Search Results - "d'Exaerde, Alban de Kerchove"

Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders by Martin, Maud, Vermeiren, Simon, Bostaille, Naguissa, Eubelen, Marie, Spitzer, Daniel, Vermeersch, Marjorie, Profaci, Caterina P, Pozuelo, Elisa, Toussay, Xavier, Raman-Nair, Joanna, Tebabi, Patricia, America, Michelle, De Groote, Aurélie, Sanderson, Leslie E, Cabochette, Pauline, Germano, Raoul F V, Torres, David, Boutry, Sébastien, de Kerchove d'Exaerde, Alban, Bellefroid, Eric J, Phoenix, Timothy N, Devraj, Kavi, Lacoste, Baptiste, Daneman, Richard, Liebner, Stefan, Vanhollebeke, Benoit

“…The blood-brain barrier (BBB) protects the central nervous system (CNS) from harmful blood-borne factors. Although BBB dysfunction is a hallmark of several…”
Get full text

Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice by Oishi, Yo, Xu, Qi, Wang, Lu, Zhang, Bin-Jia, Takahashi, Koji, Takata, Yohko, Luo, Yan-Jia, Cherasse, Yoan, Schiffmann, Serge N., de Kerchove d’Exaerde, Alban, Urade, Yoshihiro, Qu, Wei-Min, Huang, Zhi-Li, Lazarus, Michael

“…Sleep control is ascribed to a two-process model, a widely accepted concept that posits homoeostatic drive and a circadian process as the major…”
Get full text

Error-related signaling in nucleus accumbens D2 receptor-expressing neurons guides inhibition-based choice behavior in mice by Nishioka, Tadaaki, Attachaipanich, Suthinee, Hamaguchi, Kosuke, Lazarus, Michael, de Kerchove d’Exaerde, Alban, Macpherson, Tom, Hikida, Takatoshi

“…Learned associations between environmental cues and the outcomes they predict (cue-outcome associations) play a major role in behavioral control, guiding not…”
Get full text

The Effect of Serotonin Receptor 5-HT1B on Lateral Inhibition between Spiny Projection Neurons in the Mouse Striatum by Pommer, Stefan, Akamine, Yumiko, Schiffmann, Serge N., de Kerchove d'Exaerde, Alban, Wickens, Jeffery R.

“…The principal neurons of the striatum, the spiny projection neurons (SPNs), make inhibitory synaptic connections with each other via collaterals of their main…”
Get full text

Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure by Walle, Roman, Petitbon, Anna, Fois, Giulia R., Varin, Christophe, Montalban, Enrica, Hardt, Lola, Contini, Andrea, Angelo, Maria Florencia, Potier, Mylène, Ortole, Rodrigue, Oummadi, Asma, De Smedt-Peyrusse, Véronique, Adan, Roger A., Giros, Bruno, Chaouloff, Francis, Ferreira, Guillaume, de Kerchove d’Exaerde, Alban, Ducrocq, Fabien, Georges, François, Trifilieff, Pierre

“…Accumulating evidence points to dysregulations of the Nucleus Accumbens (NAc) in eating disorders (ED), however its precise contribution to ED symptomatic…”
Get full text

Dopamine–endocannabinoid interactions mediate spike-timing-dependent potentiation in the striatum by Xu, Hao, Perez, Sylvie, Cornil, Amandine, Detraux, Bérangère, Prokin, Ilya, Cui, Yihui, Degos, Bertrand, Berry, Hugues, de Kerchove d’Exaerde, Alban, Venance, Laurent

“…Dopamine modulates striatal synaptic plasticity, a key substrate for action selection and procedural learning. Thus, characterizing the repertoire of…”
Get full text

Distinct Roles of Ventromedial versus Ventrolateral Striatal Medium Spiny Neurons in Reward-Oriented Behavior by Tsutsui-Kimura, Iku, Natsubori, Akiyo, Mori, Marina, Kobayashi, Kenta, Drew, Michael R., de Kerchove d’Exaerde, Alban, Mimura, Masaru, Tanaka, Kenji F.

“…The ventral striatum (VS) is a key brain center regulating reward-oriented behavior [1–4]. The VS can be anatomically divided into medial (VMS) and lateral…”
Get full text

Regulation of GluA1 phosphorylation by d‐amphetamine and methylphenidate in the cerebellum by Cutando, Laura, Puighermanal, Emma, Castell, Laia, Tarot, Pauline, Bertaso, Federica, Bonnavion, Patricia, Kerchove d'Exaerde, Alban, Isingrini, Elsa, Galante, Micaela, Dallerac, Glenn, Pascoli, Vincent, Lüscher, Christian, Giros, Bruno, Valjent, Emmanuel

“…Prescription stimulants, such as d‐amphetamine or methylphenidate are used to treat suffering from attention‐deficit hyperactivity disorder (ADHD). They…”
Get full text

Deletion of Maged1 in mice abolishes locomotor and reinforcing effects of cocaine by De Backer, Jean‐François, Monlezun, Stéphanie, Detraux, Bérangère, Gazan, Adeline, Vanopdenbosch, Laura, Cheron, Julian, Cannazza, Giuseppe, Valverde, Sébastien, Cantacorps, Lídia, Nassar, Mérie, Venance, Laurent, Valverde, Olga, Faure, Philippe, Zoli, Michele, De Backer, Olivier, Gall, David, Schiffmann, Serge N, de Kerchove d'Exaerde, Alban

