Search Results - "Zygiel, Emily M"

The Human Innate Immune Protein Calprotectin Elicits a Multimetal Starvation Response in Pseudomonas aeruginosa by Nelson, Cassandra E, Huang, Weiliang, Zygiel, Emily M, Nolan, Elizabeth M, Kane, Maureen A, Oglesby, Amanda G

“…To combat infections, the mammalian host limits availability of essential transition metals such as iron (Fe), zinc (Zn), and manganese (Mn) in a strategy…”
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Transition Metal Sequestration by the Host-Defense Protein Calprotectin by Zygiel, Emily M, Nolan, Elizabeth M

“…In response to microbial infection, the human host deploys metal-sequestering host-defense proteins, which reduce nutrient availability and thereby inhibit…”
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Various mutations compensate for a deleterious lacZα insert in the replication enhancer of M13 bacteriophage by Zygiel, Emily M, Noren, Karen A, Adamkiewicz, Marta A, Aprile, Richard J, Bowditch, Heather K, Carroll, Christine L, Cerezo, Maria Abigail S, Dagher, Adelle M, Hebert, Courtney R, Hebert, Lauren E, Mahame, Gloria M, Milne, Stephanie C, Silvestri, Kelly M, Sutherland, Sara E, Sylvia, Alexandria M, Taveira, Caitlyn N, VanValkenburgh, David J, Noren, Christopher J, Hall, Marilena Fitzsimons

“…M13 and other members of the Ff class of filamentous bacteriophages have been extensively employed in myriad applications. The Ph.D. series of phage-displayed…”
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Nickel Sequestration by the Host-Defense Protein Human Calprotectin by Nakashige, Toshiki G, Zygiel, Emily M, Drennan, Catherine L, Nolan, Elizabeth M

“…The human innate immune protein calprotectin (CP, S100A8/S100A9 oligomer, calgranulin A/calgranulin B oligomer, MRP-8/MRP-14 oligomer) chelates a number of…”
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Exploring Iron Withholding by the Innate Immune Protein Human Calprotectin by Zygiel, Emily M, Nolan, Elizabeth M

“…Conspectus Calprotectin (CP) is a versatile player in the metal-withholding innate immune response, a process termed “nutritional immunity.” CP is a…”
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Bacterial Responses to Iron Withholding by Calprotectin by Obisesan, Adunoluwa O, Zygiel, Emily M, Nolan, Elizabeth M

“…Iron (Fe) plays important roles in both essential cellular processes and virulence pathways for many bacteria. Consequently, Fe withholding by the human innate…”
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The human innate immune protein calprotectin induces iron starvation responses in Pseudomonas aeruginosa by Zygiel, Emily M., Nelson, Cassandra E., Brewer, Luke K., Oglesby-Sherrouse, Amanda G., Nolan, Elizabeth M.

“…Most microbial pathogens have a metabolic iron requirement, necessitating the acquisition of this nutrient in the host. In response to pathogen invasion, the…”
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Heme protects Pseudomonas aeruginosa and Staphylococcus aureus from calprotectin-induced iron starvation by Zygiel, Emily M., Obisesan, Adunoluwa O., Nelson, Cassandra E., Oglesby, Amanda G., Nolan, Elizabeth M.

“…Pseudomonas aeruginosa and Staphylococcus aureus are opportunistic bacterial pathogens that cause severe infections in immunocompromised individuals and…”
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Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His 3 Asp Site by Nakashige, Toshiki G, Bowman, Sarah E J, Zygiel, Emily M, Drennan, Catherine L, Nolan, Elizabeth M

“…Calprotectin (CP, S100A8/S100A9 oligomer, MRP-8/MRP-14 oligomer) is a host-defense protein that sequesters nutrient transition metals from microbes. Each…”
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Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His3Asp Site by Nakashige, Toshiki G, Bowman, Sarah E. J, Zygiel, Emily M, Drennan, Catherine L, Nolan, Elizabeth M

“…Calprotectin (CP, S100A8/S100A9 oligomer, MRP-8/MRP-14 oligomer) is a host-defense protein that sequesters nutrient transition metals from microbes. Each…”
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Identification and characterization of mutant clones with enhanced propagation rates from phage-displayed peptide libraries by Nguyen, Kieu T.H., Adamkiewicz, Marta A., Hebert, Lauren E., Zygiel, Emily M., Boyle, Holly R., Martone, Christina M., Meléndez-Ríos, Carola B., Noren, Karen A., Noren, Christopher J., Hall, Marilena Fitzsimons

“…A target-unrelated peptide (TUP) can arise in phage display selection experiments as a result of a propagation advantage exhibited by the phage clone…”
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Various mutations compensate for a deleterious lacZ[alpha] insert in the replication enhancer of M13 bacteriophage by Zygiel, Emily M, Noren, Karen A, Adamkiewicz, Marta A, Aprile, Richard J, Bowditch, Heather K, Carroll, Christine L, Cerezo, Maria Abigail S, Dagher, Adelle M, Hebert, Courtney R, Hebert, Lauren E, Mahame, Gloria M, Milne, Stephanie C, Silvestri, Kelly M, Sutherland, Sara E, Sylvia, Alexandria M, Taveira, Caitlyn N, VanValkenburgh, David J, Noren, Christopher J, Hall, Marilena Fitzsimons

“…M13 and other members of the Ff class of filamentous bacteriophages have been extensively employed in myriad applications. The Ph.D. series of phage-displayed…”
Get full text