Search Results - "Zuo, Sai"

Novel compound ZCJ14, a gefitinib analog, exhibited prominent anti-cancer effect among several cancer cell lines by Wang, Jin, Yan, Ping-ping, Wang, Hong-ying, Zuo, Sai-jie, Zhang, San-qi, Cao, Yong-xiao, Cao, Lei

“…ZCJ14, a gefitinib analog, exhibited prominent anti-cancer effect both in vitro and in vivo. The present study aims to investigate the inhibitory effects of…”
Get full text

Quantitative analysis and pharmacokinetic study of a novel diarylurea EGFR inhibitor (ZCJ14) in rat plasma using a validated LC-MS/MS method by Zuo, Sai-Jie, Cheng, Xiao-Liang, Liu, Dong-Zheng, Feng, Wei-Yi, Cao, Yong-Xiao, Zhang, San-Qi

“…1-(4-(Pyrrolidin-1-yl-methyl)phenyl)-3-(4-((3-(trifluoromethyl) phenyl)amino)quinazolin-6-yl)urea (ZCJ14), a novel epidermal growth factor receptor (EGFR)…”
Get full text

Structural modification and antihypertensive activity study of formononetin derivatives by Zuo, Sai-Jie, Ma, Dong-Lai, Li, Jing, Guo, Qiu-Hong, Zhou, Li

“…A series of formononetin derivatives with substituted benzyloxy groups on the 4′ position of isoflavone were designed and synthesized. Their vasodilative…”
Get full text

Abnormalities of white matter microstructure in unmedicated obsessive-compulsive disorder and changes after medication by Fan, Qing, Yan, Xu, Wang, Jijun, Chen, Ying, Wang, Xuemei, Li, Chunbo, Tan, Ling, You, Chao, Zhang, Tianhong, Zuo, Sai, Xu, Dongrong, Chen, Kemin, Finlayson-Burden, Jodie Marie, Xiao, Zeping

“…Abnormalities of myelin integrity have been reported in obsessive-compulsive disorder (OCD) using multi-parameter maps of diffusion tensor imaging (DTI)…”
Get full text

Cultural Perspectives on Tobacco Use and Cessation Among Chinese American Immigrants: A Community-Engaged Qualitative Study by Katigbak, Carina, Maglalang, Dale Dagar, Chao, Ying-Yu, Au, Helen, Liang, Winnie, Zuo, Sai

“…Introduction: Tobacco use is a preventable cause of death among ethnic minorities. Chinese Americans have high smoking rates and underutilize evidence-based…”
Get full text

Synthesis and antitumor activity evaluation of PI3K inhibitors containing 3-substituted quinazolin-4(3H)-one moiety by Zhang, Hao, Xin, Min-Hang, Xie, Xiao-Xiao, Mao, Shuai, Zuo, Sai-Jie, Lu, She-Min, Zhang, San-Qi

“…[Display omitted] In present study, a series of N-(2-methoxy-5-(3-substituted quinazolin-4(3H)-one-6-yl)-pyridin-3-yl)phenylsulfonamide were synthesized. Their…”
Get full text

Combination of 4-anilinoquinazoline, arylurea and tertiary amine moiety to discover novel anticancer agents by Zuo, Sai-Jie, Zhang, Sai, Mao, Shuai, Xie, Xiao-Xiao, Xiao, Xue, Xin, Min-Hnag, Xuan, Wei, He, Yuan-Yuan, Cao, Yong-Xiao, Zhang, San-Qi

“…[Display omitted] In present study, 4-anilinoquinazolines scaffold, arylurea and tertiary amine moiety were combined to design, synthesize gefitinib analogs…”
Get full text

Vasodilation and hypotension of a novel 3-benzylquinazolin- 4(3H)-one derivative via the inhibition of calcium flux by Sen Li, Zuo, Sai-jie, Cao, Lei, Liu, Dong-zheng, Zhang, San-qi, Cao, Yong-xiao

“…A novel 3-benzylquinazolin-4(3H)-one derivative Z32, namely 6,7-dimethoxy-3-(3-chloro-4-(4-fluorobenzyloxy)benzyl)quinazolin-4(3H)-one was synthesized. The…”
Get full text

Discovery of novel 3-benzylquinazolin-4(3H)-ones as potent vasodilative agents by Zuo, Sai-Jie, Li, Sen, Yu, Rui-Hong, Zheng, Guo-Xun, Cao, Yong-Xiao, Zhang, San-Qi

“…In the present study, a series of 3-benzylquinazolin-4(3H)-ones were synthesized and characterized. Their vasodilative effects were evaluated by wire myograph…”
Get full text

An HPLC method for the determination of a novel anti-hypertension agent 6,7-dimethoxy-3-[4-(4-fluorobenzyloxy)-3-methoxyphenylmethyl]quinazolin-4(3H)-one in rat plasma: application to pharmacokinetic study by Chang, Rui-Miao, Zeng, Ai-Guo, Du, Wei, Xu, Xin-Ya, Zuo, Sai-Jie, Chang, Chun, Fu, Qiang

