Search Results - "Zuo, Ze‐Hua"
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Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene
Published in Nature biotechnology (01-06-2017)“…Insertion of the sequence encoding herpes simplex virus 1 thymidine kinase at the breakpoints of fusion genes in cancer cells causes cell death and regression…”
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Cellular stress response 1 down‐regulates the expression of epidermal growth factor receptor and platelet‐derived growth factor receptor through inactivation of splicing factor 3A3
Published in Molecular carcinogenesis (01-02-2017)“…Cellular stress response 1 (CSR1) is a tumor suppressor gene that plays an important role in regulating cell death. In this report, we show that the N‐terminus…”
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Metallothionein 1 h tumour suppressor activity in prostate cancer is mediated by euchromatin methyltransferase 1
Published in The Journal of pathology (01-06-2013)“…Metallothioneins (MTs) are a group of metal binding proteins thought to play a role in the detoxification of heavy metals. Here we showed by microarray and…”
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Oncogenic Activity of Solute Carrier Family 45 Member 2 and Alpha‐Methylacyl‐Coenzyme A Racemase Gene Fusion Is Mediated by Mitogen‐Activated Protein Kinase
Published in Hepatology communications (01-01-2022)“…Chromosome rearrangement is one of the hallmarks of human malignancies. Gene fusion is one of the consequences of chromosome rearrangements. In this report, we…”
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Signal Transducer and Activator of Transcription (STAT)-5A and STAT5B Differentially Regulate Human Mammary Carcinoma Cell Behavior
Published in Endocrinology (Philadelphia) (01-01-2010)“…Increased activation of signal transducer and activator of transcription (STAT)-5 has been reported in various malignancies including mammary carcinoma…”
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Oncogenic Activity of miR-650 in Prostate Cancer Is Mediated by Suppression of CSR1 Expression
Published in The American journal of pathology (01-07-2015)“…Cellular stress response 1 ( CSR1 ) is a tumor suppressor gene whose expression was frequently down-regulated in prostate cancer. The mechanism of its…”
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Discovery and Classification of Fusion Transcripts in Prostate Cancer and Normal Prostate Tissue
Published in The American journal of pathology (01-07-2015)“…Fusion transcript formation is one of the fundamental mechanisms that drives the development of prostate cancer. Because of the advance of high-throughput…”
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Signal Transducer and Activator of Transcription (STAT)-A and STAT5B Differentially Regulate Human Mammary Carcinoma Cell Behavior
Published in Endocrine reviews (01-12-2009)“…Increased signal transducer and activator of transcription (STAT)-5 activation has been reported in various malignancies including mammary carcinoma. However,…”
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Cellular stress response 1 regulates RNA splicing of epidermal growth factor receptor and platelet‐derived growth factor receptor through inactivation of splicing factor 3A3
Published in The FASEB journal (01-04-2016)“…Abstract only Cellular stress response 1 ( CSR1 ) is a tumor suppressor gene that plays an important role in regulating cell death. In this report, we showed…”
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Abstract 4527: Cellular stress response 1 down-regulates the expression of epidermal growth factor receptor and platelet-derived growth factor receptor through inactivation of splicing factor 3A3
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Cellular stress response 1 (CSR1) is a tumor suppressor gene that plays an important role in regulating cell death. In this report, we showed that the…”
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Metallothionein 1h tumour suppressor activity in prostate cancer is mediated by euchromatin methyltransferase 1
Published in The Journal of pathology (01-06-2013)“…Metallothioneins (MTs) are a group of metal binding proteins thought to play a role in the detoxification of heavy metals. Here we showed by microarray and…”
Get full text
Journal Article -
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Targeting genomic rearrangements in tumor cells using Cas9-mediated insertion of a suicide gene
Published in Nature biotechnology (01-05-2017)“…Specifically targeting genomic rearrangements and mutations in tumor cells has remained an elusive goal in cancer therapy. Here, we use Cas9-based genome…”
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When to initiate renal replacement therapy: The trend of dialysis initiation
Published in World journal of nephrology (06-11-2015)“…The timing of renal replacement therapy for patients with end-stage renal disease has been subject to considerable variation. The United States Renal Data…”
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Dynamic changes of HBV DNA in serum and peripheral blood mononuclear cells of chronic hepatitis patients after lamivudine treatment
Published in World journal of gastroenterology : WJG (07-07-2006)“…AIM: To study the dynamic changes of hepatits B virus (HBV) DNA in serum and peripheral blood mononuclear cells (PBMCs) of patients after lamivudine therapy…”
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Inhibitory effect of bladder cancer related protein gene on HeLa cell proliferation
Published in Ai zheng = Aizheng = Chinese journal of cancer (01-07-2006)“…Bladder cancer related protein (BLCAP) gene was found downregulated most in primary cervical cancer tissues using oncogene/tumor suppressor gene microarray…”
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