Search Results - "Zuo, Shiyi"
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Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
Published in Nature communications (19-07-2019)“…Tumor cells are characterized as redox-heterogeneous intracellular microenvironment due to the simultaneous overproduction of reactive oxygen species and…”
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Hybrid chalcogen bonds in prodrug nanoassemblies provides dual redox-responsivity in the tumor microenvironment
Published in Nature communications (24-11-2022)“…Sulfur bonds, especially trisulfide bond, have been found to ameliorate the self-assembly stability of homodimeric prodrug nanoassemblies and could trigger the…”
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3
Synergetic lethal energy depletion initiated by cancer cell membrane camouflaged nano-inhibitor for cancer therapy
Published in Nano research (01-04-2022)“…Mitochondrial bioenergy plays a vital role in the occurrence and development of cancer. Although strategies to impede mitochondrial energy supply have been…”
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Minor change in the length of carbon chain has a great influence on the antitumor effect of paclitaxel-fatty alcohol prodrug nanoassemblies: Small roles, big impacts
Published in Nano research (01-04-2022)“…Prodrug-based nanoassembly emerges as a hopeful way for the efficient delivery of antitumor drugs, with carrier-free structure and ultra-high drug loading…”
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Small changes in the length of diselenide bond-containing linkages exert great influences on the antitumor activity of docetaxel homodimeric prodrug nanoassemblies
Published in Asian journal of pharmceutical sciences (01-05-2021)“…Homodimeric prodrug-based self-assembled nanoparticles, with carrier-free structure and ultrahigh drug loading, is drawing more and more attentions…”
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Iron-doxorubicin prodrug loaded liposome nanogenerator programs multimodal ferroptosis for efficient cancer therapy
Published in Asian journal of pharmceutical sciences (01-11-2021)“…Ferroptosis is a new mode of cell death, which can be induced by Fenton reaction-mediated lipid peroxidation. However, the insufficient H2O2 and high GSH in…”
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The signs of computer tomography combined with artificial intelligence can indicate the correlation between status of consciousness and primary brainstem hemorrhage of patients
Published in Frontiers in neurology (27-03-2023)“…For patients of primary brainstem hemorrhage (PBH), it is crucial to find a method that can quickly and accurately predict the correlation between status of…”
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Generation of two kinds of optical chains with multi-zone fan-shaped filter
Published in Journal of optics (New Delhi) (01-09-2023)“…Based on the vector diffraction theory, two kinds of ultra-long transversally polarized optical chains are obtained by tight focusing double-ring azimuthally…”
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Switchable and Tunable Terahertz Metamaterial Based on Vanadium Dioxide and Photosensitive Silicon
Published in Nanomaterials (Basel, Switzerland) (24-07-2023)“…A switchable and tunable terahertz (THz) metamaterial based on photosensitive silicon and Vanadium dioxide (VO ) was proposed. By using a finite-difference…”
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Probing the Superiority of Diselenium Bond on Docetaxel Dimeric Prodrug Nanoassemblies: Small Roles Taking Big Responsibilities
Published in Small (Weinheim an der Bergstrasse, Germany) (01-11-2020)“…The current state of chemotherapy is far from satisfaction, restricted by the inefficient drug delivery and the off‐target toxicity. Prodrug nanoassemblies are…”
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Biodegradable natural chitosan coating films-based flexible resistive switching memory for transient electronics
Published in Materials science & engineering. B, Solid-state materials for advanced technology (01-09-2023)“…•Ag-doped chitosan as function layer was employed to develop the bio-memristor.•A current–voltage (I-V) hysteresis with a typical capacitive effect is…”
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Prodrug nanoassemblies bridged by Mono-/Di-/Tri-sulfide bonds: Exploration is for going further
Published in Nano today (01-06-2022)“…Sulfur bonds, including thioether bond and disulfide bond, have been widely used to develop tumor redox-responsive drug delivery systems. Recently, trisulfide…”
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Trisulfide bond-mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity
Published in Science advances (01-11-2020)“…Rational design of nanoparticulate drug delivery systems (nano-DDS) for efficient cancer therapy is still a challenge, restricted by poor drug loading, poor…”
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Double transformation of the nonlinear absorption in silver nanoparticles
Published in Optics express (07-11-2022)“…The nonlinear absorption of 40 nm Ag nanoparticles (Ag NPs) was investigated using open aperture (OA) Z-scan technique at 532 nm. Experiments show that the…”
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Nano-immunotherapy for each stage of cancer cellular immunity: which, why, and what?
Published in Theranostics (01-01-2021)“…Immunotherapy provides a new avenue for combating cancer. Current research in anticancer immunotherapy is primary based on T cell-mediated cellular immunity,…”
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Structure–Activity Relationship of pH-Sensitive Doxorubicin-Fatty Acid Prodrug Albumin Nanoparticles
Published in Nano letters (22-02-2023)“…Albumin has emerged as a versatile drug carrier. To harness albumin as a carrier for doxorubicin (DOX), we synthesized three acid-labile DOX prodrugs using…”
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Satellite‐Type Sulfur Atom Distribution in Trithiocarbonate Bond‐Bridged Dimeric Prodrug Nanoassemblies: Achieving Both Stability and Activatability
Published in Advanced materials (Weinheim) (01-01-2024)“…Homodimeric prodrug nanoassemblies (HDPNs) hold promise for improving the delivery efficiency of chemo‐drugs. However, the key challenge lies in designing…”
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Revealing the impact of modified modules flexibility on gemcitabine prodrug nanoassemblies for effective cancer therapy
Published in Journal of colloid and interface science (01-01-2025)“…[Display omitted] Prodrug nanoassemblies combine the advantages of prodrug strategies and nanotechnology have been widely utilized for delivering antitumor…”
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Cabazitaxel prodrug nanoassemblies with branched chain modifications: Narrowing the gap between efficacy and safety
Published in Journal of controlled release (01-08-2023)“…The clinical application of cabazitaxel (CTX) is restricted by severe dose-related toxicity, failing to considering therapeutic efficacy and safety together…”
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Cholesterol sulfate-mediated ion-pairing facilitates the self-nanoassembly of hydrophilic cationic mitoxantrone
Published in Journal of colloid and interface science (01-09-2024)“…[Display omitted] Hydrophilic cationic drugs such as mitoxantrone hydrochloride (MTO) pose a significant delivery challenge to the development of nanodrug…”
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