Search Results - "da Costa, Rafael M."
-
1
Nrf2 as a Potential Mediator of Cardiovascular Risk in Metabolic Diseases
Published in Frontiers in pharmacology (12-04-2019)“…Free radicals act as secondary messengers, modulating a number of important biological processes, including gene expression, ion mobilization in transport…”
Get full text
Journal Article -
2
Melatonin prevents overproduction of reactive oxygen species and vascular dysfunction induced by cyclophosphamide
Published in Life sciences (1973) (01-02-2024)“…Overproduction of reactive oxygen species (ROS) is a pathologic hallmark of cyclophosphamide toxicity. For this reason, antioxidant compounds emerge as…”
Get full text
Journal Article -
3
Modulation of Vascular Function by Perivascular Adipose Tissue: Sex Differences
Published in Current pharmaceutical design (01-01-2020)“…In addition to the endothelium, the perivascular adipose tissue (PVAT) has been described to be involved in the local modulation of vascular function by…”
Get more information
Journal Article -
4
Aryl hydrocarbon receptor (AhR) activation contributes to high‐fat diet‐induced vascular dysfunction
Published in British journal of pharmacology (01-06-2022)“…Background and Purpose Metabolic and vascular dysfunction are common features of obesity. Aryl hydrocarbon receptor (AhR) regulates lipid metabolism and…”
Get full text
Journal Article -
5
Increased O -GlcNAcylation of Endothelial Nitric Oxide Synthase Compromises the Anti-contractile Properties of Perivascular Adipose Tissue in Metabolic Syndrome
Published in Frontiers in physiology (06-04-2018)“…Under physiological conditions, the perivascular adipose tissue (PVAT) negatively modulates vascular contractility. This property is lost in experimental and…”
Get full text
Journal Article -
6
NADPH oxidase 4-derived hydrogen peroxide counterbalances testosterone-induced endothelial dysfunction and migration
Published in American journal of physiology: endocrinology and metabolism (01-07-2024)“…High levels of testosterone (Testo) are associated with cardiovascular risk by increasing reactive oxygen species (ROS) formation. NADPH oxidases (NOX) are the…”
Get more information
Journal Article -
7
Independent and joint associations of cardiorespiratory fitness and weight status with health-related quality of life among Brazilian adolescents
Published in Quality of life research (01-07-2023)“…Purpose To investigate the independent and joint associations of cardiorespiratory fitness and body mass index (BMI) with five dimensions of Health-Related…”
Get full text
Journal Article -
8
Pregnancy decreases O-GlcNAc-modified proteins in systemic arteries of normotensive and spontaneously hypertensive rats
Published in Life sciences (1973) (01-02-2021)“…We determined the role played by O-linked N-acetylglucosamine (O-GlcNAc) of proteins in systemic arteries during late pregnancy in normotensive and…”
Get full text
Journal Article -
9
Novel glucopyranoside C2-derived 1,2,3-triazoles displaying selective inhibition of O-GlcNAcase (OGA)
Published in Carbohydrate research (01-01-2019)“…O-GlcNAcylation or O-GlcNAc modification is a post-translational modification of several proteins responsible for fundamental cellular processes. Dysregulation…”
Get full text
Journal Article -
10
Alpha 1-acid glycoprotein is upregulated in severe COVID-19 patients and decreases neutrophil NETs in SARS-CoV-2 infection
Published in Cytokine (Philadelphia, Pa.) (01-04-2024)“…Orosomucoid, or alpha-1 acid glycoprotein (AGP), is a major acute-phase protein expressed in response to systemic injury and inflammation. AGP has been…”
Get full text
Journal Article -
11
Patterns of Objectively and Self-Reported Sedentary Behavior in Children and Adolescents Living With Human Immunodeficiency Virus: The PositHIVe Health Study
Published in Pediatric exercise science (01-02-2020)“…Sedentary behavior (SB) has been shown to be associated with unhealthy outcomes in children, and it is not clear whether children living with human…”
Get more information
Journal Article -
12
Pathology in Practice
Published in Journal of the American Veterinary Medical Association (02-02-2022)Get full text
Journal Article -
13
Abstract 13776: Alpha 1-Acid Glycoprotein is Involved With Neutrophil Nets in COVID-19
Published in Circulation (New York, N.Y.) (08-11-2022)“…IntroductionOrosomucoid also named Alpha-1 Acid Glycoprotein(AGP) is a major acute-phase protein and is increased in response to systemic injury and…”
Get full text
Journal Article