Search Results - "Zummo, Francesco Paolo"
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Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver
Published in Molecular systems biology (01-05-2020)“…Liver injury triggers adaptive remodeling of the hepatic transcriptome for repair/regeneration. We demonstrate that this involves particularly profound…”
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Protective effects of lemon nanovesicles: evidence of the Nrf2/HO-1 pathway contribution from in vitro hepatocytes and in vivo high-fat diet-fed rats
Published in Biomedicine & pharmacotherapy (01-11-2024)“…The cross-talk between plant-derived nanovesicles (PDNVs) and mammalian cells has been explored by several investigations, underlining the capability of these…”
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Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response
Published in Cells (Basel, Switzerland) (13-09-2018)“…Hepatic stellate cells (HSCs) serve as the main body storage compartment for vitamin A through retinyl ester (RE)-filled lipid droplets (LDs). Upon liver…”
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4
Correlation of Metabolic Syndrome with Redox Homeostasis Biomarkers: Evidence from High-Fat Diet Model in Wistar Rats
Published in Antioxidants (30-12-2022)“…Metabolic Syndrome (MetS) is an extremely complex disease. A non-balanced diet such as high-fat diet (HFD) induces metabolic dysfunction that could modify…”
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NF-kB Regulation and the Chaperone System Mediate Restorative Effects of the Probiotic Lactobacillus fermentum LF31 in the Small Intestine and Cerebellum of Mice with Ethanol-Induced Damage
Published in Biology (Basel, Switzerland) (01-11-2023)“…Probiotics are live microorganisms that yield health benefits when consumed, generally by improving or restoring the intestinal flora (microbiota) as part of…”
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6
Nanovesicular Mediation of the Gut-Brain Axis by Probiotics: Insights into Irritable Bowel Syndrome
Published in Biology (Basel, Switzerland) (01-05-2024)“…Dysbiosis, influenced by poor diet or stress, is associated with various systemic diseases. Probiotic supplements are recognized for stabilizing gut microbiota…”
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"Golden" Tomato Consumption Ameliorates Metabolic Syndrome: A Focus on the Redox Balance in the High-Fat-Diet-Fed Rat
Published in Antioxidants (18-05-2023)“…Tomato fruits defined as "golden" refer to a food product harvested at an incomplete ripening stage with respect to red tomatoes at full maturation. The aim of…”
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Probiotics as Potential Therapeutic Agents: Safeguarding Skeletal Muscle against Alcohol-Induced Damage through the Gut-Liver-Muscle Axis
Published in Biomedicines (01-02-2024)“…Probiotics have shown the potential to counteract the loss of muscle mass, reduce physical fatigue, and mitigate inflammatory response following intense…”
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9
A time- and space-resolved nuclear receptor atlas in mouse liver
Published in Journal of molecular endocrinology (01-07-2023)“…The functional versatility of the liver is paramount for organismal homeostasis. Adult liver functions are controlled by a tightly regulated transcription…”
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Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin
Published in JCI insight (06-07-2017)“…Nonalcoholic fatty liver disease prevalence is soaring with the obesity pandemic, but the pathogenic mechanisms leading to the progression toward active…”
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NF-kB Regulation and the Chaperone System Mediate Restorative Effects of the Probiotic ILactobacillus fermentum/I LF31 in the Small Intestine and Cerebellum of Mice with Ethanol-Induced Damage
Published in Biology (Basel, Switzerland) (01-11-2023)“…Probiotics are live microorganisms that offer health benefits, primarily by improving the gut microbiota. A study involving mice explored the impact of…”
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12
Na + /Ca 2+ Exchanger a Druggable Target to Promote β -Cell Proliferation and Function
Published in Journal of the Endocrine Society (01-07-2018)“…An important feature of type 2 diabetes is a decrease in -cell mass. Therefore, it is essential to find new approaches to stimulate -cell proliferation. We…”
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Na+/Ca2+ Exchanger a Druggable Target to Promote β-Cell Proliferation and Function
Published in Journal of the Endocrine Society (01-07-2018)“…Abstract An important feature of type 2 diabetes is a decrease in β-cell mass. Therefore, it is essential to find new approaches to stimulate β-cell…”
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