25-05-2023)“…Voltage-gated calcium channels (VGCCs) are targeted to treat pain conditions. Since the discovery of their relation to pain processing control, they are…”
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The effects of Ph alpha 1 beta , a spider toxin, calcium channel blocker, in a mouse fibromyalgia model
Published in Toxicon (Oxford) (01-04-2014)“…This study investigated the effects of Ph alpha 1 beta , pregabalin and diclofenac using an animal model of fibromyalgia (FM). Repeated administration of…”
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5
Application of the UV–vis spectrophotometry method for the determination of glutamate in the cerebrospinal fluid of rats
Published in Journal of pharmaceutical and biomedical analysis (15-07-2020)“…•Spectrophotometry of CSF glutamate levels is reliable.•More sustainable method for CSF glutamate dosing.•Useful for academic research detection. In…”
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Development of solid dispersions of β-lapachone in PEG and PVP by solvent evaporation method
Published in Drug development and industrial pharmacy (04-05-2018)“…β-lapachone (βlap) has shown potential use in various medical applications. However, its poor solubility has limited its systemic administration and clinical…”
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Calcium channels blockers toxins attenuate abdominal hyperalgesia and inflammatory response associated with the cerulein-induced acute pancreatitis in rats
Published in European journal of pharmacology (15-01-2021)“…Agents that modulate the activity of high-voltage gated calcium channels (HVCCs) exhibit experimentally and clinically significant effect by relieving visceral…”
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Solid dispersion of β-lapachone in PVP K30 and PEG 6000 by spray drying technique
Published in Journal of thermal analysis and calorimetry (01-12-2021)“…Beta-lapachone (βlap) is a naphthoquinone derived from Lapachol, a substance extracted from the Bignoniaceae family of trees, genus Tabebuia; found in the…”
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PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina
Published in Toxins (11-03-2016)“…The in vivo neuroprotective effect of PhTx3-4, a spider toxin N-P/Q calcium channel blocker, was studied in a rat model of NMDA-induced injury of the retina…”
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Analgesic effects of the CTK 01512-2 toxin in different models of orofacial pain in rats
Published in Pharmacological reports (01-06-2020)“…Orofacial pain is clinically challenging, having therapeutic failures and side effects. This study evaluated the antinociceptive activities of the CTK 01512-2…”
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Aplysfistularine: a novel dibromotyrosine derivative isolated from Aplysina fistularis
Published in Química Nova (2012)“…The new dibromotyrosine derivative 3,5-dibromo-4-[3'dimethylamonium]propoxyphenyl]-N,N,N-trimethylethanamonium, here referred to as aplysfistularine (1), was…”
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Neolignans from Licaria chrysophylla and Licaria aurea with DNA topoisomerase II-α inhibitory activity
Published in Química Nova (2012)“…Seven natural neolignans isolated from Licaria chrysophylla and Licaria aurea along with five semisynthetic derivatives were tested for their inhibitory action…”
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Phaeophytins from Thyrsacanthus ramosissimus Moric. with inhibitory activity on human dna topoisomerase II-α
Published in Química Nova (2012)“…Our study reports the extraction and isolation of a new phaeophytin derivative 15¹-hydroxy-(15¹-S)-porphyrinolactone, designated anamariaine (1) herein,…”
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The inhibitory effect of Phα1β toxin on diabetic neuropathic pain involves the CXCR4 chemokine receptor
Published in Pharmacological reports (01-02-2020)“…Diabetic neuropathy is a common cause of painful diabetic neuropathy (PDN). C-X-C chemokine receptor type 4 (CXCR4) expression is increased in peripheral nerve…”
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A ciberinformatização das fronteiras em espaços da contracultura
Published in Texto digital (Florianópolis, SC, Brasil) (03-09-2024)“…Este artigo aborda os espaços fronteiriços entre o livro Anos 70 Bahia, de Luiz Afonso e Sérgio Siqueira (2017), e o documentário Malucos de Estrada – Parte II…”
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Solid dispersion of [beta]-lapachone in PVP K30 and PEG 6000 by spray drying technique
Published in Journal of thermal analysis and calorimetry (01-12-2021)“…Beta-lapachone ([beta]lap) is a naphthoquinone derived from Lapachol, a substance extracted from the Bignoniaceae family of trees, genus Tabebuia; found in the…”
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Constituintes químicos e atividade antioxidante de Sida galheirensiS Ulbr. (Malvaceae)
Published in Química Nova (01-12-2006)“…The phytochemical investigation of Sida galheirensis led to the isolation of 5,4'-dihydroxy-3,7,3´-trimethoxyflavone, 17³-ethoxyphaeoforbide, a rare natural…”
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