Search Results - "bes, J F"

Optimal linear-quadratic control of coupled parabolic-hyperbolic PDEs by Aksikas, I., Moghadam, A. Alizadeh, Forbes, J. F.

“…This paper focuses on the optimal control design for a system of coupled parabolic-hypebolic partial differential equations by using the infinite-dimensional…”
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Bypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised controlled trial by Adam, D J, Beard, J D, Cleveland, T, Bell, J, Bradbury, A W, Forbes, J F, Fowkes, F G R, Gillepsie, I, Ruckley, C V, Raab, G, Storkey, H

“…The treatment of rest pain, ulceration, and gangrene of the leg (severe limb ischaemia) remains controversial. We instigated the BASIL trial to compare the…”
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Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer by Howell, A, Cuzick, J, Baum, M, Buzdar, A, Dowsett, M, Forbes, J F, Hoctin-Boes, G, Houghton, J, Locker, G Y, Tobias, J S

“…The standard adjuvant endocrine treatment for postmenopausal women with hormone-receptor-positive localised breast cancer is 5 years of tamoxifen, but…”
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Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II by Sestak, I., Smith, S.G., Howell, A., Forbes, J.F., Cuzick, J.

“…Anastrozole reduces breast cancer risk in women at high risk, but implementing preventive therapy in clinical practice is difficult. Here, we evaluate…”
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Final 12-year follow-up of Surgery versus Surveillance in the UK Small Aneurysm Trial by Powell, J.T.

“…Background: The aim was to determine whether early open surgical repair would benefit patients with small abdominal aortic aneurysm compared with surveillance…”
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Systemic inflammation after critical illness: relationship with physical recovery and exploration of potential mechanisms by Griffith, David M, Lewis, Steff, Rossi, Adriano G, Rennie, Jillian, Salisbury, Lisa, Merriweather, Judith L, Templeton, Kate, Walsh, Timothy S

“…Physical recovery following critical illness is slow, often incomplete and is resistant to rehabilitation interventions. We aimed to explore the contribution…”
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Optimal control of coupled parabolic-hyperbolic non-autonomous PDEs: infinite-dimensional state-space approach by Aksikas, I., Moghadam, A. Alizadeh, Forbes, J. F.

“…This paper deals with the design of an optimal state-feedback linear-quadratic (LQ) controller for a system of coupled parabolic-hypebolic non-autonomous…”
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Improving decision making about clinical trial participation – a randomised controlled trial of a decision aid for women considering participation in the IBIS-II breast cancer prevention trial by Juraskova, I, Butow, P, Bonner, C, Bell, M L, Smith, A B, Seccombe, M, Boyle, F, Reaby, L, Cuzick, J, Forbes, J F

“…Background: Decision aids may improve informed consent in clinical trial recruitment, but have not been evaluated in this context. This study investigated…”
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A new pathological system for grading DCIS with improved prediction of local recurrence: results from the UKCCCR ANZ DCIS trial by Pinder, S E, Duggan, C, Ellis, I O, Cuzick, J, Forbes, J F, Bishop, H, Fentiman, I S, George, W D

“…Background: There is no consensus agreement regarding optimal management of locally excised ductal carcinoma in situ (DCIS) or features of greatest assistance…”
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Simulation study of SCR catalysts with individually adjusted ammonia dosing strategies by Opitz, B., Bendrich, M., Drochner, A., Vogel, H., Hayes, R.E., Forbes, J.F., Votsmeier, M.

“…[Display omitted] •A practical, model-based, ammonia dosing strategy is presented.•The dosing strategy is optimized and applied to SCR demonstration…”
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Bone fractures among postmenopausal patients with endocrine-responsive early breast cancer treated with 5 years of letrozole or tamoxifen in the BIG 1-98 trial by Rabaglio, M., Sun, Z., Price, K.N., Castiglione-Gertsch, M., Hawle, H., Thürlimann, B., Mouridsen, H., Campone, M., Forbes, J.F., Paridaens, R.J., Colleoni, M., Pienkowski, T., Nogaret, J.-M., Láng, I., Smith, I., Gelber, R.D., Goldhirsch, A., Coates, A.S.

