Search Results - "da Palma, Telma Martins"

A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice by Mehrotra, Shikhar, Al-Khami, Amir A, Klarquist, Jared, Husain, Shahid, Naga, Osama, Eby, Jonathan M, Murali, Anuradha K, Lyons, Gretchen E, Li, Mingli, Spivey, Natali D, Norell, Håkan, Martins da Palma, Telma, Onicescu, Georgiana, Diaz-Montero, C Marcela, Garrett-Mayer, Elizabeth, Cole, David J, Le Poole, I Caroline, Nishimura, Michael I

“…Recent advancements in T cell immunotherapy suggest that T cells engineered with high-affinity TCR can offer better tumor regression. However, whether a…”
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Transduction with the Antioxidant Enzyme Catalase Protects Human T Cells against Oxidative Stress by Ando, Takashi, Mimura, Kousaku, Johansson, C. Christian, Hanson, Mikael G, Mougiakakos, Dimitrios, Larsson, Charlotte, Martins da Palma, Telma, Sakurai, Daiju, Norell, Hakan, Li, Mingli, Nishimura, Michael I, Kiessling, Rolf

“…Patients with diseases characterized by chronic inflammation, caused by infection or cancer, have T cells and NK cells with impaired function. The underlying…”
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CD34-based enrichment of genetically engineered human T cells for clinical use results in dramatically enhanced tumor targeting by Norell, Håkan, Zhang, Yi, McCracken, James, Martins da Palma, Telma, Lesher, Aaron, Liu, Yueying, Roszkowski, Jeffrey J, Temple, Anquanette, Callender, Glenda G, Clay, Timothy, Orentas, Rimas, Guevara-Patiño, José, Nishimura, Michael I

“…Objective clinical responses can be achieved in melanoma patients by infusion of T cell receptor (TCR) gene transduced T cells. Although promising, the therapy…”
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Inhibition of superoxide generation upon T-cell receptor engagement rescues Mart-1(27-35)-reactive T cells from activation-induced cell death by Norell, Håkan, Martins da Palma, Telma, Lesher, Aaron, Kaur, Navtej, Mehrotra, Meenal, Naga, Osama S, Spivey, Natalie, Olafimihan, Seye, Chakraborty, Nitya G, Voelkel-Johnson, Christina, Nishimura, Michael I, Mukherji, Bijay, Mehrotra, Shikhar

“…Cytotoxic T lymphocytes (CTL) may undergo massive expansion upon appropriate antigenic stimulation. Homeostasis is maintained by a subsequent "contraction" of…”
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Inhibition of Superoxide Generation upon T-Cell Receptor Engagement Rescues Mart-127-35-Reactive T Cells from Activation-Induced Cell Death by NORELL, Hakan, DA PALMA, Telma Martins, NISHIMURA, Michael I, MUKHERJI, Bijay, MEHROTRA, Shikhar, LECHER, Aaron, KAUR, Navtej, MEHROTRA, Meenal, NAGA, Osama S, SPIVEY, Natalie, OLAFIMIHAN, Seye, CHAKRABORTY, Nitya G, VOELKEL-JOHNSON, Christina

“…Cytotoxic T lymphocytes (CTL) may undergo massive expansion upon appropriate antigenic stimulation. Homeostasis is maintained by a subsequent “contraction” of…”
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Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide induction by Meyers-Needham, Marisa, Lewis, Jocelyn A, Gencer, Salih, Sentelle, R David, Saddoughi, Sahar A, Clarke, Christopher J, Hannun, Yusuf A, Norell, Haakan, da Palma, Telma Martins, Nishimura, Michael, Kraveka, Jacqueline M, Khavandgar, Zohreh, Murshed, Monzur, Cevik, M Ozgur, Ogretmen, Besim

“…Sonic hedgehog (SHh) signaling is important in the pathogenesis of various human cancers, such as medulloblastomas, and it has been identified as a valid…”
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Tyrosinase reactive T cells can eliminate large established human melanoma tumors in vivo (48.23) by Martins da Palma, Telma, Spivey, Natali, Naga, Osama, Al-Khami, Amir, Graves, Michael, Lesher, Aaron, Ferrone, Soldano, Mehrotra, Shikhar, Norell, Håkan, Nishimura, Michael

“…Objective clinical responses of melanoma can be achieved by infusion of tumor infiltrating lymphocytes or T cell receptor (TCR) gene transduced T cells. To…”
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A Co-Receptor Independent Transgenic Human TCR Mediates Anti-Tumor and Anti-Self Immunity in Mice by Mehrotra, Shikhar, Al-Khami, Amir A., Klarquist, Jared, Husain, Shahid, Naga, Osama, Eby, Jonathan M., Murali, Anuradha K., Lyons, Gretchen E., Li, Mingli, Spivey, Natali D., Norell, Håkan, Martins da Palma, Telma, Onicescu, Georgiana, Diaz-Montero, C. Marcela, Garrett-Mayer, Elizabeth, Cole, David J., Le Poole, I. Caroline, Nishimura, Michael I.

“…Recent advancements in T cell immunotherapy suggest that T cells engineered with high affinity T cell receptors (TCR) can offer better tumor regression…”
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Inhibition of Superoxide Generation upon TCR Engagement Rescues Mart-127-35 reactive T cells from Activation Induced Cell Death by Norell, Håkan, da Palma, Telma Martins, Lesher, Aaron, Kaur, Navtej, Mehrotra, Meenal, Naga, Osama S., Spivey, Natalie, Olafimihan, Seye, Chakraborty, Nitya G., Voelkel-Johnson, Christina, Nishimura, Michael I., Mukherji, Bijay, Mehrotra, Shikhar

“…Cytolytic T lymphocytes (CTL) undergo massive expansion upon appropriate antigenic stimulation. Homeostasis is maintained by a subsequent “contraction” of…”
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Development of a transgenic mouse with high affinity TCR reactive to human tyrosinase epitope (41.39) by MEHROTRA, SHIKHAR, Li, Mingli, Lyons, Gretchen E, Spivey, Natalie, Palma, Telma Martins da, Naga, Osama S, Norell, Haakan R, Diaz-Montero, C. Marcela, Cole, David J, Nishimura, Michael I

“…Most tumor-associated antigen epitopes recognized on human melanomas by autologous T lymphocytes are derived from nonmutated self-proteins. Given the belief…”
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Tyrosinase reactive T cells reject or edit established human melanomas in vivo by Martins da Palma, Telma Raquel

“…Adoptive transfer of T cell receptor (TCR) gene transduced T cells can mediate dramatic tumor regressions in melanoma patients. However, improvements in these…”
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Tyrosinase reactive T cells reject or edit established human melanomas in vivo by Martins da Palma, Telma Raquel

“…Adoptive transfer of T cell receptor (TCR) gene transduced T cells can mediate dramatic tumor regressions in melanoma patients. However, improvements in these…”
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