Search Results - "Zuo, Huanyan"
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BMP2-dependent gene regulatory network analysis reveals Klf4 as a novel transcription factor of osteoblast differentiation
Published in Cell death & disease (19-02-2021)“…Transcription factors (TFs) regulate the expression of target genes, inducing changes in cell morphology or activities needed for cell fate determination and…”
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CREB3L1 deficiency impairs odontoblastic differentiation and molar dentin deposition partially through the TMEM30B
Published in International journal of oral science (10-10-2024)“…Odontoblasts are primarily responsible for synthesizing and secreting extracellular matrix proteins, which are crucial for dentinogenesis. Our previous…”
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Role of the Demethylase AlkB Homolog H5 in the Promotion of Dentinogenesis
Published in Frontiers in physiology (15-06-2022)“…Dentinogenesis is a key process in tooth formation and is regulated by a series of pre- and post-transcriptional regulations. N6-methyl-adenosine (m 6 A),…”
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Chromatin conformation of human oral epithelium can identify orofacial cleft missing functional variants
Published in International journal of oral science (25-08-2022)“…Genome-wide association studies (GWASs) are the most widely used method to identify genetic risk loci associated with orofacial clefts (OFC). However, despite…”
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Chromatin Accessibility Predetermines Odontoblast Terminal Differentiation
Published in Frontiers in cell and developmental biology (25-11-2021)“…Embryonic development and stem cell differentiation are orchestrated by changes in sequential binding of regulatory transcriptional factors to their motifs…”
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Xbp1 promotes odontoblastic differentiation through modulating mitochondrial homeostasis
Published in The FASEB journal (15-04-2024)“…Odontoblast differentiation depends on the orderly recruitment of transcriptional factors (TFs) in the transcriptional regulatory network. The depletion of…”
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Loss of MMP9 disturbs cranial suture fusion via suppressing cell proliferation, chondrogenesis and osteogenesis in mice
Published in Matrix biology (01-12-2024)“…•Mmp9 expression was specifically elevated during fusion of posterior frontal (PF) suture compared with other patent sutures in mice.•MMP9 depletion disturbed…”
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Coordinated expression of p300 and HDAC3 upregulates histone acetylation during dentinogenesis
Published in Journal of cellular biochemistry (01-03-2020)“…Cellular differentiation is caused by highly controlled modifications in the gene expression but rarely involves a change in the DNA sequence itself. Histone…”
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Dynamic patterns of histone lactylation during early tooth development in mice
Published in Journal of molecular histology (01-12-2023)“…Histone lactylation on its lysine (K) residues has been reported to have indispensable roles in lung fibrosis, embryogenesis, neural development, inflammation,…”
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RUNX2 co‐operates with EGR1 to regulate osteogenic differentiation through Htra1 enhancers
Published in Journal of cellular physiology (01-11-2020)“…Runt‐related transcription factor 2 (Runx2) has been shown to regulate osteoblast differentiation by directly or indirectly regulating numerous…”
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Phosphorylation of ATF2 promotes odontoblastic differentiation via intrinsic HAT activity
Published in Journal of genetics and genomics (01-07-2023)“…Mouse dental papilla cells (mDPCs) are cranial neural crest-derived dental mesenchymal cells that give rise to dentin-secreting odontoblasts after the bell…”
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12
Chromatin conformation of human oral epithelium can identify orofacial cleft missing functional variants
Published in 国际口腔科学杂志(英文版) (2022)Get full text
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