Search Results - "Zumbrunn, Jürg"

Taurolidine Acts on Bacterial Virulence Factors and Does Not Induce Resistance in Periodontitis-Associated Bacteria-An In-Vitro Study by Radakovic, Sabrina, Andreoli, Nicola, Schmid, Simon, Nietzsche, Sandor, Zumbrunn, Jürg, Sculean, Anton, Eick, Sigrun

“…The aims of the present study were: (a) to determine the mechanism of action of taurolidine against bacterial species associated with periodontal disease, and…”
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Primary structure of a putative serine protease specific for IGF-binding proteins by Zumbrunn, Jürg, Trueb, Beat

“…From a subtracted cDNA library we have isolated a cDNA clone coding for a novel transformation-sensitive protein which is expressed by human fibroblasts, but…”
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Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa by Srinivas, Nityakalyani, Jetter, Peter, Ueberbacher, Bernhard J, Werneburg, Martina, Zerbe, Katja, Steinmann, Jessica, Van der Meijden, Benjamin, Bernardini, Francesca, Lederer, Alexander, Dias, Ricardo L.A, Misson, Pauline E, Henze, Heiko, Zumbrunn, Jürg, Gombert, Frank O, Obrecht, Daniel, Hunziker, Peter, Schauer, Stefan, Ziegler, Urs, Käch, Andres, Eberl, Leo, Riedel, Kathrin, DeMarco, Steven J, Robinson, John A

“…Antibiotics with new mechanisms of action are urgently required to combat the growing health threat posed by resistant pathogenic microorganisms. We…”
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Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability by Kroboth, Karin, Newton, Ian P, Kita, Katsuhiro, Dikovskaya, Dina, Zumbrunn, Jürg, Waterman-Storer, Clare M, Näthke, Inke S

“…Most sporadic colorectal tumors carry truncation mutations in the adenomatous polyposis coli (APC) gene. The APC protein is involved in many processes that…”
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Discovery of Highly Potent and Selective CXCR4 Inhibitors Using Protein Epitope Mimetics (PEM) Technology by Alexander Lederer, John A. Robinson, Kerstin Moehle, Thomas Klimkait, François Hamy, Vincent Brondani, Sergio Lociuro, Jean-Pierre Obrecht, Jan Willem Vrijbloed, Christian Ludin, Frank O. Gombert, Federico Brianza, Jürg Zumbrunn, Reshmi Mukherjee, Barbara Romagnoli, Heiko Henze, Steven J. DeMarco, Daniel Obrecht

“…Novel, highly potent CXCR4 inhibitors with good pharmacokinetic properties were obtained by applying PEM technology starting from the naturally occurring…”
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Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3β phosphorylation by Zumbrunn, Jürg, Kinoshita, Kazuhisa, Hyman, Anthony A., Näthke, Inke S.

“…Truncation mutations in the adenomatous polyposis coli protein (APC) are responsible for familial polyposis, a form of inherited colon cancer. In addition to…”
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In vitro activity of taurolidine gel on bacteria associated with periodontitis by Eick, Sigrun, Gloor, Nicoletta, Püls, Cecilia, Zumbrunn, Jürg, Sculean, Anton

“…Objectives The purpose of this in vitro study was to determine the antimicrobial activity of two different taurolidine gel formulations in comparison with…”
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Discovery of novel, highly potent and selective β-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles by DeMarco, Steven J., Henze, Heiko, Lederer, Alexander, Moehle, Kerstin, Mukherjee, Reshmi, Romagnoli, Barbara, Robinson, John A., Brianza, Federico, Gombert, Frank O., Lociuro, Sergio, Ludin, Christian, Vrijbloed, Jan Willem, Zumbrunn, Jürg, Obrecht, Jean-Pierre, Obrecht, Daniel, Brondani, Vincent, Hamy, François, Klimkait, Thomas

“…Protein epitope mimetics (PEM) of Polyphemusin II act as highly potent CXCR4 inhibitors with good in vivo pharmacokinetic properties. Novel highly potent CXCR4…”
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An α-Actinin Binding Site of Zyxin Is Essential for Subcellular Zyxin Localization and α-Actinin Recruitment by Reinhard, Matthias, Zumbrunn, Jürg, Jaquemar, Daniel, Kuhn, Monika, Walter, Ulrich, Trueb, Beat

“…The LIM domain protein zyxin is a component of adherens type junctions, stress fibers, and highly dynamic membrane areas and appears to be involved in…”
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The adenomatous polyposis coli protein: in the limelight out at the edge by Dikovskaya, Dina, Zumbrunn, Jürg, Penman, George A, Näthke, Inke S

“…Truncation mutations in the adenomatous polyposis coli protein (APC) are responsible for familial and sporadic colonic tumours. APC is best known for its role…”
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Localization of the Gene for a Serine Protease with IGF-Binding Domain (PRSS11) to Human Chromosome 10q25.3–q26.2 by Zumbrunn, Jürg, Trueb, Beat

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Influenza Hemagglutinin-Mediated Membrane Fusion: Influence of Receptor Binding on the Lag Phase Preceding Fusion by Stegmann, Toon, