Search Results - "da Fontoura Galváo, Gustavo"

Association of Variants in FCGR2A, PTPN2, and GM-CSF with Cerebral Cavernous Malformation: Potential Biomarkers for a Symptomatic Disease by da Fontoura Galváo, Gustavo, Fontes-Dantas, Fabrícia Lima, da Silva, Elielson Veloso, Alves-Leon, Soniza Vieira, de Souza, Jorge Marcondes

“…Cerebral Cavernous Malformations (CCM) predispose patients to a lifetime risk of seizures and symptomatic hemorrhage. Only a small percentage of people…”
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Early and long-term outcome of surgical versus conservative management for intracranial cerebral cavernous malformation: Meta-analysis of reconstructed time-to-event data by da Fontoura Galvão, Gustavo, Verly, Gabriel, Valença, Pablo, Domingues, Flávio Sampaio, da Silva, Marcello Reis, Marcondes, Jorge

“…Cerebral cavernous malformations (CCMs) present challenges in clinical management due to a lack of definitive evidence from clinical trials. Surgical…”
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Infratentorial Cerebral Cavernous Malformation May be a Risk Factor for Symptomatic Bleeding and Precocity of Symptoms: A Multicenter, Propensity Score Matched, Case-Control Study by Galvão, Gustavo da Fontoura, Filho, Ricardo Castro, Cunha, Alexandre Alexandre Martins, Soares, Andre Guimarães, Filho, Marcos Antônio Dellaretti, de Souza, Jorge Marcondes

“…Cerebral Cavernous Malformation (CCM) is one of the most common types of vascular malformation of the central nervous system. Intracerebral hemorrhage,…”
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Elevated proportion of TLR2- and TLR4-expressing Th17-like cells and activated memory B cells was associated with clinical activity of cerebral cavernous malformations by Castro, Camilla, Oyamada, Hugo A A, Cafasso, Marcos Octávio S D, Lopes, Lana M, Monteiro, Clarice, Sacramento, Priscila M, Alves-Leon, Soniza Vieira, da Fontoura Galvão, Gustavo, Hygino, Joana, de Souza, Jorge Paes Barreto Marcondes, Bento, Cleonice A M

“…Recent evidences have suggested the involvement of toll-like receptor (TLR)-4 in the pathogenesis of cerebral cavernous malformations (CCM). Elevated frequency…”
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Surgery alone versus surgery plus adjuvant radiotherapy for WHO grade 2 meningioma: meta-analysis of reconstructed time-to-event data by Verly, Gabriel, Bresciani, Lucas, Delfino, Thiffany, Nascimento, Marcos, Magill, Stephen T., Galvão, Gustavo da Fontoura

“…Introduction WHO Grade 2 meningiomas present diagnostic and management challenges. Surgery, particularly gross total resection (GTR), is crucial, often…”
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Comprehensive analysis of Novel mutations in CCM1/KRIT1 and CCM2/MGC4607 and their clinical implications in Cerebral Cavernous malformations by Galvão, Gustavo da Fontoura, Trefilio, Luisa Menezes, Salvio, Andreza Lemos, da Silva, Elielson Veloso, Alves-Leon, Soniza Vieira, Fontes-Dantas, Fabrícia Lima, de Souza, Jorge Marcondes

“…Cerebral Cavernous Malformations (CCM) is a genetic disease characterized by vascular abnormalities in the brain and spinal cord, affecting 0.4-0.5 % of the…”
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Comprehensive CCM3 Mutational Analysis in Two Patients with Syndromic Cerebral Cavernous Malformation by da Fontoura Galvão, Gustavo, da Silva, Elielson Veloso, Trefilio, Luisa Menezes, Alves-Leon, Soniza Vieira, Fontes-Dantas, Fabrícia Lima, de Souza, Jorge Marcondes

“…Cerebral cavernous malformation (CCM) is a vascular disease that affects the central nervous system, which familial form is due to autosomal dominant mutations…”
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First Report of Concomitant Pathogenic Mutations Within MGC4607/CCM2 and KRIT1/CCM1 in a Familial Cerebral Cavernous Malformation Patient by da Fontoura Galvão, Gustavo, Veloso da Silva, Elielson, Fontes-Dantas, Fabrícia Lima, Filho, Ricardo Castro, Alves-Leon, Soniza, Marcondes de Souza, Jorge

“…Familial cerebral cavernous malformations (CCM) are among the most common vascular malformations of the central nervous system (CNS) and are linked to…”
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Novel CCM1 (KRIT1) Mutation Detection in Brazilian Familial Cerebral Cavernous Malformation: Different Genetic Variants in Inflammation, Oxidative Stress, and Drug Metabolism Genes Affect Disease Aggressiveness by Fontes-Dantas, Fabrícia Lima, da Fontoura Galvão, Gustavo, Veloso da Silva, Elielson, Alves-Leon, Soniza, Cecília da Silva Rêgo, Cláudia, Garcia, Diogo Gomes, Marques, Suelen Adriani, Blanco Martinez, Ana Maria, Reis da Silva, Marcello, Marcondes de Souza, Jorge

