Search Results - "Zuurbier, Kielen R"

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    Impaired meningeal lymphatic vessel development worsens stroke outcome by Yanev, Pavel, Poinsatte, Katherine, Hominick, Devon, Khurana, Noor, Zuurbier, Kielen R, Berndt, Marcus, Plautz, Erik J, Dellinger, Michael T, Stowe, Ann M

    “…The discovery of meningeal lymphatic vessels (LVs) has sparked interest in identifying their role in diseases of the central nervous system. Similar to…”
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    Trauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress by Egge, Nathan, Arneaud, Sonja L. B., Fonseca, Rene Solano, Zuurbier, Kielen R., McClendon, Jacob, Douglas, Peter M.

    Published in Nature communications (05-03-2021)
    “…Mechanical stimuli initiate adaptive signal transduction pathways, yet exceeding the cellular capacity to withstand physical stress results in death. The…”
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    Glycolytic preconditioning in astrocytes mitigates trauma-induced neurodegeneration by Solano Fonseca, Rene, Metang, Patrick, Egge, Nathan, Liu, Yingjian, Zuurbier, Kielen R, Sivaprakasam, Karthigayini, Shirazi, Shawn, Chuah, Ashleigh, Arneaud, Sonja LB, Konopka, Genevieve, Qian, Dong, Douglas, Peter M

    Published in eLife (02-09-2021)
    “…Concussion is associated with a myriad of deleterious immediate and long-term consequences. Yet the molecular mechanisms and genetic targets promoting the…”
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    Cytosolic dopamine determines hypersensitivity to blunt force trauma by Zuurbier, Kielen R., Solano Fonseca, Rene, Arneaud, Sonja L.B., Tatge, Lexus, Otuzoglu, Gupse, Wall, Jordan M., Douglas, Peter M.

    Published in iScience (21-06-2024)
    “…The selective vulnerability of dopaminergic neurons to trauma-induced neurodegeneration is conserved across species, from nematodes to humans. However, the…”
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    Intracellular lipid surveillance by small G protein geranylgeranylation by Watterson, Abigail, Tatge, Lexus, Wajahat, Naureen, Arneaud, Sonja L. B., Solano Fonseca, Rene, Beheshti, Shaghayegh T., Metang, Patrick, Mihelakis, Melina, Zuurbier, Kielen R., Corley, Chase D., Dehghan, Ishmael, McDonald, Jeffrey G., Douglas, Peter M.

    Published in Nature (London) (26-05-2022)
    “…Imbalances in lipid homeostasis can have deleterious effects on health 1 , 2 . Yet how cells sense metabolic demand due to lipid depletion and respond by…”
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    Reduced bone morphogenic protein signaling along the gut–neuron axis by heat shock factor promotes longevity by Arneaud, Sonja L. B., McClendon, Jacob, Tatge, Lexus, Watterson, Abigail, Zuurbier, Kielen R., Madhu, Bhoomi, Gumienny, Tina L., Douglas, Peter M.

    Published in Aging cell (01-09-2022)
    “…Aging is a complex and highly regulated process of interwoven signaling mechanisms. As an ancient transcriptional regulator of thermal adaptation and protein…”
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