“…Melanoma antigen genes (Mage) were first described as tumour markers. However, some of Mage are also expressed in healthy cells where their functions remain…”
Get full text

Adenosine A2A receptors in the olfactory bulb suppress rapid eye movement sleep in rodents by Wang, Yi-Qun, Li, Rui, Wang, Dian-Ru, Cherasse, Yoan, Zhang, Ze, Zhang, Meng-Qi, Lavielle, Oriana, McEown, Kristopher, Schiffmann, Serge N., de Kerchove d’Exaerde, Alban, Qu, Wei-Min, Lazarus, Michael, Huang, Zhi-Li

“…Rapid eye movement (REM) sleep behavior disorder in humans is often accompanied by a reduced ability to smell and detect odors, and olfactory bulbectomized…”
Get full text

Differential regulation of motor control and response to dopaminergic drugs by D1R and D2R neurons in distinct dorsal striatum subregions by Durieux, Pierre F, Schiffmann, Serge N, de Kerchove d'Exaerde, Alban

“…The dorsal striatum is critically involved in a variety of motor behaviours, including regulation of motor activity, motor skill learning and motor response to…”
Get full text

Balance Between Projecting Neuronal Populations of the Nucleus Accumbens Controls Social Behavior in Mice by Le Merrer, Julie, Detraux, Bérangère, Gandía, Jorge, De Groote, Aurélie, Fonteneau, Mathieu, de Kerchove d’Exaerde, Alban, Becker, Jérôme A.J.

“…Deficient social interactions are a hallmark of major neuropsychiatric disorders, and accumulating evidence points to altered social reward and motivation as…”
Get full text

Mammalian Target of Rapamycin-RhoA Signaling Impairments in Direct Striatal Projection Neurons Induce Altered Behaviors and Striatal Physiology in Mice by Rial, Daniel, Puighermanal, Emma, Chazalon, Marine, Valjent, Emmanuel, Schiffmann, Serge N., de Kerchove d’Exaerde, Alban

“…As an integrator of molecular pathways, mTOR (mammalian target of rapamycin) has been associated with diseases including neurodevelopmental, psychiatric, and…”
Get full text

Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs by Bonnavion, Patricia, Varin, Christophe, Fakhfouri, Ghazal, Martinez Olondo, Pilar, De Groote, Aurélie, Cornil, Amandine, Lorenzo Lopez, Ramiro, Pozuelo Fernandez, Elisa, Isingrini, Elsa, Rainer, Quentin, Xu, Kathleen, Tzavara, Eleni, Vigneault, Erika, Dumas, Sylvie, de Kerchove d’Exaerde, Alban, Giros, Bruno

“…The role of the striatum in motor control is commonly assumed to be mediated by the two striatal efferent pathways characterized by striatal projection neurons…”
Get full text

USP7/Maged1-mediated H2A monoubiquitination in the paraventricular thalamus: an epigenetic mechanism involved in cocaine use disorder by Cheron, Julian, Beccari, Leonardo, Hagué, Perrine, Icick, Romain, Despontin, Chloé, Carusone, Teresa, Defrance, Matthieu, Bhogaraju, Sagar, Martin-Garcia, Elena, Capellan, Roberto, Maldonado, Rafael, Vorspan, Florence, Bonnefont, Jérôme, de Kerchove d’Exaerde, Alban

“…The risk of developing drug addiction is strongly influenced by the epigenetic landscape and chromatin remodeling. While histone modifications such as…”
Get full text

It takes two to tango: Dorsal direct and indirect pathways orchestration of motor learning and behavioral flexibility by Bonnavion, Patricia, Fernández, Elisa Pozuelo, Varin, Christophe, de Kerchove d’Exaerde, Alban

“…The striatum as the main entry nucleus of the basal ganglia is long known to be critical for motor control. It integrates information from multiple cortical…”
Get full text

Aminopyridines correct early dysfunction and delay neurodegeneration in a mouse model of spinocerebellar ataxia type 1 by Hourez, Raphael, Servais, Laurent, Orduz, David, Gall, David, Millard, Isabelle, de Kerchove d'Exaerde, Alban, Cheron, Guy, Orr, Harry T, Pandolfo, Massimo, Schiffmann, Serge N

“…The contribution of neuronal dysfunction to neurodegeneration is studied in a mouse model of spinocerebellar ataxia type 1 (SCA1) displaying impaired motor…”
Get full text

Striatopallidal Neuron NMDA Receptors Control Synaptic Connectivity, Locomotor, and Goal-Directed Behaviors by Lambot, Laurie, Chaves Rodriguez, Elena, Houtteman, Delphine, Li, Yuquing, Schiffmann, Serge N, Gall, David, de Kerchove d'Exaerde, Alban

“…The basal ganglia (BG) control action selection, motor programs, habits, and goal-directed learning. The striatum, the principal input structure of BG, is…”
Get full text

Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output by Chávez, Marcelo, Ena, Sabrina, Van Sande, Jacqueline, de Kerchove d’Exaerde, Alban, Schurmans, Stéphane, Schiffmann, Serge N.

“…Ciliary transport is required for ciliogenesis, signal transduction, and trafficking of receptors to the primary cilium. Mutations in inositol polyphosphate…”
Get full text

Drug addiction: from bench to bedside by Cheron, Julian, Kerchove d’Exaerde, Alban de

“…Drug addiction is responsible for millions of deaths per year around the world. Still, its management as a chronic disease is shadowed by misconceptions from…”
Get full text