Search Results - "da S M Forezi, Luana"
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Bioactive 1,2,3‐Triazoles: An Account on their Synthesis, Structural Diversity and Biological Applications
Published in Chemical record (01-10-2021)“…The triazole heterocycle is a privileged scaffold in medicinal chemistry, since its structure is present in a large number of biologically active molecules,…”
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Chemoselective Synthesis of Mannich Adducts from 1,4-Naphthoquinones and Profile as Autophagic Inducers in Oral Squamous Cell Carcinoma
Published in Molecules (Basel, Switzerland) (30-12-2022)“…Oral squamous cell carcinoma (OSCC) is a worldwide public health problem, accounting for approximately 90% of all oral cancers, and is the eighth most common…”
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3
1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis
Published in Beilstein journal of organic chemistry (2022)“…Several low molecular weight naphthoquinones are very useful in organic synthesis. These compounds have given rise to thousands of other naphthoquinones that…”
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Supramolecular Catalysts for Organic Synthesis: Preparation and Applications of Cyclodextrins and Calixarenes in C−C Cross‐Coupling Reactions
Published in European journal of organic chemistry (20-09-2022)“…Reactions that promote the formation of carbon–carbon bonds are of great importance in organic synthesis, since they transform available, relatively…”
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5
Menadione: a platform and a target to valuable compounds synthesis
Published in Beilstein journal of organic chemistry (11-04-2022)“…Naphthoquinones are important natural or synthetic compounds belonging to the general class of quinones. Many compounds in this class have become drugs that…”
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6
Carbene Transfer Reactions Catalysed by Dyes of the Metalloporphyrin Group
Published in Molecules (Basel, Switzerland) (29-03-2018)“…Carbene transfer reactions are very important transformations in organic synthesis, allowing the generation of structurally challenging products by catalysed…”
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7
Alternative Routes to the Click Method for the Synthesis of 1,2,3-Triazoles, an Important Heterocycle in Medicinal Chemistry
Published in Current topics in medicinal chemistry (01-01-2018)“…Heterocyclic rings having nitrogen atoms are the molecular fragments most used in drug design by using the tools of medicinal chemistry. The 1,2,4-triazole…”
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8
Study on the regioselectivity of the N-ethylation reaction of N -benzyl-4-oxo-1,4-dihydroquinoline-3-carboxamide
Published in Beilstein journal of organic chemistry (12-02-2019)“…4-Oxoquinolines are a class of organic substances of great importance in medicinal chemistry, due to their biological and synthetic versatility…”
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Novel naphthoquinone-1H-1,2,3-triazole hybrids: Design, synthesis and evaluation as inductors of ROS-mediated apoptosis in the MCF-7 cells
Published in Bioorganic & medicinal chemistry (15-03-2024)“…[Display omitted] •New twenty-three hybrids bisnaphthoquinone x 1,2,3-1H-triazole were developed.•All compounds were screened against breast cancer cell lines…”
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Design, synthesis, in vitro and in silico studies of novel 4-oxoquinoline ribonucleoside derivatives as HIV-1 reverse transcriptase inhibitors
Published in European journal of medicinal chemistry (15-05-2020)“…Human immunodeficiency virus type 1 (HIV-1) is a public health problem that affects over 38 million people worldwide. Although there are highly active…”
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11
Synthesis and in vitro and in silico studies of 1H- and 2H-1,2,3-triazoles as antichagasic agents
Published in Bioorganic chemistry (01-11-2021)“…[Display omitted] •Two series of 5-amino 1H- and 2H-1,2,3-Triazoles were synthesized.•Both series have been evaluated against epimastigote form of Trypanosoma…”
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12
An Overview of Hydrogen Production from Renewable Sources and Its Main Applications
Published in ChemistrySelect (Weinheim) (18-09-2024)“…There is a misconception that sustainability is only related to greenhouse gas emissions into the atmosphere, and that this is the only risk to which the…”
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13
HUISGEN AND HIS ADVENTURES IN A PLAYGROUND OF MECHANISMS AND NOVEL REACTIONS
Published in Química Nova (01-02-2021)“…The death of professor Rolf Huisgen (1920-2020) was announced on March 26th 2020, in the midst of the COVID-19 pandemic. Professor Huisgen was professor…”
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14
A Stereoselective, Base‐free, Palladium‐Catalyzed Heck Coupling Between 3‐halo‐1,4‐Naphthoquinones and Vinyl‐1H‐1,2,3‐Triazoles
Published in ChemistrySelect (Weinheim) (27-06-2022)“…A stereoselective, base‐free Heck coupling between 1,4‐naphthoquinone and 1H‐1,2,3‐triazole derivatives was reported for the first time. This study shows that…”
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15
1,2,3-Triazolyl-4-oxoquinolines: A feasible beginning for promising chemical structures to inhibit oseltamivir-resistant influenza A and B viruses
Published in Bioorganic & medicinal chemistry (15-12-2015)“…We described the synthesis of a new congener series of 1,2,3-triazolyl-4-oxoquinolines and evaluated their ability to inhibit oseltamivir (OST)-resistant…”
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Synthesis, molecular docking, and biological activity of thioether derived from juglone in preclinical models of chronic myeloid leukemia
Published in Computational toxicology (01-11-2021)“…[Display omitted] In this work, 16 new thio-1,4-naphthoquinones were synthesized, and their antiproliferative effects against tumor cell lines SK-MEL-19,…”
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Synthesis of β-Substituted meso-Tetraaryl-21,23-dithiaporphyrins by Heck Reaction
Published in European journal of organic chemistry (01-09-2015)“…meso‐Tetraphenyl‐21,23‐dithiaporphyrin was selectively monobrominated at one β‐pyrrolic position in good yields. This dithiaporphyrin was then functionalized…”
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Synthesis, cytotoxicity and mechanistic evaluation of 4-oxoquinoline-3-carboxamide derivatives: finding new potential anticancer drugs
Published in Molecules (Basel, Switzerland) (22-05-2014)“…As part of a continuing search for new potential anticancer candidates, we describe the synthesis, cytotoxicity and mechanistic evaluation of a series of…”
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Chemotherapeutics against Infectious Diseases: Syntheses and Biological Targets - Part II
Published in Current topics in medicinal chemistry (01-01-2021)Get more information
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20
A Stereoselective, Base‐free, Palladium‐Catalyzed Heck Coupling Between 3‐halo‐1,4‐Naphthoquinones and Vinyl‐1 H ‐1,2,3‐Triazoles
Published in ChemistrySelect (Weinheim) (27-06-2022)“…A stereoselective, base‐free Heck coupling between 1,4‐naphthoquinone and 1 H ‐1,2,3‐triazole derivatives was reported for the first time. This study shows…”
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