Search Results - "Zummo, Francesco P"

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    Glucagon-Like Peptide 1 Protects Pancreatic β-Cells From Death by Increasing Autophagic Flux and Restoring Lysosomal Function by Zummo, Francesco P, Cullen, Kirsty S, Honkanen-Scott, Minna, Shaw, James A M, Lovat, Penny E, Arden, Catherine

    Published in Diabetes (New York, N.Y.) (01-05-2017)
    “…Studies in animal models of type 2 diabetes have shown that glucagon-like peptide 1 (GLP-1) receptor agonists prevent β-cell loss. Whether GLP-1 mediates…”
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    Journal Article
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    Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis by Zummo, Francesco P, Krishnanda, Stanislaus I, Georgiou, Merilin, O'Harte, Finbarr PM, Parthsarathy, Vadivel, Cullen, Kirsty S, Honkanen-Scott, Minna, Shaw, James AM, Lovat, Penny E, Arden, Catherine

    Published in Autophagy (03-04-2022)
    “…Macroautophagy/autophagy is critical for the regulation of pancreatic β-cell mass and its deregulation has been implicated in the pathogenesis of type 2…”
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    Journal Article
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    Differential effects of saturated and unsaturated fatty acids on autophagy in pancreatic β-cells by Dhayal, Shalinee, Zummo, Francesco P, Anderson, Matthew W, Thomas, Patricia, Welters, Hannah J, Arden, Catherine, Morgan, Noel G

    Published in Journal of molecular endocrinology (01-11-2019)
    “…Long-chain saturated fatty acids are lipotoxic to pancreatic β-cells, whereas most unsaturates are better tolerated and some may even be cytoprotective. Fatty…”
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    Journal Article
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    Heterozygous inactivation of plasma membrane Ca(2+)-ATPase in mice increases glucose-induced insulin release and beta cell proliferation, mass and viability by Pachera, Nathalie, Papin, Julien, Zummo, Francesco P, Rahier, Jacques, Mast, Jan, Meyerovich, Kira, Cardozo, Alessandra K, Herchuelz, André

    Published in Diabetologia (01-12-2015)
    “…Calcium plays an important role in the process of glucose-induced insulin release in pancreatic beta cells. These cells are equipped with a double system…”
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    Journal Article
  7. 7

    Heterozygous inactivation of plasma membrane Ca2+-ATPase in mice increases glucose-induced insulin release and beta cell proliferation, mass and viability by Pachera, Nathalie, Papin, Julien, Zummo, Francesco P., Rahier, Jacques, Mast, Jan, Meyerovich, Kira, Cardozo, Alessandra K., Herchuelz, André

    Published in Diabetologia (01-12-2015)
    “…Aims/hypothesis Calcium plays an important role in the process of glucose-induced insulin release in pancreatic beta cells. These cells are equipped with a…”
    Get full text
    Journal Article
  8. 8

    Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca 2+ -PPP3/calcineurin-TFEB axis by Zummo, Francesco P, Krishnanda, Stanislaus I, Georgiou, Merilin, O'Harte, Finbarr Pm, Parthsarathy, Vadivel, Cullen, Kirsty S, Honkanen-Scott, Minna, Shaw, James Am, Lovat, Penny E, Arden, Catherine

    Published in Autophagy (03-04-2022)
    “…Macroautophagy/autophagy is critical for the regulation of pancreatic β-cell mass and its deregulation has been implicated in the pathogenesis of type 2…”
    Get full text
    Journal Article
  9. 9

    Heterozygous inactivation of plasma membrane Ca^sup 2+^-ATPase in mice increases glucose-induced insulin release and beta cell proliferation, mass and viability by Pachera, Nathalie, Papin, Julien, Zummo, Francesco P, Rahier, Jacques, Mast, Jan, Meyerovich, Kira, Cardozo, Alessandra K, Herchuelz, André

    Published in Diabetologia (01-12-2015)
    “…Aims/hypothesis Calcium plays an important role in the process of glucose-induced insulin release in pancreatic beta cells. These cells are equipped with a…”
    Get full text
    Journal Article