“…To compare the incidence and timing of bone fractures in postmenopausal women treated with 5 years of adjuvant tamoxifen or letrozole for endocrine-responsive…”
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Multicentre randomised controlled trial of the clinical and cost-effectiveness of a bypass-surgery-first versus a balloon-angioplasty-first revascularisation strategy for severe limb ischaemia due to infrainguinal disease. The Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial by Bradbury, A W, Adam, D J, Bell, J, Forbes, J F, Fowkes, F G R, Gillespie, I, Raab, G, Ruckley, C V

“…To compare a 'bypass-surgery-first' with a 'balloon-angioplasty-first' revascularisation strategy in patients with severe limb ischaemia (SLI) due to…”
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Dose intensity in anthracycline-based chemotherapy for metastatic breast cancer: mature results of the randomised clinical trial ANZ 9311 by Ackland, Stephen. P., Gebski, V., Zdenkowski, N., Wilson, A., Green, M., Tees, S., Dhillon, H., Van Hazel, G., Levi, J., Simes, R. J., Forbes, J. F., Coates, A. S.

“…Purpose The separate impacts of dose and dose intensity of chemotherapy for metastatic breast cancer remain uncertain. The primary objective of this trial was…”
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The sequential use of endocrine treatment for advanced breast cancer: where are we? by Barrios, C., Forbes, J.F., Jonat, W., Conte, P., Gradishar, W., Buzdar, A., Gelmon, K., Gnant, M., Bonneterre, J., Toi, M., Hudis, C., Robertson, J.F.R.

“…Hormone receptor-positive advanced breast cancer is an increasing health burden. Although endocrine therapies are recognised as the most beneficial treatments…”
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Which patients benefit most from adjuvant aromatase inhibitors? Results using a composite measure of prognostic risk in the BIG 1-98 randomized trial by Viale, G., Regan, M.M., Dell'Orto, P., Mastropasqua, M.G., Maiorano, E., Rasmussen, B.B., MacGrogan, G., Forbes, J.F., Paridaens, R.J., Colleoni, M., Láng, I., Thürlimann, B., Mouridsen, H., Mauriac, L., Gelber, R.D., Price, K.N., Goldhirsch, A., Gusterson, B.A., Coates, A.S.

“…On average, aromatase inhibitors are better than tamoxifen when used as initial or sequential therapy for postmenopausal women with endocrine-responsive early…”
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Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms by Powell, J T, Brady, A R, Brown, L C, bes, J F

“…Early elective surgery may prevent rupture of abdominal aortic aneurysms, but mortality is 5–6%. The risk of rupture seems to be low for aneurysms smaller than…”
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LQ-boundary control of a diffusion-convection-reaction system by Mohammadi, L., Aksikas, I., Dubljevic, S., Forbes, J.F.

“…In this work, the boundary control of a distributed parameter system modelled by linear parabolic partial differential equations (PDEs) with spatially varying…”
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Relationships between CYP2D6 phenotype, breast cancer and hot flushes in women at high risk of breast cancer receiving prophylactic tamoxifen: results from the IBIS-I trial by Sestak, I, Kealy, R, Nikoloff, M, Fontecha, M, Forbes, J F, Howell, A, Cuzick, J

“…Background: Several studies have reported discordant results regarding the impact of the CYP2D6 phenotype on both the effectiveness and the degree of endocrine…”
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Predictors of early relapse in postmenopausal women with hormone receptor-positive breast cancer in the BIG 1-98 trial by Mauriac, L, Keshaviah, A, Debled, M, Mouridsen, H, Forbes, JF, Thürlimann, B, Paridaens, R, Monnier, A, Láng, I, Wardley, A, Nogaret, J-M, Gelber, RD, Castiglione-Gertsch, M, Price, KN, Coates, AS, Smith, I, Viale, G, Rabaglio, M, Zabaznyi, N, Goldhirsch, A

“…Background: Aromatase inhibitors are considered standard adjuvant endocrine treatment of postmenopausal women with hormone receptor-positive breast cancer, but…”
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Patterns and risk factors for locoregional failures after mastectomy for breast cancer: an International Breast Cancer Study Group report by Karlsson, P., Cole, B.F., Chua, B.H., Price, K.N., Lindtner, J., Collins, J.P., Kovács, A., Thürlimann, B., Crivellari, D., Castiglione-Gertsch, M., Forbes, J.F., Gelber, R.D., Goldhirsch, A., Gruber, G.

“…Rates and risk factors of local, axillary and supraclavicular recurrences can guide patient selection and target for postmastectomy radiotherapy (PMRT). Local,…”
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