Search Results - "da Silva, Andréa Alice"
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Cathepsin B and Plasma Kallikrein Are Reliable Biomarkers to Discriminate Clinically Significant Hepatic Fibrosis in Patients with Chronic Hepatitis-C Infection
Published in Microorganisms (Basel) (01-09-2022)“…We aimed to determine the biomarker performance of the proteolytic enzymes cathepsin B (Cat B) and plasma kallikrein (PKa) and transforming growth factor…”
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Chronic Trypanosoma Cruzi -Elicited Cardiomyopathy: From the Discovery to the Proposal of Rational Therapeutic Interventions Targeting Cell Adhesion Molecules and Chemokine Receptors - How to Make a Dream Come True
Published in Memórias do Instituto Oswaldo Cruz (01-07-2009)“…One hundred years ago, Carlos Chagas discovered a new disease, the American trypanosomiasis. Chagas and co-workers later characterised the disease's common…”
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Serum ferritin at admission in hospitalized COVID-19 patients as a predictor of mortality
Published in The Brazilian journal of infectious diseases (01-03-2021)“…Some COVID-19 patients have higher mortality and the responsible factors for this unfavorable outcome is still not well understood. To study the association…”
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Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the nervous tissue
Published in PloS one (05-01-2021)“…Memory impairment has been associated with chronic Chagas disease (CD), a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. In…”
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Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease
Published in Memórias do Instituto Oswaldo Cruz (01-06-2014)“…Heart tissue inflammation, progressive fibrosis and electrocardiographic alterations occur in approximately 30% of patients infected by Trypanosoma cruzi,…”
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Evaluation of herpesvirus members on hospital admission in patients with systemic lupus erythematous shows higher frequency of Epstein-Barr virus and its associated renal dysfunction
Published in Brazilian Journal of Nephrology (01-10-2022)“…Members of the Herpesviridae family have been described in patients with systemic lupus erythematous (SLE), but the clinical impact on renal function is not…”
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AVALIAÇÃO DO STATUS SOROLÓGICO VACINAL CONTRA SARAMPO, RUBÉOLA E FEBRE AMARELA EM CRIANÇAS EXPOSTAS VERTICALMENTE AO VÍRUS ZIKA
Published in The Brazilian journal of infectious diseases (01-01-2022)“…Quase 6 milhões de crianças com até 5 anos morreram em 2015 (UNICEF), mais da metade por doenças infecciosas evitáveis pela vacinação. Outras enfermidades…”
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AVALIAÇÃO DO STATUS SOROLÓGICO VACINAL CONTRA SARAMPO, RUBÉOLA E FEBRE AMARELA EM CRIANÇAS EXPOSTAS VERTICALMENTE AO VÍRUS ZIKA
Published in The Brazilian journal of infectious diseases (01-01-2022)“…Quase 6 milhões de crianças com até 5 anos morreram em 2015 (UNICEF), mais da metade por doenças infecciosas evitáveis pela vacinação. Outras enfermidades…”
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ANÁLISE DA FREQUÊNCIA DE COINFECÇÕES POR SARS-COV-2 E DENV E AVALIAÇÃO DA GRAVIDADE DAS COINFECÇÕES EM RELAÇÃO ÀS MONOINFECÇÕES
Published in The Brazilian journal of infectious diseases (01-01-2022)“…Paralelo à pandemia de COVID-19, Brasil continuou a enfrentar doenças tropicais como a Dengue. Mas, segundo os Boletins Epidemiológicos, os casos de Dengue no…”
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TNF/TNFR1 signaling up-regulates CCR5 expression by CD8 + T lymphocytes and promotes heart tissue damage during Trypanosoma cruzi infection: beneficial effects of TNF-α blockade
Published in Memórias do Instituto Oswaldo Cruz (01-06-2008)“…In Chagas disease, understanding how the immune response controls parasite growth but also leads to heart damage may provide insight into the design of new…”
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CD64 expression on polymorphonuclear cells as a potential marker for monitoring the human cytomegalovirus replication after kidney transplantation
Published in Jornal brasileiro de patologia e medicina laboratorial (01-04-2017)“…ABSTRACT Human cytomegalovirus (HCMV) infection is the main cause of morbidity in kidney transplant recipients. This study aims to investigate if CD64…”
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A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy
Published in PLoS pathogens (01-01-2015)“…Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a prototypical neglected tropical disease. Specific immunity promotes acute phase survival…”
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The beneficial effect of fluoxetine on behavioral and cognitive changes in chronic experimental Chagas disease unveils the role of serotonin fueling astrocyte infection by Trypanosoma cruzi
Published in PLoS neglected tropical diseases (01-05-2024)“…In Chagas disease (CD), a neglected tropical disease caused by the parasite Trypanosoma cruzi, the development of mental disorders such as anxiety, depression,…”
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Trypanosoma cruzi -induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions
Published in Brain, behavior, and immunity (01-10-2012)“…Highlight ► Trypanosoma cruzi induces depressive-like behavior independently of meningoencephalitis but responsive to tripanocide drug and TNF-targeting…”
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Genetic Polymorphism at CCL5 Is Associated With Protection in Chagas' Heart Disease: Antagonistic Participation of CCR1 + and CCR5 + Cells in Chronic Chagasic Cardiomyopathy
Published in Frontiers in immunology (11-04-2018)“…Chronic cardiomyopathy is the main clinical manifestation of Chagas disease (CD), a disease caused by infection. A hallmark of chronic chagasic cardiomyopathy…”
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Achados bucais e laboratoriais em pacientes com lúpus eritematoso sistêmico
Published in Jornal brasileiro de patologia e medicina laboratorial (01-12-2010)“…INTRODUÇÃO: O lúpus eritematoso sistêmico (LES) é uma doença inflamatória crônica caracterizada por manifestações clínicas variadas. Os poucos trabalhos…”
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Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury
Published in PLoS neglected tropical diseases (01-05-2012)“…The factors contributing to chronic Chagas' heart disease remain unknown. High nitric oxide (NO) levels have been shown to be associated with cardiomyopathy…”
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Perforin-expressing cytotoxic cells contribute to chronic cardiomyopathy in Trypanosoma cruzi infection
Published in International journal of experimental pathology (01-02-2010)“…Summary Understanding the dual participation of the immune response in controlling the invader and at the same time causing tissue damage might contribute to…”
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P8.142: Perturbations in Podocyte Transcriptome and Biological Pathways Induced by Injury Caused by FSGS Associated Circulating Factors
Published in Transplantation (01-09-2022)Get full text
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