“…6,7‐Dimethoxy‐3‐[4‐(4‐fluorobenzyloxy)‐3‐methoxyphenylmethyl] quinazolin‐4(3H)‐one (DFMQ‐19), a novel analog of 3‐benzylquinazolin‐4(3H)‐ones, may be…”
Get full text

Evaluations of treatment efficacy of depression from perspective of both patients’ symptoms and general sense of mental health and wellbeing: A large scale, multi-centered, longitudinal study in China by Zeng, Qingzhi, Wang, Wei Chun, Fang, Yiru, Mellor, David, Mccabe, Marita, Byrne, Linda, Zuo, Sai, Xu, Yifeng

“…Abstract Relying on the absence, presence of level of symptomatology may not provide an adequate indication of the effects of treatment for depression, nor…”
Get full text

Association between SREBF2 gene polymorphisms and metabolic syndrome in clozapine-treated patients with schizophrenia by Yang, Lin, Chen, Jianhua, Liu, Dengtang, Yu, Shunying, Cong, Enzhao, Li, Yan, Wu, Haisu, Yue, Ying, Zuo, Sai, Wang, Yan, Liang, Shiqiao, Shi, Yongyong, Shi, Shenxun, Xu, Yifeng

“…Patients with schizophrenia using antipsychotics often develop metabolic side effects, especially with clozapine. Previous studies indicated that…”
Get full text

Sleep problems among clinically depressed adults in China by Zuo, Sai, McCabe, Marita P, Mellor, David, Xu, Yifeng

“…The aim of the study was to explore which variables predict poor sleep among clinically depressed Chinese adults. In total, 100 participants were recruited…”
Get more information

An HPLC method for the determination of a novel anti-hypertension agent 6,7-dimethoxy-3-[4-(4-fluorobenzyloxy)-3-methoxyphenylmethyl]quina z olin-4(3H)-one in rat plasma: application to pharmacokinetic study by Chang, Rui-Miao, Zeng, Ai-Guo, Du, Wei, Xu, Xin-Ya, Zuo, Sai-Jie, Chang, Chun, Fu, Qiang

“…6,7-Dimethoxy-3-[4-(4-fluorobenzyloxy)-3-methoxyphenylmethyl] quinazolin-4(3H)-one (DFMQ-19), a novel analog of 3-benzylquinazolin-4(3H)-ones, may be…”
Get full text

An HPLC method for the determination of a novel anti-hypertension agent 6,7-dimethoxy-3-(4-(4-fluorobenzyloxy)-3-methoxyphenylmethyl)quinazolin-4(3H)-one in rat plasma: application to pharmacokinetic study by Chang, Rui-Miao, Zeng, Ai-Guo, Du, Wei, Xu, Xin-Ya, Zuo, Sai-Jie, Chang, Chun, Fu, Qiang

“…6,7-dimethoxy-3-(4-(4-fluorobenzyloxy)-3-methoxyphenylmethyl) quinazolin-4(3H)-one (DFMQ-19), a novel analogue of 3-benzylquinazolin-4(3H)-ones, may be…”
Get full text

Social support and clinical depression in China by Zuo, Sai, Mellor, David, McCabe, Marita, Xu, Yifeng

“…Introduction It has been recognised for many years that in Western contexts social support is associated with depression. However, relatively few studies have…”
Get full text

Social support and clinical depression in C hina by Zuo, Sai, Mellor, David, McCabe, Marita, Xu, Yifeng

Get full text

Symptom severity is more closely associated with social functioning status in inpatients with schizophrenia than cognitive deficits by Zuo, Sai, Byrne, Linda K, Peng, Daihui, Mellor, David, McCabe, Marita, Zhang, Jie, Huang, Jia, Xu, Yifeng

“…Prior research has determined that impairment in neurocognition and psychiatric symptoms contribute to reduced occupational and social functioning in…”
Get full text

症状严重程度比认知缺损更与精神分裂症住院患者的社会功能状况密切相关(英文) by 左赛 Linda K.BYRNE 彭代辉 David MELLOR Marita McCABE 张洁 黄佳 徐一峰

“…背景以往研究表明精神分裂症患者的神经认知缺损和精神病性症状会导致其职业和社会功能降低。目的评估中国精神分裂症男性住院患者的神经认知和精神病性症状与社会心理功能之间的关系。方法选取上海市精神卫生中心的51例住院男性精神分裂症患者,其中40例患者最终完成了个体和社会功能量表(Personal and Social…”
Get full text

症状严重程度比认知缺损更与精神分裂症住院患者的社会功能状况密切相关（英文） by 左赛 Linda K.BYRNE 彭代辉 David MELLOR Marita McCABE 张洁 黄佳 徐一峰

“…背景以往研究表明精神分裂症患者的神经认知缺损和精神病性症状会导致其职业和社会功能降低。目的评估中国精神分裂症男性住院患者的神经认知和精神病性症状与社会心理功能之间的关系。方法选取上海市精神卫生中心的51例住院男性精神分裂症患者,其中40例患者最终完成了个体和社会功能量表（Personal and Social…”
Get full text