Search Results - "da Rocha, Fabio Fagundes"

Neuropharmacological assessment in mice and molecular docking of piperazine derivative LQFM212 by Moreira, Lorrane Kelle, de Brito, Adriane Ferreira, Fontana, Crisciele, de Carvalho, Flávio Souza, Sanz, Germán, Vaz, Boniek Gontijo, Lião, Luciano Morais, da Rocha, Fábio Fagundes, Verli, Hugo, Menegatti, Ricardo, Costa, Elson Alves

“…•LQFM212 is a new piperazine derivative with pharmacological central activity.•LQFM212 has an anxiolytic-like activity with no cognitive impairment.•The action…”
Get full text

Preclinical data on morpholine (3,5-di-tertbutyl-4-hydroxyphenyl) methanone induced anxiolysis by Cabral, Iara Barbosa, de Lima Moreira, Caroline Vitória, Rodrigues, Ana Carolina Cavalcante, da Silva Moreira, Lorrane Kelle, Pereira, Jhon Kennedy Alves, Gomides, Christian Dias, Lião, Luciano M., Machado, Lucas S., Vaz, Boniek G., da Cunha, Luiz Carlos, de Oliveira Neto, Jerônimo Raimundo, da Silva-Júnior, Edeildo Ferreira, de Aquino, Thiago Mendonça, da Silva Santos-Júnior, Paulo Fernando, Silva, Osmar N., da Rocha, Fábio Fagundes, Costa, Elson Alves, Menegatti, Ricardo, Fajemiroye, James O.

“…Trimetozine is used to be indicated for the treatment of mental illnesses, particularly anxiety. The present study provides data on the pharmacological profile…”
Get full text

Monoamine Involvement in the Antidepressant-Like Effect of β-Caryophyllene by de Oliveira, Danillo Ramos, da Silva, Dayane Moreira, Florentino, Iziara Ferreira, de Brito, Adriane Ferreira, Fajemiroye, James Oluwagbamigbe, da Silva, Daiany Priscilla Bueno, da Rocha, Fabio Fagundes, Costa, Elson Alves, Galdino, Pablinny Moreira

“…Major depressive disorder is a psychiatric disorder that affects 4.4% of the population worldwide. Although the majority of antidepressant drugs ameliorate…”
Get more information

Involvement of the monoamine system in antidepressant-like properties of 4-(1-phenyl-1h-pyrazol-4-ylmethyl)-piperazine-1-carboxylic acid ethyl ester by Galdino, Pablinny Moreira, de Oliveira, Danillo Ramos, Florentino, Iziara Ferreira, Fajemiroye, James Oluwagbamigbe, Valadares, Marize Campos, de Moura, Soraia Santana, da Rocha, Fábio Fagundes, de Lima, Thereza Christina Monteiro, Costa, Elson Alves, Menegatti, Ricardo

“…Piperazinic derivatives have therapeutic potential by acting as analgesic, antidepressant-like, anticonvulsant and antipsychotic in preclinical studies. In…”
Get full text

Sodium selenite supplementation during pregnancy and lactation promotes anxiolysis and improves mnemonic performance in wistar rats' offspring by Laureano-Melo, Roberto, Império, Güínever Eustáquio do, da Silva-Almeida, Claudio, Kluck, George Eduardo Gabriel, Cruz Seara, Fernando de Azevedo, da Rocha, Fábio Fagundes, da Silveira, Anderson Luiz Bezerra, Reis, Luís Carlos, Ortiga-Carvalho, Tania Maria, da Silva Côrtes, Wellington

“…Selenium is a micronutrient which is part of selenoprotein molecules and participates in a vast number of physiological roles and, among them, we have fetal…”
Get full text

Behavioral profile assessment in offspring of Swiss mice treated during pregnancy and lactation with caffeine by Laureano-Melo, Roberto, da Silveira, Anderson Luiz Bezerra, de Azevedo Cruz Seara, Fernando, da Conceição, Rodrigo Rodrigues, da Silva-Almeida, Cláudio, Marinho, Bruno Guimarães, da Rocha, Fábio Fagundes, Reis, Luís Carlos, Côrtes, Wellington da Silva

“…The association between caffeine consumption and various psychiatric manifestations has long been observed. The objective was to assess the behavioral profile…”
Get full text

Evaluation of the antinociceptive and anti-inflammatory effects of the acetone extract from Anacardium occidentale L by Vanderlinde, Frederico Argollo, Landim, Higor Frutuoso, Costa, Elson Alves, Galdino, Pablinny Moreira, Maciel, Maria Aparecida Medeiros, Anjos, Gineide Conceição dos, Malvar, David do Carmo, Côrtes, Wellington da Silva, Rocha, Fábio Fagundes da

