Search Results - "Zurkirchen, Luis"
-
1
Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner
Published in Nature communications (16-05-2019)“…The transcription factor Yin Yang 1 (YY1) plays an important role in human disease. It is often overexpressed in cancers and mutations can lead to a congenital…”
Get full text
Journal Article -
2
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
Published in Nature (London) (10-01-2013)“…Adult neural stem and progenitor cells (NSPCs) show high levels of fatty acid synthase (Fasn)-dependent de novo lipogenesis, a process that is controlled by…”
Get full text
Journal Article -
3
Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation
Published in BMC biology (30-11-2015)“…Precise spatiotemporal control of gene expression is essential for the establishment of correct cell numbers and identities during brain development. This…”
Get full text
Journal Article -
4
SPOT14-Positive Neural Stem/Progenitor Cells in the Hippocampus Respond Dynamically to Neurogenic Regulators
Published in Stem cell reports (11-11-2014)“…Proliferation of neural stem/progenitor cells (NSPCs) in the adult brain is tightly controlled to prevent exhaustion and to ensure proper neurogenesis. Several…”
Get full text
Journal Article -
5
Quo vadis: tracing the fate of neural crest cells
Published in Current opinion in neurobiology (01-12-2017)“…•Genetic tools allow single cell lineage-tracing at high resolution.•Single cell lineage-tracing demonstrates multipotency of neural crest cells.•Genetic…”
Get full text
Journal Article -
6
Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation
Published in Cell stem cell (04-04-2019)“…Increasing evidence suggests that cancer cells highjack developmental programs for disease initiation and progression. Melanoma arises from melanocytes that…”
Get full text
Journal Article -
7
Wnt/β‐Catenin Signaling Regulates Sequential Fate Decisions of Murine Cortical Precursor Cells
Published in Stem cells (Dayton, Ohio) (01-01-2015)“…The fate of neural progenitor cells (NPCs) is determined by a complex interplay of intrinsic programs and extrinsic signals, very few of which are known…”
Get full text
Journal Article -
8
Wnt/[beta]-Catenin Signaling Regulates Sequential Fate Decisions of Murine Cortical Precursor Cells
Published in Stem cells (Dayton, Ohio) (01-01-2015)“…The fate of neural progenitor cells (NPCs) is determined by a complex interplay of intrinsic programs and extrinsic signals, very few of which are known…”
Get full text
Journal Article