Search Results - "Zunino, Susan J"

Effects of dietary strawberry powder on blood lipids and inflammatory markers in obese human subjects by Zunino, Susan J., Parelman, Mardi A., Freytag, Tammy L., Stephensen, Charles B., Kelley, Darshan S., Mackey, Bruce E., Woodhouse, Leslie R., Bonnel, Ellen L.

“…Obesity is a strong risk factor for the development of CVD, hypertension and type 2 diabetes. The overall goal of the present pilot study was to feed…”
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Physiological Levels of Resveratrol Metabolites are Ineffective as Anti-Leukemia Agents Against Jurkat Leukemia Cells by Zunino, Susan J, Storms, David H

“…Dietary resveratrol is metabolically transformed in vivo by the intestine and liver to produce resveratrol glucuronides and sulfates in humans. Little is known…”
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Dietary strawberry powder reduces blood glucose concentrations in obese and lean C57BL/6 mice, and selectively lowers plasma C-reactive protein in lean mice by Parelman, Mardi A., Storms, David H., Kirschke, Catherine P., Huang, Liping, Zunino, Susan J.

“…The purpose of the present study was to test the anti-inflammatory and blood glucose (BG)-regulating capacity of strawberries in a mouse model of diet-induced…”
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Resveratrol increases phagocytosis and lipopolysaccharide-induced interleukin-1β production, but decreases surface expression of Toll-like receptor 2 in THP-1 monocytes by Zunino, Susan J., Hwang, Daniel H., Huang, Shurong, Storms, David H.

“…•Resveratrol increases phagocytic activity of monocytes.•Resveratrol increases lipopolysaccharide-induced IL-1β production in monocytes.•Resveratrol decreases…”
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Dietary grape powder increases IL-1β and IL-6 production by lipopolysaccharide-activated monocytes and reduces plasma concentrations of large LDL and large LDL-cholesterol particles in obese humans by Zunino, Susan J., Peerson, Jan M., Freytag, Tammy L., Breksa, Andrew P., Bonnel, Ellen L., Woodhouse, Leslie R., Storms, David H.

“…Obese individuals are at an increased risk of developing CVD, hypertension, type 2 diabetes, and bacterial and viral infections when compared with the…”
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Postprandial Inflammatory Responses and Free Fatty Acids in Plasma of Adults Who Consumed a Moderately High-Fat Breakfast with and without Blueberry Powder in a Randomized Placebo-Controlled Trial by Ono-Moore, Kikumi D, Snodgrass, Ryan G, Huang, Shurong, Singh, Shamsher, Freytag, Tammy L, Burnett, Dustin J, Bonnel, Ellen L, Woodhouse, Leslie R, Zunino, Susan J, Peerson, Janet M, Lee, Joo Young, Rutledge, John C, Hwang, Daniel H

“…Saturated fatty acids (FAs) released from triglyceride-rich lipoproteins (TGRLs) activate Toll-like receptor 2 (TLR-2) and induce the expression of…”
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Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice by Zunino, Susan J, Storms, David H, Stephensen, Charles B

“…Type I juvenile diabetes mellitus is characterized by the infiltration of activated T lymphocytes and monocytes into the islets of Langerhans of the pancreas,…”
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Efficient eukaryotic expression of fluorescent scFv fusion proteins directed against CD antigens for FACS applications by Peipp, Matthias, Saul, Domenica, Barbin, Karin, Bruenke, Joerg, Zunino, Susan J., Niederweis, Michael, Fey, Georg H.

“…Two sets of expression vectors were constructed that permitted the efficient expression of single-chain Fv fragments (scFvs) fused N-terminally to an enhanced…”
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Resveratrol alters proliferative responses and apoptosis in human activated B lymphocytes in vitro by Zunino, Susan J, Storms, David H

“…We hypothesized that the phytochemicals resveratrol, quercetin, and kaempferol would modulate B lymphocyte proliferation, Ig synthesis, and apoptosis after…”
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Resveratrol-3-O-glucuronide and resveratrol-4′-O-glucuronide reduce DNA strand breakage but not apoptosis in Jurkat T cells treated with camptothecin by Zunino, Susan J, Storms, David H

“…Resveratrol has been reported to inhibit or induce DNA damage, depending upon the type of cell and the experimental conditions. Dietary resveratrol is present…”
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Resveratrol-induced apoptosis is enhanced in acute lymphoblastic leukemia cells by modulation of the mitochondrial permeability transition pore by Zunino, Susan J., Storms, David H.

