Search Results - "d’Oiron, R."

Common themes and challenges in hemophilia care: a multinational perspective by Stoffman, J., Andersson, N. G., Branchford, B., Batt, K., D'Oiron, R., Escuriola Ettingshausen, C., Hart, D. P., Jiménez Yuste, V., Kavakli, K., Mancuso, M. E., Nogami, K., Ramírez, C., Wu, R.

“…Objective: To identify ways that provision of hemophilia care can be maximized at the local level, irrespective of available resources or cultural or…”
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Achievements, challenges and unmet needs for haemophilia patients with inhibitors: Report from a symposium in Paris, France on 20 November 2014 by Dargaud, Y, Pavlova, A, Lacroix-Desmazes, S, Fischer, K, Soucie, M, Claeyssens, S, Scott, D W, d'Oiron, R, Lavigne-Lissalde, G, Kenet, G, Escuriola Ettingshausen, C, Borel-Derlon, A, Lambert, T, Pasta, G, Négrier, C

“…Over the past 20 years, there have been many advances in haemophilia treatment that have allowed patients to take greater control of their disease. However,…”
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Malignant disease in the haemophilic population: moving towards a management consensus? by Astermark, J., Makris, M., Mauser-Bunschoten, E., Nemes, L., D'oiron, R., Oldenburg, J., Ingerslev, J.

“…Summary The Malignancy in Haemophilia Workshop Group convened a consensus working group of haematologists and oncologists to review topics related to…”
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Characterization of four novel molecular changes in the promoter region of the factor VIII gene by Nougier, C., Roualdes, O., Fretigny, M., d'Oiron, R., Costa, C., Negrier, C., Vinciguerra, C.

“…Summary Haemophilia A (HA) is an X‐linked recessive bleeding disorder, caused by a wide variety of mutations in the factor VIII (F8) gene, leading to…”
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Prophylactic and therapeutic recombinant factor VIIa administration to patients with Glanzmann's thrombasthenia: results of an international survey by Poon, M‐C., D'Oiron, R., Von Depka, M., Khair, K., Négrier, C., Karafoulidou, A., Huth‐Kuehne, A., Morfini, M.

“…Background: Antibodies to glycoprotein (GP) IIb‐IIIa and/or HLA may render platelet transfusions ineffective to stop bleeding or to cover surgery in patients…”
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Cancer detection and management in patients with haemophilia: a retrospective European multicentre study by Biron-Andreani, C., de Moerloose, P., D'oiron, R., Chambost, H., Schved, J.-F., Hermans, C.

“…Summary Lymphomas or hepatocarcinomas related to blood‐borne transmitted diseases are well‐known malignancies in persons with haemophilia (PWH). However,…”
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Use of Haemate® P as immune tolerance induction in patients with severe haemophilia A who failed previous induction attempts: a multicentre observational study by Rothschild, C., D'oiron, R., Borel-derlon, A., Gruel, Y., Navarro, R., Negrier, C.

“…Summary Immune tolerance induction (ITI) can eliminate factor VIII (FVIII) inhibitory antibodies that appear during FVIII replacement therapy. If first‐line…”
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A systematic approach to controlling problem bleeds in patients with severe congenital haemophilia A and high-titre inhibitors by TEITEL, J., BERNTORP, E., COLLINS, P., D'OIRON, R., EWENSTEIN, B., GOMPERTS, E., GOUDEMAND, J., GRINGERI, A., KEY, N., LEISSINGER, C., MONAHAN, P., YOUNG, G.

“…The presence of inhibitory antibodies to clotting factors complicates the treatment of bleeding in haemophilia patients. For patients with high‐titre…”
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Mild hemophilia A fortuitously discovered during Henoch-Schönlein purpura by Joly, B, d'Oiron, R, Desconclois, C, Bendelac, L, Rafowicz, A, Meyzer, C, Labrune, P, Veyradier, A

“…Henoch-Schönlein purpura is a common form of immunological vasculitis in children. Hemophilia A is a genetic disorder, inherited in a X-linked recessive…”
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Molecular analysis of the fibrinogen gene cluster in 16 patients with congenital afibrinogenemia : novel truncating mutations in the FGA and FGG genes by NEERMAN-ARBEZ, M, DE MOERLOOSE, P, RIPOLL, L, VERVEL, C, D'OIRON, R, STAEGER, P, ANTONARAKIS, S. E, MORRIS, M. A, HONSBERGER, A, PARLIER, G, ARNUTI, B, BIRON, C, BORG, J.-Y, EBER, S, MEILI, E, PETER-SALONEN, K

