Search Results - "Zyner, Katherine G."

G-quadruplex DNA structures in human stem cells and differentiation by Zyner, Katherine G., Simeone, Angela, Flynn, Sean M., Doyle, Colm, Marsico, Giovanni, Adhikari, Santosh, Portella, Guillem, Tannahill, David, Balasubramanian, Shankar

“…The establishment of cell identity during embryonic development involves the activation of specific gene expression programmes and is underpinned by epigenetic…”
Get full text

Telomeric G-quadruplexes are a substrate and site of localization for human telomerase by Moye, Aaron L., Porter, Karina C., Cohen, Scott B., Phan, Tram, Zyner, Katherine G., Sasaki, Natsuki, Lovrecz, George O., Beck, Jennifer L., Bryan, Tracy M.

“…It has been hypothesized that G-quadruplexes can sequester the 3′ end of the telomere and prevent it from being extended by telomerase. Here we purify and…”
Get full text

Single-cell mapping of DNA G-quadruplex structures in human cancer cells by Hui, Winnie W. I., Simeone, Angela, Zyner, Katherine G., Tannahill, David, Balasubramanian, Shankar

“…G-quadruplexes (G4s) are four-stranded DNA secondary structures that form in guanine-rich regions of the genome. G4s have important roles in transcription and…”
Get full text

Genetic interactions of G-quadruplexes in humans by Zyner, Katherine G, Mulhearn, Darcie S, Adhikari, Santosh, Martínez Cuesta, Sergio, Di Antonio, Marco, Erard, Nicolas, Hannon, Gregory J, Tannahill, David, Balasubramanian, Shankar

“…G-quadruplexes (G4) are alternative nucleic acid structures involved in transcription, translation and replication. Aberrant G4 formation and stabilisation is…”
Get full text

Publisher Correction: Single-cell mapping of DNA G-quadruplex structures in human cancer cells by Hui, Winnie W. I., Simeone, Angela, Zyner, Katherine G., Tannahill, David, Balasubramanian, Shankar

Get full text

Telomerase Recruitment Requires both TCAB1 and Cajal Bodies Independently by Stern, J. Lewis, Zyner, Katherine G., Pickett, Hilda A., Cohen, Scott B., Bryan, Tracy M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Trans-omic profiling uncovers molecular controls of early human cerebral organoid formation by Chen, Carissa, Lee, Scott, Zyner, Katherine G., Fernando, Milan, Nemeruck, Victoria, Wong, Emilie, Marshall, Lee L., Wark, Jesse R., Aryamanesh, Nader, Tam, Patrick P.L., Graham, Mark E., Gonzalez-Cordero, Anai, Yang, Pengyi

“…Defining the molecular networks orchestrating human brain formation is crucial for understanding neurodevelopment and neurological disorders. Challenges in…”
Get full text

Landscape of G-quadruplex DNA structural regions in breast cancer by Hänsel-Hertsch, Robert, Simeone, Angela, Shea, Abigail, Hui, Winnie W. I., Zyner, Katherine G., Marsico, Giovanni, Rueda, Oscar M., Bruna, Alejandra, Martin, Alistair, Zhang, Xiaoyun, Adhikari, Santosh, Tannahill, David, Caldas, Carlos, Balasubramanian, Shankar

“…Response and resistance to anticancer therapies vary due to intertumor and intratumor heterogeneity 1 . Here, we map differentially enriched G-quadruplex (G4)…”
Get full text

Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G‑Quadruplex-Binding Small Molecule by Marchetti, Chiara, Zyner, Katherine G, Ohnmacht, Stephan A, Robson, Mathew, Haider, Shozeb M, Morton, Jennifer P, Marsico, Giovanni, Vo, Tam, Laughlin-Toth, Sarah, Ahmed, Ahmed A, Di Vita, Gloria, Pazitna, Ingrida, Gunaratnam, Mekala, Besser, Rachael J, Andrade, Ana C. G, Diocou, Seckou, Pike, Jeremy A, Tannahill, David, Pedley, R. Barbara, Evans, T. R. Jeffry, Wilson, W. David, Balasubramanian, Shankar, Neidle, Stephen

“…Human pancreatic ductal adenocarcinoma (PDAC) involves the dysregulation of multiple signaling pathways. A novel approach to the treatment of PDAC is…”
Get full text