Search Results - "Zutter, Mary M."

The Cancer Immunotherapy Biomarker Testing Landscape by Walk, Eric E, Yohe, Sophia L, Beckman, Amy, Schade, Andrew, Zutter, Mary M, Pfeifer, John, Berry, Anna B

“…Cancer immunotherapy provides unprecedented rates of durable clinical benefit to late-stage cancer patients across many tumor types, but there remains a…”
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The current state of omics technologies in the clinical management of asthma and allergic diseases by Donovan, Brittney M., Bastarache, Lisa, Turi, Kedir N., Zutter, Mary M., Hartert, Tina V.

“…To review the state of omics science specific to asthma and allergic diseases and discuss the current and potential applicability of omics in clinical disease…”
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Improving Cancer Diagnosis and Care: Patient Access to High‐Quality Oncologic Pathology by Nass, Sharyl J., Cohen, Michael B., Nayar, Ritu, Zutter, Mary M., Balogh, Erin P., Schilsky, Richard L., Hricak, Hedvig, Elenitoba‐Johnson, Kojo S.J.

“…Drawing on discussions at a workshop hosted by the National Cancer Policy Forum, current challenges in pathology are reviewed and practical steps to facilitate…”
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α2β1 integrin, GPVI receptor, and common FcRγ chain on mouse platelets mediate distinct responses to collagen in models of thrombosis by Marjoram, Robin J, Li, Zhengzhi, He, Li, Tollefsen, Douglas M, Kunicki, Thomas J, Dickeson, S Kent, Santoro, Samuel A, Zutter, Mary M

“…Platelets express the α2β1 integrin and the glycoprotein VI (GPVI)/FcRγ complex, both collagen receptors. Understanding platelet-collagen receptor function has…”
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GPVI and α2β1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow by Sarratt, Kendra L., Chen, Hong, Zutter, Mary M., Santoro, Samuel A., Hammer, Daniel A., Kahn, Mark L.

“…The roles of the 2 major platelet-collagen receptors, glycoprotein VI (GPVI) and integrin α2β1, have been intensely investigated using a variety of methods…”
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β1 Integrin Mediates Internalization of Mammalian Reovirus by MAGINNIS, Melissa S, FORREST, J. Craig, KOPECKY-BROMBERG, Sarah A, DICKESON, S. Kent, SANTORO, Samuel A, ZUTTER, Mary M, NEMEROW, Glen R, BERGELSON, Jeffrey M, DERMODY, Terence S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The contributions of the α2β1 integrin to vascular thrombosis in vivo by He, Li, Pappan, Loretta K., Grenache, David G., Li, Zhengzhi, Tollefsen, Douglas M., Santoro, Samuel A., Zutter, Mary M.

“…The α2β1 integrin serves as a receptor for collagens, laminin, and several other nonmatrix ligands. Many studies have suggested that the α2β1 integrin is a…”
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Novel collectin/C1q receptor mediates mast cell activation and innate immunity by Edelson, Brian T., Stricker, Thomas P., Li, Zhengzhi, Dickeson, S. Kent, Shepherd, Virginia L., Santoro, Samuel A., Zutter, Mary M.

“…Mast cells play a critical role in innate immunity, allergy, and autoimmune diseases. The receptor/ligand interactions that mediate mast cell activation are…”
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Flipping the switch: integrin switching provides metastatic competence by Madamanchi, Aasakiran, Zijlstra, Andries, Zutter, Mary M

“…Integrin switching plays a critical role in the progression to metastatic disease, but the mechanism by which it contributes remains poorly understood. In the…”
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Integrin-mediated adhesion: tipping the balance between chemosensitivity and chemoresistance by Zutter, Mary M

“…The integrin family of extracellular matrix receptors plays an important role in normal development, epithelial morphogenesis, angiogenesis, and in tumor…”
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The α2 integrin subunit-deficient mouse: A multifaceted phenotype including defects of branching morphogenesis and hemostasis by JIANCHUN CHEN, DIACOVO, Thomas G, GRENACHE, David G, SANTORO, Samuel A, ZUTTER, Mary M

“…The α 2 β 1 integrin is a collagen/laminin receptor expressed on platelets, endothelial cells, fibroblasts, and epithelial cells. To define the role of the α 2…”
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Endorepellin Causes Endothelial Cell Disassembly of Actin Cytoskeleton and Focal Adhesions through α2β1 Integrin by Bix, Gregory, Fu, Jian, Gonzalez, Eva M., Macro, Laura, Barker, Amy, Campbell, Shelly, Zutter, Mary M., Santoro, Samuel A., Kim, Jiyeun K., Höök, Magnus, Reed, Charles C., Iozzo, Renato V.

