Vitroceramic coatings deposited by laser ablation on Ti-Zr substrates for implantable medical applications with improved biocompatibility

The influence of vitroceramic coatings deposited onto Ti-Zr alloy plates on the biological properties of the final biomaterials was investigated. In this regard, two vitroceramic masses, different from compositional point of view, were synthesized by a sol-gel route, being subsequently converted int...

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Bibliographic Details
Published in:	Ceramics international Vol. 43; no. 7; pp. 5498 - 5504
Main Authors:	Busuioc, C., Voicu, G., Zuzu, I.D., Miu, D., Sima, C., Iordache, F., Jinga, S.I.
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 01-05-2017
Subjects:	Biocompatible coatings Implants Pulsed laser deposition Vitroceramics Pulsed laser deposition Vitroceramics Biocompatible coatings Implants
Online Access:	Get full text
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Summary:	The influence of vitroceramic coatings deposited onto Ti-Zr alloy plates on the biological properties of the final biomaterials was investigated. In this regard, two vitroceramic masses, different from compositional point of view, were synthesized by a sol-gel route, being subsequently converted into ceramic targets, suitable for ablation experiments. The film depositions were conducted in oxidative atmosphere, on substrates heated at 300 or 400°C. The coated samples were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy coupled with selected area diffraction and energy-dispersive X-ray spectroscopy, contact angle measurements and in vitro biological analyses (MTT cell proliferation assay, GSH oxidative stress assay, optical and fluorescence microscopy). All results sustained the applicative potential of Ti-Zr alloy substrates covered with a thin vitroceramic layer for medical implant applications.
ISSN:	0272-8842 1873-3956
DOI:	10.1016/j.ceramint.2017.01.070