Search Results - "d’Angelo, Michele"
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Neuronal Cells Rearrangement During Aging and Neurodegenerative Disease: Metabolism, Oxidative Stress and Organelles Dynamic
Published in Frontiers in molecular neuroscience (28-05-2019)“…Brain cells normally respond adaptively to oxidative stress or bioenergetic challenges, resulting from ongoing activity in neuronal circuits. During aging and…”
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Effects of the probiotic formulation SLAB51 in in vitro and in vivo Parkinson's disease models
Published in Aging (Albany, NY.) (09-03-2020)“…Parkinson is a common neurodegenerative disorder, characterized by motor and non-motor symptoms, including abnormalities in the gut function, which may appear…”
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3
Taurine and oxidative stress in retinal health and disease
Published in CNS neuroscience & therapeutics (01-04-2021)“…Retinal disorders are leading causes of blindness and are due to an imbalance between reactive oxygen species and antioxidant scavenger (in favor of…”
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4
PPARγ and Cognitive Performance
Published in International journal of molecular sciences (12-10-2019)“…Recent findings have led to the discovery of many signaling pathways that link nuclear receptors with human conditions, including mental decline and…”
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An Update on Graphene-Based Nanomaterials for Neural Growth and Central Nervous System Regeneration
Published in International journal of molecular sciences (02-12-2021)“…Thanks to their reduced size, great surface area, and capacity to interact with cells and tissues, nanomaterials present some attractive biological and…”
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The emerging role of probiotics in neurodegenerative diseases: new hope for Parkinson's disease?
Published in Neural regeneration research (01-04-2021)“…Neurodegenerative disease etiology is still unclear, but different contributing factors, such as lifestyle and genetic factors are involved. Altered components…”
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The Role of Stiffness in Cell Reprogramming: A Potential Role for Biomaterials in Inducing Tissue Regeneration
Published in Cells (Basel, Switzerland) (05-09-2019)“…The mechanotransduction is the process by which cells sense mechanical stimuli such as elasticity, viscosity, and nanotopography of extracellular matrix and…”
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DF2726A, a new IL-8 signalling inhibitor, is able to counteract chemotherapy-induced neuropathic pain
Published in Scientific reports (13-08-2019)“…Chemotherapy-induced peripheral neuropathy (CIPN) is a common dose-limiting side effect of several anti-neoplastics and a main cause of sensory disturbances in…”
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NSAIDs-dependent adaption of the mitochondria-proteasome system in immortalized human cardiomyocytes
Published in Scientific reports (27-10-2020)“…The progressive consumption growth of non-steroidal anti-inflammatory drugs (NSAIDs) has progressively raised the attention toward the gastrointestinal, renal,…”
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Brain incoming call from glia during neuroinflammation: Roles of extracellular vesicles
Published in Neurobiology of disease (15-10-2024)“…The functionality of the central nervous system (CNS) relies on the connection, integration, and the exchange of information among neural cells. The crosstalk…”
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Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance
Published in Stem cells international (01-01-2016)“…Among all solid tumors, the high-grade glioma appears to be the most vascularized one. In fact, “microvascular hyperplasia” is a hallmark of GBM. An altered…”
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The Involvement of PPARs in the Peculiar Energetic Metabolism of Tumor Cells
Published in International journal of molecular sciences (29-06-2018)“…Energy homeostasis is crucial for cell fate, since all cellular activities are strongly dependent on the balance between catabolic and anabolic pathways. In…”
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13
A State-of-the-Art of Functional Scaffolds for 3D Nervous Tissue Regeneration
Published in Frontiers in bioengineering and biotechnology (18-03-2021)“…Exploring and developing multifunctional intelligent biomaterials is crucial to improve next-generation therapies in tissue engineering and regenerative…”
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Early-life exposure to environmentally relevant concentrations of triclocarban impairs ocular development in zebrafish larvae
Published in Chemosphere (Oxford) (01-05-2023)“…Triclocarban (TCC), is an antimicrobial component in personal care products and it is one of the emerging contaminants since it has been detected in various…”
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Neuroprotective effects of the PPARβ/δ antagonist GSK0660 in in vitro and in vivo Parkinson's disease models
Published in Biological research (25-05-2023)“…The underlying mechanism of Parkinson's disease are still unidentified, but excitotoxicity, oxidative stress, and neuroinflammation are considered key actors…”
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Therapeutic advances in neural regeneration for Huntington's disease
Published in Neural regeneration research (01-09-2024)“…Huntington's disease is a neurodegenerative disease caused by the expansion mutation of a cytosine-adenine-guanine triplet in the exon 1 of the HTT gene which…”
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Sublethal exposure to propylparaben leads to lipid metabolism impairment in zebrafish early‐life stages
Published in Journal of applied toxicology (01-04-2020)“…Parabens are widely used in cosmetics, toiletries, food and pharmaceuticals. Toxicological effects of parabens on human lipid metabolism are not well…”
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Intranasal delivery of NGF rescues hearing impairment in aged SAMP8 mice
Published in Cell death & disease (13-09-2023)“…Hearing loss impacts the quality of life and affects communication resulting in social isolation and reduced well-being. Despite its impact on society and…”
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Brain Organoids: A Game-Changer for Drug Testing
Published in Pharmaceutics (01-04-2024)“…Neurological disorders are the second cause of death and the leading cause of disability worldwide. Unfortunately, no cure exists for these disorders, but the…”
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PPARs and Energy Metabolism Adaptation during Neurogenesis and Neuronal Maturation
Published in International journal of molecular sciences (26-06-2018)“…Peroxisome proliferator activated receptors (PPARs) are a class of ligand-activated transcription factors, belonging to the superfamily of receptors for…”
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