“…Cerebral cavernous malformations (CCMs) are vascular capillary anomalies with a dysfunctional endothelial adherent junction profile, depicting hemorrhage and…”
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Asymptomatic cerebral cavernous angiomas associated with plasma marker signature by Chehuen Bicalho, Vítor, da Fontoura Galvão, Gustavo, Lima Fontes-Dantas, Fabrícia, Paulo da Costa Gonçalves, João, Dutra de Araujo, Amanda, Carolina França, Laise, Emílio Corrêa Leite, Paulo, Campolina Vidal, Diego, Castro Filho, Ricardo, Vieira Alves-Leon, Soniza, Marcondes de Souza, Jorge

“…•Biological behavior of CCM is still controversial.•Plasma levels of IL-27 and GM-CSF might be related to an asymptomatic clinical phenotype.•Biomarker formula…”
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Receiver operating characteristic curve analysis on intensive care unit prognostic prediction scores in patients sustaining subarachnoid hemorrhage: A Brazilian retrospective study by da Fontoura Galvão, Gustavo, Novo, Caio Moreno Perret, Spolidoro, Leonardo Baron, Filho, Cesar Augusto Ferreira Alves, Fernandes, Simone Maria Lindemayer, Salame, José Massoud, Filho, Sion Divan, Missaka, Herbert

“…Objectives: To evaluate patient's Acute Physiology and Chronic Health Evaluation System II (APACHE II), Sequential Organ Failure Assessment (SOFA), and…”
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Clinical features, hemorrhage risk and epilepsy outcomes of familial cerebral cavernous malformation: A 20-year observational pragmatic single-center study by Galvão, Gustavo da Fontoura, Neumann, Vinicius Barbosa, Verly, Gabriel, Valença, Pablo, Cunha, Alexandre Martins, da Silva, Marcello Reis, Domingues, Flavio Sampaio, de Souza, Jorge Marcondes

“…•Long-term follow-up reveals ongoing symptomatic risks in fCCM patients.•Baseline epilepsy and age over 20 predict higher seizure risk.•60 % of fCCM patients…”
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Supratotal Resection Versus Gross Total Resection for Isocitrate Dehydrogenase-Wildtype Glioblastoma and Grade 4 Isocitrate Dehydrogenase-Mutant Astrocytoma: Meta-Analysis of Individual Patient Data by Verly, Gabriel, Delfino, Thiffany, Bresciani, Lucas, Oliveira, Matheus, Oyon, Daniel, Chandler, James, Galvão, Gustavo da Fontoura

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Clinical Features, Hemorrhage Risk and Epilepsy Outcomes of Familial Cerebral Cavernous Malformation: a 20-year Observational Pragmatic Single-Center Study: Clinical Outcomes of Familial CCM: a 20-year Observational Study by Galvão, Gustavo da Fontoura, Neumann, Vinicius Barbosa, Verly, Gabriel, Valença, Pablo, Cunha, Alexandre Martins, da Silva, Marcello Reis, Domingues, Flavio Sampaio, de Souza, Jorge Marcondes

“…Familial Cerebral Cavernous Malformations (fCCMs) are rare, hereditary conditions characterized by multiple central nervous system lesions. Despite their…”
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First Report of Concomitant Pathogenic Mutations Within MGC4607/CCM2 and KRIT1/CCM1 in a Familial Cerebral Cavernous Malformation Patient by da Fontoura Galvão, Gustavo, Veloso da Silva, Elielson, Fontes-Dantas, Fabrícia Lima, Filho, Ricardo Castro, Alves-Leon, Soniza, Marcondes de Souza, Jorge

“…BACKGROUNDFamilial cerebral cavernous malformations (CCM) are among the most common vascular malformations of the central nervous system (CNS) and are linked…”
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Novel CCM1 (KRIT1) Mutation Detection in Brazilian Familial Cerebral Cavernous Malformation: Different Genetic Variants in Inflammation, Oxidative Stress, and Drug Metabolism Genes Affect Disease Aggressiveness by Fontes-Dantas, Fabrícia Lima, da Fontoura Galvão, Gustavo, Veloso da Silva, Elielson, Alves-Leon, Soniza, Cecília da Silva Rêgo, Cláudia, Garcia, Diogo Gomes, Marques, Suelen Adriani, Blanco Martinez, Ana Maria, Reis da Silva, Marcello, Marcondes de Souza, Jorge

“…BACKGROUNDCerebral cavernous malformations (CCMs) are vascular capillary anomalies with a dysfunctional endothelial adherent junction profile, depicting…”
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