Search Results - "Zypchen, Leslie"

Fludarabine and rituximab for relapsed or refractory hairy cell leukemia by Gerrie, Alina S., Zypchen, Leslie N., Connors, Joseph M.

“…The purine analogs, pentostatin and cladribine, induce high remission rates when used as first-line monotherapy for hairy cell leukemia (HCL); however,…”
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Solvent-Detergent Plasma for the Treatment of Thrombotic Microangiopathies: A Canadian Tertiary Care Centre Experience by Lee, Lauren J., Roland, Kristine J., Sreenivasan, Gayatri M., Zypchen, Leslie N., Ambler, Kimberley L.S., Yenson, Paul R.

“…Solvent detergent-treated plasma (SDP) is a pathogen-inactivated blood plasma, which in comparison to frozen plasma is associated with lower rates of allergic…”
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Dysmetabolic hyperferritinemia is associated with normal transferrin saturation, mild hepatic iron overload, and elevated hepcidin by Chen, Luke Y, Chang, Silvia D, Sreenivasan, Gayatri M, Tsang, Peter W, Broady, Raewyn C, Li, Charles H, Zypchen, Leslie N

“…Hyperferritinemia is common in individuals with the metabolic syndrome (dysmetabolic hyperferritinemia), but its pathophysiology and the degree to which it…”
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Macrocytosis in Mitochondrial DNA Deletion Syndromes by Almarzooqi, Farida, Vallance, Hilary, Mezei, Michelle, Lehman, Anna, Horvath, Gabriella, Rakic, Bojana, Zypchen, Leslie, Mattman, Andre

“…Large single mitochondrial DNA (mtDNA) deletion syndrome is a rare inborn error of metabolism with variable heteroplasmy levels and clinical phenotype among…”
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Diagnosis and management of iliofemoral deep vein thrombosis: clinical practice guideline by Liu, David, Peterson, Erica, Dooner, James, Baerlocher, Mark, Zypchen, Leslie, Gagnon, Joel, Delorme, Michael, Sing, Chad Kim, Wong, Jason, Guzman, Randolph, Greenfield, Gavin, Moodley, Otto, Yenson, Paul

“…Novel oral anticoagulants (rivaroxaban, dabigatran and apixaban) have also been shown to be effective for the treatment of acute DVT (see Appendix 2). Studies…”
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Fludarabine and Rituximab (FR) Is a Safe and Effective Treatment Alternative for Relapsed or Refractory Hairy Cell Leukemia (HCL) by Gerrie, Alina S., Zypchen, Leslie N., Connors, Joseph M.

“…Abstract 2454 Purine nucleoside analogs have been shown to produce high remission rates of 75–90% when used as first-line monotherapy for HCL. Long-term…”
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Clinical care pathway for the evaluation of patients with suspected VITT after ChAdOx1 nCoV-19 vaccination by Lee, Agnes Y.Y., Al Moosawi, Muntadhar, Peterson, Erica A., McCracken, Rita K., Wong, Steven K.W., Nicolson, Hamish, Chan, Vicky, Smith, Tyler, Wong, Michelle P., Lee, Lauren J., Griffiths, Cameron, Rahal, Bhavdeep, Parkin, Stephen, Afra, Kevin, Ambler, Kimberley, Chen, Luke Y.C., Field, Thalia S., Lindsay, Heather C., Lavoie, Martin, Li, Charles, Migneault, David, Naus, Monika, Piszczek, Jolanta, Rahmani, Poupak, Sreenivasan, Gayatri, Wan, Tony, Yee, Adrian, Zypchen, Leslie, Sweet, David

“…Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare complication after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) adenoviral…”
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Effects of Dabigatran and Rivaroxaban On Routine and Specialized Coagulation Assays: A Study Using Actual Patient Plasma Samples by Smith, Tyler W., Zypchen, Leslie, Carter, Cedric J., Tran, Annie, Colley, Pamela, Gin, Kenneth, Teal, Philip, Masri, Bassam A., Lee, Agnes Y.Y.

