Search Results - "Zuo, Lingjun"

CNR1 Variation Modulates Risk for Drug and Alcohol Dependence by Zuo, Lingjun, Kranzler, Henry R, Luo, Xingguang, Covault, Jonathan, Gelernter, Joel

“…Background Human cannabinoid receptor 1 (CB1), which is encoded by the CNR1 gene, may play a role in the development of substance dependence (SD). Following…”
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Genome-wide association studies of maximum number of drinks by Pan, Yue, Luo, Xingguang, Liu, Xuefeng, Wu, Long-Yang, Zhang, Qunyuan, Wang, Liang, Wang, Weize, Zuo, Lingjun, Wang, Ke-Sheng

“…Abstract Maximum number of drinks (MaxDrinks) defined as “Maximum number of alcoholic drinks consumed in a 24-h period” is an intermediate phenotype that is…”
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CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case–control structured association study by Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Wang, Shuang, Blumberg, Hilary P., Gelernter, Joel

“…Cholinergic muscarinic 2 receptor (CHRM2) is implicated in memory and cognition, functions impaired in many neuropsychiatric disorders. Wang et al. [Wang,…”
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Transperitoneal vs retroperitoneal laparoscopic radical nephrectomy: a double-arm, parallel-group randomized clinical trial by Liu, Junyao, Zhang, Bin, Qi, Peng, Ren, Xiaowei, Zheng, Duo, He, Yang, Zheng, Xu, Yue, Zhongjin, Li, Ye, Yang, Ningqiang, Wang, Zhiping, Bao, Junsheng, Tian, Junqiang, Yang, Li, Zhai, Zhenxing, Zuo, Lingjun, Hou, Zizhen, Wang, Jiaji, Wang, Wei, Chang, Hong, Ma, Junhai, Zhang, Yunxin, Dong, Zhichun, Dong, Zhilong, Zhong, Ganping, Cheng, Hui, Lei, Pengyuan, Li, Zhongming, Wu, GongJin, Shang, Panfeng

“…To compare the outcomes of patients undergoing Retroperitoneal laparoscopic Radical nephrectomy (RLRN) and Transperitoneal laparoscopic Radical nephrectomy…”
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Diplotype Trend Regression Analysis of the ADH Gene Cluster and the ALDH2 Gene: Multiple Significant Associations with Alcohol Dependence by Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Wang, Shuang, Schork, Nicholas J., Gelernter, Joel

“…The set of alcohol-metabolizing enzymes has considerable genetic and functional complexity. The relationships between some alcohol dehydrogenase ( ADH) and…”
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Cognitive Function, Plasma MnSOD Activity, and MnSOD Ala-9Val Polymorphism in Patients With Schizophrenia and Normal Controls by ZHANG, Xiang Y, CHEN, Da C, XIU, Mei H, YANG, Fu D, YUNLONG TAN, XINGGUANG LUO, LINGJUN ZUO, KOSTEN, Therese A, KOSTEN, Thomas R

“…Excessive reactive oxygen species are thought to produce oxidative damage that underlies neurodegeneration and cognitive impairment in several disorders…”
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KTN1 Variants Underlying Putamen Gray Matter Volumes and Parkinson's Disease by Mao, Qiao, Wang, Xiaoping, Chen, Bin, Fan, Longhua, Wang, Shuhong, Zhang, Yong, Lin, Xiandong, Cao, Yuping, Wu, Yun-Cheng, Ji, Jiawu, Xu, Jianying, Zheng, Jianming, Zhang, Huihao, Zheng, Chengchou, Chen, Wenzhong, Cheng, Wenhong, Luo, Xingqun, Wang, Kesheng, Zuo, Lingjun, Kang, Longli, Li, Chiang-Shan R, Luo, Xingguang

“…Selective loss of dopaminergic neurons and diminished putamen gray matter volume (GMV) represents a central feature of Parkinson's disease (PD). Recent studies…”
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A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study by Zuo, Lingjun, Zhang, Clarence K, Wang, Fei, Li, Chiang-Shan R, Zhao, Hongyu, Lu, Lingeng, Zhang, Xiang-Yang, Lu, Lin, Zhang, Heping, Zhang, Fengyu, Krystal, John H, Luo, Xingguang

“…Several genome-wide association studies (GWASs) reported tens of risk genes for alcohol dependence, but most of them have not been replicated or confirmed by…”
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Association of rare PTP4A1-PHF3-EYS variants with alcohol dependence by Zuo, Lingjun, Zhang, Xiangyang, Deng, Hong-Wen, Luo, Xingguang