“…Congenital afibrinogenemia is an autosomal recessive disorder characterized by the complete absence of detectable fibrinogen. We previously identified the…”
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Analysis of biological phenotypes from 42 patients with inherited factor VII deficiency: can biological tests predict the bleeding risk? by Giansily-Blaizot, M, Verdier, R, Biron-Adreani, C, Schved, JF, Bertrand, MA, Borg, JY, LeCam-Duchez, V, Briquel, ME, Chambost, H, Pouymayou, K, Dutrillaux, F, Favier, R, Martin-Toutain, I, Verdy, E, Gay, V, Goudemand, J, Navarro, R, Durin, A, d'Oiron, R, Lambert, T, Pernod, G, Barrot, C, Peynet, J, Bastenaire, B, Sie, P, Stieltjes, N, Torchet, MF, de Moerloose, P, Study group of FVII deficiency

“…Laboratory of Haematology, CHU Montpellier, France. m-giansily@chu-montpellier.fr BACKGROUND AND OBJECTIVES: Inherited factor VII (FVII) deficiency is a rare…”
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Molecular mechanisms of mild and moderate hemophilia A by Jacquemin, M., De Maeyer, M., D'Oiron, R., Lavend'Homme, R., Peerlinck, K., Saint‐Remy, J‐M.

“…Mutations responsible for mild/moderate hemophilia A were extensively characterized over the last 15 years and more than 200 mutations have been identified…”
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European principles of inhibitor management in patients with haemophilia: implications of new treatment options by Hermans, C, Giangrande, P. L. F, O'Mahony, B, de Kleijn, P, Bedford, M, Batorova, A, Blatný, J, Jansone, K, Astermark, J, Crato, M, d'Oiron, R, Dougall, A, Fijnvandraat, K, Granhaug, S, Jiménez-Yuste, V, JokiÄ, M, Lobet, S, Nolan, B, Peyvandi, F, Ryan, A

“…Keywords: Haemophilia, Guidelines, Inhibitors, Factor VIII, Factor IX, Bypassing agents, Emicizumab, Immune tolerance…”
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Imaging features of atypical bleeds in young patients with hemophilia by Gavrel, M., Rafowicz, A., d’Oiron, R., Franchi-Abella, S., Lambert, T., Adamsbaum, C.

“…Hemarthroses and muscle bleeds are well-known and well-documented complications in pediatric and young adult hemophilia patients. In contrast, deep bleeds in…”
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Mild/moderate haemophilia A: new insights into molecular mechanisms and inhibitor development by D'OIRON, R., PIPE, S. W., JACQUEMIN, M.

“…In mild/moderate haemophilia A (MHA) patients, many factor VIII (FVIII) gene defects, mainly missense mutations, have been identified and greatly improved the…”
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Protein A sepharose immunoadsorption: immunological and haemostatic effects in two cases of acquired haemophilia by Guillet, B., Kriaa, F., Huysse, M. G., Proulle, V., George, C., Tchernia, G., D'Oiron, R., Laurian, Y., Charpentier, B., Lambert, T., Dreyfus, M.

“…Acquired haemophilia is a life‐threatening disorder caused by circulating auto‐antibodies that inhibit factor VIII coagulant activity (FBIII:C)…”
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How I treat inhibitors in haemophilia by MAKRIS, M., HAY, C. R. M., GRINGERI, A., D'OIRON, R.

“…The management of patients with inhibitors is the greatest challenge facing haemophilia health professionals. Immune tolerance induction (ITI) can be…”
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Perioperative management and neuraxial analgesia in women with factor XI deficiency (<60 IU/dL): a French multicenter observational study of 314 pregnancies by Flaujac, C., Faille, D., Lavenu-Bombled, C., Drillaud, N., Lasne, D., Billoir, P., Desconclois, C., Touzet, L., Lebreton, A., Diaz-Cau, I., d’Oiron, R., Giansily-Blaizot, M., Wibaut, B., Beurrier, P., Volot, F., Rugeri, L., Roussel-Robert, V., de Raucourt, E.

“…Factor (F)XI deficiency is a rare bleeding disorder with a poor correlation between bleeding tendency and FXI level. Management of pregnant women with FXI…”
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Successful immune tolerance induction by FVIII in hemophilia A patients with inhibitor may occur without deletion of FVIII‐specific T cells by PAUTARD, B., D’OIRON, R., LI THIAO TE, V., LAVEND’HOMME, R., SAINT‐REMY, J.‐M., PEERLINCK, K., JACQUEMIN, M.

“…Background: The development of an inhibitor is the major complication facing patients with hemophilia A treated by administration of factor (F) VIII…”
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Identifying non-responsive bleeding episodes in patients with haemophilia and inhibitors: a consensus definition by BERNTORP, E., COLLINS, P., D'OIRON, R., EWING, N., GRINGERI, A., NÉGRIER, C., YOUNG, G.

“…Assessing response to treatment with bypassing agents presents a substantial challenge in the treatment of patients with haemophilia and inhibitors. Rapid and…”
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