“…Abstract 23 To date, all published studies assessing the effects of the new oral anticoagulants dabigatran (dabi) and rivaroxaban (riva) on coagulation assays…”
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Monoclonal Proteins in Elderly Patients with Osteoporosis by Ambler, Kimberley, Song, Kevin W., Dian, Larry, Zypchen, Leslie

“…Background: Monoclonal proteins (M-proteins) and osteoporosis are both common in the elderly. For most patients with M-proteins and osteoporosis, the protein…”
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High Dose Melphalan and Autologous Stem Cell Transplantation In Light Chain and Light and Heavy Chain Deposition Disease: Hematologic and Renal Outcomes by Telio, David, Shepherd, John, Forrest, Donna L., Barnett, Michael J., Nevill, Thomas J., Zypchen, Leslie, Song, Kevin

“…Abstract 4597 Light chain deposition disease (LCDD) and light and heavy chain deposition disease (LHCDD) are plasma cell disorders characterized by pathologic…”
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Diagnosis and Treatment of Essential Thrombocythemia: Assessment of Current Clinical Practice by Lee, Vivian H Y, Peterson, Erica, Zypchen, Leslie, Foltz, Lynda M

“…Abstract 1903 Poster Board I-926 The discovery of the JAK2 V617F gene mutation has significantly altered the clinical diagnostic approach to the…”
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Thrombotic Complications and Risk of Myeloid Transformation in 164 Elderly Patients with Essential Thrombocythemia by Peterson, Erica, Zypchen, Leslie, Nitta, Janet, Berkowitz, Jonathan, Foltz, Lynda M

“…Abstract 2916 Poster Board II-892 Essential thrombocythemia (ET) is a myeloproliferative neoplasm associated with increased risk of both venous and arterial…”
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Published guidelines versus real‐life practice in the diagnosis and treatment of essential thrombocythemia by Peterson, Erica A., Zypchen, Leslie, Lee, Vivian H. Y., Nitta, Janet, Foltz, Lynda M.

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Pure red cell aplasia in a patient with adult‐onset Still's disease by Comondore, Vikram, Patterson, A. Caroline, Zypchen, Leslie, Dalal, Bakul

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Improved Survival of Patients with HIV-Related Systemic B-Cell Non-Hodgkin's Lymphoma (NHL) Expressing the Epstein-Barr Virus (EBV) in Malignant Cells Provided Patients Received HAART with Lymphoma Therapy by Ezzat, Hatoon, Filipinko, Douglas, Vickars, Linda M., Galbraith, Paul F., Li, Charles H., Murphy, Kevin, Montaner, Julio S.G., Harris, Marianne, Hogg, Robert S., Vercauteren, Suzanne, Leger, Chantal S., Zypchen, Leslie, Leitch, Heather A.

“…EBV infection of B-lymphocytes is known to promote cell proliferation and survival. In contrast to NHL in HIV-negative patients (pts), in whom ≤5% are…”
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Improvement in Outcome of Patients with CD30+ HIV-Related Systemic B-Cell Non-Hodgkin's Lymphoma (NHL) Providing HIV Infection Is Adequately Controlled by Ezzat, Hatoon, Wong, Jonathan C., Filipenko, Douglas, Vickars, Linda M., Galbraith, Paul F., Li, Charles H., Murphy, Kevin, Montaner, Julio S.G., Harris, Marianne, Hogg, Robert S., Vercauteren, Suzanne, Leger, Chantal S., Zypchen, Leslie, Leitch, Heather A.

“…Aberrant expression of the cell surface marker CD30 in systemic B-cell HIV-related NHL other than anaplastic large cell lymphoma (ALCL) has been reported. CD30…”
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BCL-2 Expression May Adversely Affect Outcome in HIV-Associated Systemic Diffuse Large B Cell Lymphoma by Ezzat, Hatoon, Filipenko, J. Doug, Vickars, Linda M., Galbraith, Paul F., Li, Charles H., Murphy, Kevin, Montaner, Julio, Harris, Marianne, Hogg, Robert, Vercauteren, Suzanne, Leger, Chantal S., Zypchen, Leslie, Leitch, Heather A.

“…BCL-2 expression in diffuse large B cell lymphoma (DLBCL) in HIV-negative patients (pts) is associated with inferior outcome, an effect at least partially…”
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Successful Allogeneic Hematopoietic Cell Transplantation Using Flu-Bu-ATG Conditioning for “Mono-MAC Syndrome” [GATA2 Deficiency] by Lad, Deepesh P, Zypchen, Leslie, Ryan, Frank, Elwood, Kevin, Holland, Steven, Hickstein, Dennis, MD, Nantel, Stephen H

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Collagenous colitis: a modifiable cause of diarrhoea in older people by Mackenzie, M, Zypchen, L, Ansari, S, Panju, A

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Pure red cell aplasia in a patient with adult-onset Still's disease by Comondore, Vikram, Patterson, A Caroline, Zypchen, Leslie, Dalal, Bakul

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