Search Results - "d'Aquino, Andrea"
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Metal–Organic Framework Nanoparticles
Published in Advanced materials (Weinheim) (01-09-2018)“…Due to their well‐defined 3D architectures, permanent porosity, and diverse chemical functionalities, metal–organic framework nanoparticles (MOF NPs) are an…”
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Reversible and Selective Encapsulation of Dextromethorphan and β‑Estradiol Using an Asymmetric Molecular Capsule Assembled via the Weak-Link Approach
Published in Journal of the American Chemical Society (01-02-2017)“…An allosterically regulated, asymmetric receptor featuring a binding cavity large enough to accommodate three-dimensional pharmaceutical guest molecules as…”
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Multi-State Dynamic Coordination Complexes Interconverted through Counterion-Controlled Phase Transfer
Published in Inorganic chemistry (05-04-2021)“…We studied a series of dynamic weak-link approach (WLA) complexes that can be shuttled between two immiscible solvents and switched between two structural…”
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Affinity-Directed Dynamics of Host–Guest Motifs for Pharmacokinetic Modulation via Supramolecular PEGylation
Published in Biomacromolecules (09-08-2021)“…Proteins are an impactful class of therapeutics but can exhibit suboptimal therapeutic performance, arising from poor control over the timescale of clearance…”
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Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors
Published in Science advances (08-04-2022)“…Adoptive cell therapy (ACT) has proven to be highly effective in treating blood cancers, but traditional approaches to ACT are poorly effective in treating…”
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Biomimetic Non-ergodic Aging by Dynamic-to-covalent Transitions in Physical Hydrogels
Published in ACS applied materials & interfaces (26-06-2024)“…Hydrogels are soft materials engineered to suit a multitude of applications that exploit their tunable mechanochemical properties. Dynamic hydrogels employing…”
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A Redox-Switchable, Allosteric Coordination Complex
Published in Journal of the American Chemical Society (07-11-2018)“…A redox-regulated molecular tweezer complex was synthesized via the weak-link approach. The PtII complex features a redox-switchable hemilabile ligand (RHL)…”
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Polyacrylamide‐based hydrogel coatings improve biocompatibility of implanted pump devices
Published in Journal of biomedical materials research. Part A (01-07-2023)“…The introduction of transcutaneous and subcutaneous implants and devices into the human body instigates fouling and foreign body responses (FBRs) that limit…”
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Highly-active nickel phosphide hydrotreating catalysts prepared in situ using nickel hypophosphite precursors
Published in Journal of catalysis (01-03-2016)“…[Display omitted] •Unsupported and supported Ni(H2PO2)2 reacts to form Ni2P at 468–561K.•Ni(H2PO2)2 precursors can be reduced in situ to give highly-active…”
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Effect of Particle Size on the Deep HDS Properties of Ni2P Catalysts
Published in Journal of physical chemistry. C (24-10-2019)“…Nickel phosphide nanoparticles encapsulated in mesoporous silica (Ni2P@mSiO2) were used to probe particle size effects in the deep hydrodesulfurization (HDS)…”
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Hydrogel‐Based Slow Release of a Receptor‐Binding Domain Subunit Vaccine Elicits Neutralizing Antibody Responses Against SARS‐CoV‐2
Published in Advanced materials (Weinheim) (01-12-2021)“…The development of effective vaccines that can be rapidly manufactured and distributed worldwide is necessary to mitigate the devastating health and economic…”
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Palladium(II) Weak-Link Approach Complexes Bearing Hemilabile N‑Heterocyclic Carbene–Thioether Ligands
Published in Inorganic chemistry (15-05-2017)“…A new class of homoligated palladium(II) weak-link approach (WLA) complexes bearing hemilabile N-heterocyclic carbene (NHC)–thioether ligands is reported…”
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13
An Allosterically Regulated, Four-State Macrocycle
Published in Inorganic chemistry (02-04-2018)“…Macrocycles capable of host–guest chemistry are an important class of structures that have attracted considerable attention because of their utility in…”
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Infinite Coordination Polymer Particles Composed of Stimuli-Responsive Coordination Complex Subunits
Published in Chemistry of materials (26-12-2017)Get full text
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Water‐Enhancing Gels Exhibiting Heat‐Activated Formation of Silica Aerogels for Protection of Critical Infrastructure During Catastrophic Wildfire
Published in Advanced materials (Weinheim) (01-10-2024)“…A promising strategy to address the pressing challenges with wildfire, particularly in the wildland‐urban interface (WUI), involves developing new approaches…”
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Stable High‐Concentration Monoclonal Antibody Formulations Enabled by an Amphiphilic Copolymer Excipient
Published in Advanced therapeutics (01-01-2023)“…Monoclonal antibodies (mAbs) are a staple in modern pharmacotherapy. Unfortunately, these biopharmaceuticals are limited by their tendency to aggregate in…”
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Ultra‐Fast Insulin–Pramlintide Co‐Formulation for Improved Glucose Management in Diabetic Rats
Published in Advanced science (01-11-2021)“…Dual‐hormone replacement therapy with insulin and amylin in patients with type 1 diabetes has the potential to improve glucose management. Unfortunately,…”
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Use of a biomimetic hydrogel depot technology for sustained delivery of GLP-1 receptor agonists reduces burden of diabetes management
Published in Cell reports. Medicine (21-11-2023)“…Glucagon-like peptide-1 (GLP-1) is an incretin hormone and neurotransmitter secreted from intestinal L cells in response to nutrients to stimulate insulin and…”
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A concerted two-prong approach to the in situ allosteric regulation of bifunctional catalysis
Published in Chemical science (Cambridge) (01-11-2016)“…Herein, we report the reversible "on-off" allosteric regulation of hydrogen-bond-donating (HBD)-Lewis base co-catalytic activity a concerted two-prong…”
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Environmental Performance of Innovative Ground-Source Heat Pumps with PCM Energy Storage
Published in Energies (Basel) (01-01-2020)“…Space conditioning is responsible for the majority of carbon dioxide emission and fossil fuel consumption during a building’s life cycle. The exploitation of…”
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