Search Results - "Zwizinski, Craig"

Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel gamma-secretase substrates by Nyborg, Andrew C, Ladd, Thomas B, Zwizinski, Craig W, Lah, James J, Golde, Todd E

“…The mammalian Vps10p sorting receptor family is a group of 5 type I membrane homologs (Sortilin, SorLA, and SorCS1-3). These receptors bind various cargo…”
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Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells by Sengul, Sule, Zwizinski, Craig, Batuman, Vecihi

“…We previously demonstrated that light chain (LC) endocytosis by human proximal tubule cells (PTCs) leads to production of cytokines through activation of…”
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P2-347: BRI2 (ITM2B) inhibits Aβ deposition by Miller, Victor M, Kim, Jungsu, Zou, Fanggeng, Levites, Yona, Jansen-West, Karen, Zwizinski, Craig W, Moore, Brenda D, Troendle, Fredrick J, Bann, Maralyssa, Verbeeck, Christophe, Price, Robert, Smithson, Lisa, Rangachari, Vijayaraghavan, Sonoda, Leilani, Wagg, Kayleigh, Ma, Li, Cangemi, David, Younkin, Samuel G, Pankratz, V. Shane, Petersen, Ronald C, Dickson, Dennis, Rosenberry, Terrone, Younkin, Steven G, Golde, Todd E

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Aβ40 Inhibits Amyloid Deposition In Vivo by Kim, Jungsu, Onstead, Luisa, Randle, Suzanne, Price, Robert, Smithson, Lisa, Zwizinski, Craig, Dickson, Dennis W., Golde, Todd, McGowan, Eileen

“…Numerous studies have established a pivotal role for Aβ42 in Alzheimer's disease (AD) pathogenesis. In contrast, although Aβ40 is the predominant form of…”
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BRI2 (ITM2b) Inhibits Aβ Deposition In Vivo by Kim, Jungsu, Miller, Victor M., Levites, Yona, West, Karen Jansen, Zwizinski, Craig W., Moore, Brenda D., Troendle, Fredrick J., Bann, Maralyssa, Verbeeck, Christophe, Price, Robert W., Smithson, Lisa, Sonoda, Leilani, Wagg, Kayleigh, Rangachari, Vijayaraghavan, Zou, Fanggeng, Younkin, Steven G., Graff-Radford, Neill, Dickson, Dennis, Rosenberry, Terrone, Golde, Todd E.

“…Analyses of the biologic effects of mutations in the BRI2 ( ITM2b ) and the amyloid β precursor protein ( APP ) genes support the hypothesis that cerebral…”
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Endocytosis of light chains induces cytokines through activation of NF-κB in human proximal tubule cells by Sengul, Sule, Zwizinski, Craig, Simon, Eric E., Kapasi, Aditi, Singhal, Pravin C., Batuman, Vecihi

“…Endocytosis of light chains induces cytokines through activation of NF-κB in human proximal tubule cells. In proteinuric states increased cytokine production…”
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Free radical-induced alterations of myocardial membrane proteins by Parinandi, N L, Zwizinski, C W, Schmid, H H

“…Rat myocardial membranes exposed to the free radical-generating systems, Fe2+/ascorbate, Cu2+/t-butylhydro-peroxide, linoleic acid hydroperoxide, and soybean…”
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A{szligbeta}40 Inhibits Amyloid Deposition In Vivo by Kim, Jungsu, Onstead, Luisa, Randle, Suzanne, Price, Robert, Smithson, Lisa, Zwizinski, Craig, Dickson, Dennis W, Golde, Todd, McGowan, Eileen

“…Numerous studies have established a pivotal role for A{szligbeta}42 in Alzheimer's disease (AD) pathogenesis. In contrast, although A{szligbeta}40 is the…”
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Cytotoxicity of myeloma light chains in cultured human kidney proximal tubule cells by Pote, Amy, Zwizinski, Craig, Simon, Eric E., Meleg-Smith, Suzanne, Batuman, Vecihi

“…We evaluated the effect of eight species of light chains on cultured human kidney proximal tubule cell proliferation. Exposure to light chains for 48 hours…”
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BRI2 (ITM2b) Inhibits A^b Deposition In Vivo by Kim, Jungsu, Miller, Victor M, Levites, Yona, West, Karen Jansen, Zwizinski, Craig W, Moore, Brenda D, Troendle, Fredrick J, Bann, Maralyssa, Verbeeck, Christophe, Price, Robert W, Smithson, Lisa, Sonoda, Leilani, Wagg, Kayleigh, Rangachari, Vijayaraghavan, Zou, Fanggeng, Younkin, Steven G, Graff-Radford, Neill, Dickson, Dennis, Rosenberry, Terrone, Golde, Todd E

“…Analyses of the biologic effects of mutations in the BRI2 (ITM2b) and the amyloid ^b precursor protein (APP) genes support the hypothesis that cerebral…”
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O3-03-03: Sortilin, SorLA, SorCS1: Just novel gamma-secretase substrates or more intimately involved in AD pathogenesis? by Nyborg, Andrew C., Levites, Yona, Ladd, Thomas B., Zwizinski, Craig W., Jansen, Karen, Golde, Todd E.

