Search Results - "da Fonseca Martins, Alessandra Marcia"
-
1
The role of TLR9 on Leishmania amazonensis infection and its influence on intranasal LaAg vaccine efficacy
Published in PLoS neglected tropical diseases (01-02-2019)“…Leishmania (L.) amazonensis is one of the etiological agents of cutaneous leishmaniasis (CL) in Brazil. Currently, there is no vaccine approved for human use…”
Get full text
Journal Article -
2
Characterization of Sv129 Mice as a Susceptible Model to Leishmania amazonensis
Published in Frontiers in medicine (29-05-2019)“…Leishmaniasis is a complex of neglected diseases caused by parasites of the genus , such as , the ethiologic agent of diffuse cutaneous leishmaniasis in…”
Get full text
Journal Article -
3
NKG2C+CD57+ natural killer cells with senescent features are induced during cutaneous leishmaniasis and accumulate in patients with lesional healing impairment
Published in Clinical and experimental immunology (09-08-2024)“…Natural killer (NK) cells include different subsets with diverse effector capacities that are poorly understood in the context of parasitic diseases. Here, we…”
Get full text
Journal Article -
4
Immunomodulating role of IL-10-producing B cells in Leishmania amazonensis infection
Published in Cellular immunology (01-12-2018)“…•Leishmania amazonensis infection induced IL-10 production by follicular B cells.•Infected Xid mice had delayed lesion growth and lower levels of IL-10…”
Get full text
Journal Article -
5
Subtilisin of Leishmania amazonensis as Potential Druggable Target: Subcellular Localization, In Vitro Leishmanicidal Activity and Molecular Docking of PF-429242, a Subtilisin Inhibitor
Published in Current issues in molecular biology (09-05-2022)“…Subtilisin proteases, found in all organisms, are enzymes important in the post-translational steps of protein processing. In Leishmania major and L. donovani,…”
Get full text
Journal Article -
6
Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis
Published in Stem cell research & therapy (31-08-2020)“…Background Leishmaniasis is a neglected disease caused by Leishmania spp. One of its characteristics is an imbalance of host immune responses to foster…”
Get full text
Journal Article -
7
Effects of Bone Marrow Mesenchymal Stromal Cell Therapy in Experimental Cutaneous Leishmaniasis in BALB/c Mice Induced by Leishmania amazonensis
Published in Frontiers in immunology (10-08-2017)“…Cutaneous leishmaniasis remains both a public health and a therapeutic challenge. To date, no ideal therapy for cutaneous leishmaniasis has been identified,…”
Get full text
Journal Article -
8
Dietary Vitamin D3 Deficiency Increases Resistance to Leishmania (Leishmania) amazonensis Infection in Mice
Published in Frontiers in cellular and infection microbiology (09-04-2019)“…The leishmaniases are a group of diseases caused by parasites, which have different clinical manifestations. is endemic in South America and causes cutaneous…”
Get full text
Journal Article -
9
Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice
Published in Vaccines (Basel) (01-08-2022)“…Despite the intramuscular route being the most used vaccination strategy against SARS-CoV-2, the intradermal route has been studied around the globe as a…”
Get full text
Journal Article -
10
MPLA and AddaVax® Adjuvants Fail to Promote Intramuscular LaAg Vaccine Protectiveness against Experimental Cutaneous Leishmaniasis
Published in Microorganisms (Basel) (11-06-2021)“…There is so far no vaccine approved for human leishmaniasis, mainly because of the lack of appropriate adjuvants. This study aimed to evaluate in mice the…”
Get full text
Journal Article -
11
Intranasal delivery of LaAg vaccine improves immunity of aged mice against visceral Leishmaniasis
Published in Acta tropica (01-04-2024)“…•The age of mice directly affects leishmania parasitemia.•Use of the LaAg vaccine intranasally helps in the process of controlling parasite in young and…”
Get full text
Journal Article -
12
B-1 lymphocytes are able to produce IL-10, but is not pathogenic during Leishmania (Leishmania) amazonensis infection
Published in Immunobiology (1979) (01-01-2020)“…Over the years research has found an association between B lymphocytes and pathogenesis during Leishmania sp. infections. Recently we demonstrated that B-2…”
Get full text
Journal Article -
13
Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum
Published in Frontiers in immunology (30-06-2022)“…The SARS-CoV-2 pandemic has had a social and economic impact worldwide, and vaccination is an efficient strategy for diminishing those damages. New adjuvant…”
Get full text
Journal Article -
14
Efficacy of intranasal LaAg vaccine against Leishmania amazonensis infection in partially resistant C57Bl/6 mice
Published in Parasites & vectors (06-10-2016)“…We have previously demonstrated that intranasal vaccination of highly susceptible BALB/c mice with whole Leishmania amazonensis antigens (LaAg) leads to…”
Get full text
Journal Article -
15
Care conceptions from the nursing residents' point of view: links between theory and practice/Concepcoes de cuidado na perspectiva de residentes de enfermagem: os nexos entre pratica e teoria/Concepciones de cuidado en la perspectiva de residentes de enfermería: los nexos entre práctica y teoría
Published in Revista enfermagem UERJ (01-07-2013)“…This research aimed at identifying conceptions of care by nursing residents in a teaching hospital, and at assessing the relation they make between theory and…”
Get full text
Journal Article -
16
Care conceptions from the nursing residents' point of view: links between theory and practice/Concepcoes de cuidado na perspectiva de residentes de enfermagem: os nexos entre pratica e teoria/ Concepciones de cuidado en la perspectiva de residentes de enfermeria: los nexos entre practca y teoria
Published in Revista enfermagem UERJ (01-12-2012)“…This research aimed at identifying conceptions of care by nursing residents in a teaching hospital, and at assessing the relation they make between theory and…”
Get full text
Journal Article -
17
Concepções de cuidado na perspectiva de residentes de enfermagem: os nexos entre prática e teoria [Care conceptions from the nursing residents’ point of view: links between theory and practice]
Published in Revista enfermagem UERJ (01-04-2013)“…O objetivo desta pesquisa foi identificar a concepção de cuidado dos enfermeiros residentes de enfermagem de um hospital universitário e verificar como eles…”
Get full text
Journal Article