“…The stem bark of Anacardium occidentale L. (Anacardiaceae), commonly called cashew, is used in Brazilian traditional medicine for the treatment of gastric and…”
Get full text

Antidepressive-Like Property of Dichloromethane Fraction of Pimenta pseudocaryophyllus and Relevance of Monoamine Metabolic Enzymes by Fajemiroye, James Oluwagbamigbe, Martins, José Luís Rodrigues, Ghedini, Paulo César, Galdino, Pablinny Morreira, Paula, Joelma Abadia Marciano de, Realino de Paula, José, Da Rocha, Fabio Fagundes, Costa, Elson Alves

“…Pimenta pseudocaryophyllus popularly referred to as craveiro is considered as a calming agent in different local preparations. The present study attempted to…”
Get full text

LQFM212, a piperazine derivative, exhibits potential antioxidant effect as well as ameliorates LPS-induced behavioral, inflammatory and oxidative changes by Moreira, Lorrane Kelle da Silva, Turones, Larissa Córdova, Campos, Hericles Mesquita, Nazareth, Aline Martins, Thomaz, Douglas Vieira, Gil, Eric de Souza, Ghedini, Paulo César, Rocha, Fábio Fagundes da, Menegatti, Ricardo, Fajemiroye, James Oluwagbamigbe, Costa, Elson Alves

“…Oxidative stress, impaired antioxidant defense and neuroinflammation are often associated with the onset and progression of neuropsychiatric diseases…”
Get full text

Tert-butyl 4-((1-phenyl-1H-pyrazol-4-yl) methyl) piperazine-1-carboxylate (LQFM104)– New piperazine derivative with antianxiety and antidepressant-like effects: Putative role of serotonergic system by da Silva, Dayane Moreira, Sanz, Germán, Vaz, Boniek Gontijo, de Carvalho, Flávio Silva, Lião, Luciano Morais, de Oliveira, Danillo Ramos, Moreira, Lorrane Kelle da Silva, Cardoso, Carina Sofia, de Brito, Adriane Ferreira, da Silva, Daiany Priscilla Bueno, da Rocha, Fabio Fagundes, Santana, Ianca Gontijo Cavalcante, Galdino, Pablinny Moreira, Costa, Elson Alves, Menegatti, Ricardo

“…[Display omitted] •LQFM104 is a new synthesized psychoactive piperazine derivative.•LQFM104 has anxiolytic- and antidepressant-like activities in mice.•These…”
Get full text

Behavioral Profile Assessment in Offspring of Swiss Mice Underwent to Neonatal Treatment with D‐fenfluramine by Melo, Roberto Laureano, Silveira, Anderson Luis Bezerra, Seara, Fernando Azevedo Cruz, da Rocha, Fabio Fagundes, Reis, Luis Carlos, Cortes, Wellington Silva

“…Abstract only Serotonin (5‐HT) exerts an important role in the central nervous system embryogenesis of mammals, influencing directly several brain systems…”
Get full text

Behavioral Profile Assessment in Offspring of Swiss MiceTreated During Pregnancy and Lactation with Caffeine by Silveira, Anderson Luiz Bezerra, Melo, Roberto Laureano, Seara, Fernando Azevedo Cruz, Almeida, Cláudio Silva, da Rocha, Fabio Fagundes, Santos, Alex Sander Nunes, Marinho, Bruno Guimarães, Reis, Luís Carlos, Cortes, Wellington Silva

“…Abstract only The objective was to assess the behavioral profile in offspring of Swiss mice treated during pregnancy and lactation with caffeine. For this…”
Get full text

Estresse de desmame influencia a resposta in vitro de fator de necrose tumoral em potros Mangalarga Marchador by Bruno Ferreira Spindola, Paulo de Tarso Landgraf Botteon, Fabio Fagundes da Rocha, Simone Bizerra Calado, Rita de Cassia Campbell Machado Botteon, Isabella Manes Souto Mayor da Mota Rodrigues, Lucas Moura Marinho

“…O desmame precoce é um período crítico para uma saúde e o desenvolvimento de potros, devido a uma queda de resistência imunológica (imonocompetência) tornando…”
Get full text

Gastroprotective Effect of oenothein B: a Romising Macrocyclic Ellagitannin by Martins, José Luis Rodrigues, Silva, Dayane Moreira da, Florentino, Iziara Ferreira, Fajemiroye, James Oluwagbamigbe, Hungria Pinto, Emerith Mayra, Oliveira, Thiago Sardinha de, Rocha, Fábio Fagundes da, Souza Gil, Eric de, Ferreira, Anderson Luiz, Santos, Suzana da Costa, Silva, Osmar Nascimento, Costa, Elson Alves

“…A peptic ulcer disease is a significant gastrointestinal disorder with a high prevalence of 80% in developing countries and 40% in developed countries…”
Get full text