“…We have previously shown that resveratrol can induce apoptotic cell death in cell lines established from patients with acute lymphoblastic leukemia (ALL)…”
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Parthenolide induces significant apoptosis and production of reactive oxygen species in high-risk pre-B leukemia cells by Zunino, Susan J, Ducore, Jonathan M, Storms, David H

“…Abstract We investigated whether parthenolide, the principal bioactive component of the herb feverfew ( Tanacetum parthenium ) induced apoptosis in pre-B acute…”
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Dietary strawberries increase the proliferative response of CD3/CD28-activated CD8+ T cells and the production of TNF-α in lipopolysaccharide-stimulated monocytes from obese human subjects by Zunino, Susan J., Storms, David H., Freytag, Tammy L., Mackey, Bruce E., Zhao, Ling, Gouffon, Julia S., Hwang, Daniel H.

“…Obesity increases the risk of developing bacterial and viral infections compared with normal weight. In a 7-week double-blind, randomised, cross-over trial,…”
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Increased cytokine production by monocytes from human subjects who consumed grape powder was not mediated by differences in dietary intake patterns by Zunino, Susan J, Keim, Nancy L, Kelley, Darshan S, Bonnel, Ellen L, Souza, Elaine C, Peerson, Janet M

“…Abstract Recently, in a randomized, double-blind cross-over study, we reported that consumption of grape powder by obese human subjects increased the…”
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Citrus limonin glucoside supplementation decreased biomarkers of liver disease and inflammation in overweight human adults by Kelley, Darshan S., Adkins, Yuriko C., Zunino, Susan J., Woodhouse, Leslie R., Bonnel, Ellen L., Breksa, Andrew P., Manners, Gary D., Mackey, Bruce E.

“…•Double-blind, cross over trial to study health effects of LG in overweight adults.•Beverages containing LG had no specific adverse effects.•LG lowered levels…”
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Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model by ZUNINO, Susan J, STORMS, David H, NEWMAN, John W, PEDERSEN, Theresa L, KEEN, Carl L, DUCORE, Jonathan M

“…The efficacy of resveratrol as a preventive agent against the growth of t(4;11) acute lymphoblastic leukemia (ALL) was evaluated in NOD.CB17-Prkdcscid/J mice…”
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Dietary resveratrol does not delay engraftment, sensitize to vincristine or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice by ZUNINO, SUSAN J, STORMS, DAVID H, NEWMAN, JOHN W, PEDERSEN, THERESA L, KEEN, CARL L, DUCORE, JONATHAN M

“…Acute lymphoblastic leukemia (ALL) with translocation t(4;11) is a high-risk leukemia found in 60-85% of infants with ALL and is often refractory to…”
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Dietary supplementation with purified citrus limonin glucoside does not alter ex vivo functions of circulating T lymphocytes or monocytes in overweight/obese human adults by Zunino, Susan J, Storms, David H, Freytag, Tammy L, Adkins, Yuriko C, Bonnel, Ellen L, Woodhouse, Leslie R, Breksa, Andrew P, Manners, Gary D, Mackey, Bruce E, Kelley, Darshan S

“…Abstract Overweight/obesity is associated with chronic inflammation and impairs both innate and adaptive immune responses. Limonoids found in citrus fruits…”
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Parthenolide treatment activates stress signaling proteins in high-risk acute lymphoblastic leukemia cells with chromosomal translocation t(4;11) by ZUNINO, Susan J, STORMS, David H, DUCORE, Jonathan M

“…Parthenolide, the principal bio-active component of the herb feverfew (Tanacetum parthenium), has shown anti-leukemic activity. We evaluated the cell cycle…”
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Novel in vivo model of inducible multi-drug resistance in acute lymphoblastic leukemia with chromosomal translocation t(4;11) by Zunino, Susan J, Storms, David H, Ducore, Jonathan M

“…Abstract Acute lymphoblastic leukemia (ALL) with translocation t(4;11) is found in 60–85% of infants with ALL and is often refractory to conventional…”
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