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BRI2 (ITM2b) Inhibits A{beta} Deposition In Vivo by Kim, Jungsu, Miller, Victor M, Levites, Yona, West, Karen Jansen, Zwizinski, Craig W, Moore, Brenda D, Troendle, Fredrick J, Bann, Maralyssa, Verbeeck, Christophe, Price, Robert W, Smithson, Lisa, Sonoda, Leilani, Wagg, Kayleigh, Rangachari, Vijayaraghavan, Zou, Fanggeng, Younkin, Steven G, Graff-Radford, Neill, Dickson, Dennis, Rosenberry, Terrone, Golde, Todd E

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Endocytosis of light chains induces cytokines through activation of NF-kappaB in human proximal tubule cells by Sengul, Sule, Zwizinski, Craig, Simon, Eric E, Kapasi, Aditi, Singhal, Pravin C, Batuman, Vecihi

“…In proteinuric states increased cytokine production through endocytosis of filtered proteins by proximal tubule cells (PTCs) has been proposed as a major…”
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Endocytosis of light chains induces cytokines through activation of NF- B in human proximal tubule cells by Sengul, Sule, Zwizinski, Craig, Simon, Eric E, Kapasi, Aditi, Singhal, Pravin C, Batuman, Vecihi

“…In proteinuric states increased cytokine production through endocytosis of filtered proteins by proximal tubule cells (PTCs) has been proposed as a major…”
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Abeta40 inhibits amyloid deposition in vivo by Kim, Jungsu, Onstead, Luisa, Randle, Suzanne, Price, Robert, Smithson, Lisa, Zwizinski, Craig, Dickson, Dennis W, Golde, Todd, McGowan, Eileen

“…Numerous studies have established a pivotal role for Abeta42 in Alzheimer's disease (AD) pathogenesis. In contrast, although Abeta40 is the predominant form of…”
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BRI2 (ITM2b) inhibits Abeta deposition in vivo by Kim, Jungsu, Miller, Victor M, Levites, Yona, West, Karen Jansen, Zwizinski, Craig W, Moore, Brenda D, Troendle, Fredrick J, Bann, Maralyssa, Verbeeck, Christophe, Price, Robert W, Smithson, Lisa, Sonoda, Leilani, Wagg, Kayleigh, Rangachari, Vijayaraghavan, Zou, Fanggeng, Younkin, Steven G, Graff-Radford, Neill, Dickson, Dennis, Rosenberry, Terrone, Golde, Todd E

“…Analyses of the biologic effects of mutations in the BRI2 (ITM2b) and the amyloid beta precursor protein (APP) genes support the hypothesis that cerebral…”
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Peroxidative damage to cardiac mitochondria. II. Immunological analysis of modified adenine nucleotide translocase by Girón-Calle, J, Zwizinski, C W, Schmid, H H

“…We have previously reported that treatment of isolated rat heart mitochondria with the free radical-generating system Cu2+/tert-butylhydroperoxide produces…”
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Peroxidative damage to cardiac mitochondria: identification and purification of modified adenine nucleotide translocase by Zwizinski, C W, Schmid, H H

“…Rat myocardial membranes exposed to free radical-generating systems exhibit both lipid peroxidation and protein alterations. The most sensitive protein, a…”
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Release of mitochondrial matrix proteins through a Ca2+-requiring, cyclosporin-sensitive pathway by Igbavboa, U, Zwizinski, C W, Pfeiffer, D R

“…Induction of the inner membrane permeability transition, normally associated with the release of small molecules and ions from the mitochondrial matrix, also…”
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Mechanisms of Membrane Assembly: Effects of Energy Poisons on the Conversion of Soluble M13 Coliphage Procoat to Membrane-Bound Coat Protein by Date, Takayasu, Zwizinski, Craig, Ludmerer, Steven, Wickner, William

“…The coat protein (gene 8 product) of coliphage M13 spans the host cell plasma membrane prior to its assembly into extruding virions. It is made as a soluble…”
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