“…Endorepellin, the COOH-terminal domain of the heparan sulfate proteoglycan perlecan, inhibits several aspects of angiogenesis. We provide evidence for a novel…”
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Crosstalk between the α2β1 integrin and c-met/HGF-R regulates innate immunity by McCall-Culbreath, Karissa D., Li, Zhengzhi, Zutter, Mary M.

“…Data from several investigators suggest that the α2β1 integrin, a receptor for collagens, laminins, decorin, E-cadherin, matrix metalloproteinase-1,…”
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Mitigation of oxygen-induced retinopathy in α2β1 integrin-deficient mice by Madamanchi, Aasakiran, Capozzi, Megan, Geng, Ling, Li, Zhengzhi, Friedman, Richard D, Dickeson, S Kent, Penn, John S, Zutter, Mary M

“…The α2β1 integrin plays an important but complex role in angiogenesis and vasculopathies. Published GWAS studies established a correlation between genetic…”
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Data-Driven Iterative Refinement of Bone Marrow Testing Protocols Leads to Progressive Improvement in Cytogenetic and Molecular Test Utilization by Seegmiller, Adam C., Kim, Annette S., Mosse, Claudio A., Shaver, , Aaron C., Thompson, Mary Ann, Li, Shaoying, Head, David R., Zutter, Mary M.

“…Objectives: To determine the effect of iterative refinement of standard ordering protocols on test utilization and results for bone marrow biopsy specimens…”
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α2β1 Integrin by Madamanchi, Aasakiran, Santoro, Samuel A, Zutter, Mary M

“…The α2β1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins [55, 56]. It is…”
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The α2β1 integrin is a metastasis suppressor in mouse models and human cancer by Ramirez, Norma E., Zhang, Zhonghua, Madamanchi, Aasakiran, Boyd, Kelli L., O’Rear, Lynda D., Nashabi, Abudi, Li, Zhengzi, Dupont, William D., Zijlstra, Andries, Zutter, Mary M.

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Proteases, Extracellular Matrix, and Cancer: A Workshop of the Path B Study Section by DeClerck, Yves A, Mercurio, Arthur M, Stack, M. Sharon, Chapman, Harold A, Zutter, Mary M, Muschel, Ruth J, Raz, Avraham, Matrisian, Lynn M, Sloane, Bonnie F, Noel, Agnes, Hendrix, Mary J, Coussens, Lisa, Padarathsingh, Martin

“…The role of the extracellular matrix (ECM) in the tumor microenvironment is not limited to being a barrier against tumor invasion. The ECM is a reservoir of…”
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Limited utility of fluorescence in situ hybridization for common abnormalities of myelodysplastic syndrome at first presentation and follow-up of myeloid neoplasms by Seegmiller, Adam C., Wasserman, Allison, Kim, Annette S., Kressin, Megan K., Marx, Edward R., Zutter, Mary M., Mosse, Claudio A.

“…Abstract Fluorescence in situ hybridization for abnormalities common to myelodysplastic syndrome (MDS FISH) is often used with traditional karyotype in the…”
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α2β1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell–specific manner by Zhang, Zhonghua, Ramirez, Norma E., Yankeelov, Thomas E., Li, Zhengzhi, Ford, Laura E., Qi, Ying, Pozzi, Ambra, Zutter, Mary M.

“…To define the role of the α2β1 integrin in pathologic angiogenesis, we investigated tumor-associated growth and angiogenesis in wild-type and α2-null mice. Our…”
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