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BDNF Val66Met variant and smoking in a Chinese population by Zhang, Xiang Yang, Chen, Da Chun, Xiu, Mei Hong, Luo, Xingguang, Zuo, Lingjun, Haile, Colin N, Kosten, Therese A, Kosten, Thomas R

“…Several recent studies have supported the hypothesis that brain-derived neurotrophic factor (BDNF), a member of the neurotrophic factor family, might be…”
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ADH4 gene variation is associated with alcohol dependence and drug dependence in european americans : Results from HWD tests and case-control association studies by XINGGUANG LUO, KRANZLER, Henry R, LINGJUN ZUO, LAPPALAINEN, Jaakko, YANG, Bao-Zhu, GELERNTER, Joel

“…The alcohol dehydrogenase (ADH) family constitutes one of the key sets of enzymes responsible for the oxidation of alcohol. The ADH4 gene, an important member…”
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Rare ADH Variant Constellations are Specific for Alcohol Dependence by LINGJUN ZUO, HEPING ZHANG, FENGYU ZHANG, DENG, Hong-Wen, XINGGUANG LUO, MALISON, Robert T, LI, Chiang-Shan R, ZHANG, Xiang-Yang, FEI WANG, LINGENG LU, LIN LU, XIAOPING WANG, KRYSTAL, John H

“…Some of the well-known functional alcohol dehydrogenase (ADH) gene variants (e.g. ADH1B*2, ADH1B*3 and ADH1C*2) that significantly affect the risk of alcohol…”
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Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence by Zuo, Lingjun, Zhang, Fengyu, Zhang, Heping, Zhang, Xiang-Yang, Wang, Fei, Li, Chiang-Shan R., Lu, Lingeng, Hong, Jiang, Lu, Lin, Krystal, John, Deng, Hong-Wen, Luo, Xingguang

“…The present study searched for replicable risk genomic regions for alcohol and nicotine co‐dependence using a genome‐wide association strategy. The data…”
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The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation by Zuo, Lingjun, Luo, Xingguang, Krystal, John H, Cramer, Joyce, Charney, Dennis S, Gelernter, Joel

“…OBJECTIVEThe prototypical atypical antipsychotic agent, clozapine, is more efficacious for refractory schizophrenia than the ‘typical’ antipsychotics, but the…”
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Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans by Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Wang, Shuang, Schork, Nicholas J., Gelernter, Joel

“…Drug dependence (DD) is commonly co-morbid with alcohol dependence (AD). Many studies have also shown common genetic risk factors for these disorders. We…”
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Association of functional dopamine-beta-hydroxylase (DBH) 19 bp insertion/deletion polymorphism with smoking severity in male schizophrenic smokers by Zhang, Xiang Yang, Chen, Da Chun, Xiu, Mei Hong, Hui, Li, Liu, Haibo, Luo, Xingguang, Zuo, Lingjun, Zhang, Huiping, Kosten, Therese A, Kosten, Thomas R

“…Abstract Recent evidence suggests that a dopamine beta-hydroxylase (DBH) polymorphism may play a role in determining an individual's predisposition to…”
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ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies by Luo, Xingguang, Kranzler, Henry R, Zuo, Lingjun, Yang, Bao-zhu, Lappalainen, Jaakko, Gelernter, Joel

“…We found strong associations between ADH4 gene variation and alcohol and drug dependence by the Hardy–Weinberg Disequilibrium (HWD) test and case–control…”
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Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations by Luo, Xingguang, Zuo, Lingjun, Kranzler, Henry, Zhang, Huiping, Wang, Shuang, Gelernter, Joel

“…Personality traits are among the most complex quantitative traits. Certain personality traits are associated with substance dependence (SD); genetic factors…”
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Long noncoding RNAs in psychiatric disorders by Zuo, Lingjun, Tan, Yunlong, Wang, Zhiren, Wang, Ke-Sheng, Zhang, Xiangyang, Chen, Xiangning, Li, Chiang-Shan R., Wang, Tong, Luo, Xingguang

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ADH7 variation modulates extraversion and conscientiousness in substance-dependent subjects by Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Zhang, Huiping, Wang, Shuang, Gelernter, Joel

“…Human personality traits have been closely linked to substance dependence (SD), and are partially genetically determined. Recently, associations between…”
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