Search Results - "Zvereva, Maria"
-
1
Nanopore Sequencing for De Novo Bacterial Genome Assembly and Search for Single-Nucleotide Polymorphism
Published in International journal of molecular sciences (01-08-2022)“…Nanopore sequencing (ONT) is a new and rapidly developing method for determining nucleotide sequences in DNA and RNA. It serves the ability to obtain long…”
Get full text
Journal Article -
2
Impact of G-Quadruplexes on the Regulation of Genome Integrity, DNA Damage and Repair
Published in Biomolecules (Basel, Switzerland) (27-08-2021)“…DNA G-quadruplexes (G4s) are known to be an integral part of the complex regulatory systems in both normal and pathological cells. At the same time, the…”
Get full text
Journal Article -
3
Functional duplication of Rap1 in methylotrophic yeasts
Published in Scientific reports (10-05-2019)“…The telomere regulator and transcription factor Rap1 is the only telomere protein conserved in yeasts and mammals. Its functional repertoire in budding yeasts…”
Get full text
Journal Article -
4
The TERT Promoter: A Key Player in the Fight for Cancer Cell Immortality
Published in Biochemistry (Moscow) (2023)“…The review describes the role of telomeres and telomerase in tumor progression, as well as various mechanisms of the activation of telomerase reverse…”
Get full text
Journal Article -
5
Advances of high-throughput sequencing for unraveling biotechnological potential of microalgal-bacterial communities
Published in Journal of applied phycology (01-08-2024)“…Although established biotechnological applications of microalgae e.g., the production of high-value metabolites is based on axenic cultures, exploitation of…”
Get full text
Journal Article -
6
Glycosylation of Receptor Binding Domain of SARS-CoV-2 S-Protein Influences on Binding to Immobilized DNA Aptamers
Published in International journal of molecular sciences (05-01-2022)“…Nucleic acid aptamers specific to S-protein and its receptor binding domain (RBD) of SARS-CoV-2 (severe acute respiratory syndrome-related coronavirus 2)…”
Get full text
Journal Article -
7
New DNA Plasmid Model for Studying DNA Mismatch Repair Response to the G4 Structure
Published in International journal of molecular sciences (05-01-2023)“…G-quadruplexes (G4s), the most widely studied alternative DNA structures, are implicated in the regulation of the key cellular processes. In recent years,…”
Get full text
Journal Article -
8
G-Quadruplex Formed by the Promoter Region of the hTERT Gene: Structure-Driven Effects on DNA Mismatch Repair Functions
Published in Biomedicines (03-08-2022)“…G-quadruplexes (G4s) are a unique class of noncanonical DNAs that play a key role in cellular processes and neoplastic transformation. Herein, we focused on…”
Get full text
Journal Article -
9
Responses of DNA Mismatch Repair Proteins to a Stable G-Quadruplex Embedded into a DNA Duplex Structure
Published in International journal of molecular sciences (20-11-2020)“…DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. The main MMR protein, MutS, was recently shown to recognize the…”
Get full text
Journal Article -
10
Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha DL1
Published in BMC genomics (27-11-2013)“…Hansenula polymorpha DL1 is a methylotrophic yeast, widely used in fundamental studies of methanol metabolism, peroxisome biogenesis and function, and also as…”
Get full text
Journal Article -
11
Detection of TERT Promoter Mutations as a Prognostic Biomarker in Gliomas: Methodology, Prospects, and Advances
Published in Biomedicines (21-03-2022)“…This article reviews the existing approaches to determining the promoter mutational status in patients with various tumoral diseases of the central nervous…”
Get full text
Journal Article -
12
Reactive Acrylamide-Modified DNA Traps for Accurate Cross-Linking with Cysteine Residues in DNA-Protein Complexes Using Mismatch Repair Protein MutS as a Model
Published in Molecules (Basel, Switzerland) (10-04-2022)“…Covalent protein capture (cross-linking) by reactive DNA derivatives makes it possible to investigate structural features by fixing complexes at different…”
Get full text
Journal Article -
13
Telomere length regulation by Rif1 protein from Hansenula polymorpha
Published in eLife (07-02-2022)“…Rif1 is a large multifaceted protein involved in various processes of DNA metabolism - from telomere length regulation and replication to double-strand break…”
Get full text
Journal Article -
14
Direct Determination of the Structure of Single Biopolymer Molecules Using Nanopore Sequencing
Published in Biochemistry (Moscow) (2024)“…This review highlights operational principles, features, and modern aspects of the development of third-generation sequencing technology of biopolymers…”
Get full text
Journal Article -
15
TERT Promoter Mutations as Simple and Non-Invasive Urinary Biomarkers for the Detection of Urothelial Bladder Cancer in a High-Risk Region
Published in International journal of molecular sciences (18-11-2022)“…Bladder cancer (BC) is the 10th most common cancer in the world. While there are FDA-approved urinary assays to detect BC, none have demonstrated sufficient…”
Get full text
Journal Article -
16
Activating Telomerase TERT Promoter Mutations and Their Application for the Detection of Bladder Cancer
Published in International journal of molecular sciences (21-08-2020)“…This review summarizes state-of-the-art knowledge in early-generation and novel urine biomarkers targeting the telomerase pathway for the detection and…”
Get full text
Journal Article -
17
Model of the SARS-CoV-2 Virus for Development of a DNA-Modified, Surface-Enhanced Raman Spectroscopy Sensor with a Novel Hybrid Plasmonic Platform in Sandwich Mode
Published in Biosensors (Basel) (01-09-2022)“…The recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has posed a great challenge for the development of ultra-fast methods for…”
Get full text
Journal Article -
18
Mixed Valence Copper(I,II) Binuclear Complexes with Unexpected Structure: Synthesis, Biological Properties and Anticancer Activity
Published in Journal of medicinal chemistry (24-07-2014)“…We have synthesized and characterized a panel of new binuclear mixed valence Cu(I,II) complexes containing substituted…”
Get full text
Journal Article -
19
Insights into the structure and function of Est3 from the Hansenula polymorpha telomerase
Published in Scientific reports (06-07-2020)“…Telomerase is a ribonucleoprotein enzyme, which maintains genome integrity in eukaryotes and ensures continuous cellular proliferation. Telomerase holoenzyme…”
Get full text
Journal Article -
20
Conserved G-Quadruplex-Forming Sequences in Mammalian TERT Promoters and Their Effect on Mutation Frequency
Published in Life (Basel, Switzerland) (29-06-2023)“…Somatic mutations in the promoter region of the human telomerase reverse transcriptase ( ) gene have been identified in many types of cancer. The promoter is…”
Get full text
Journal Article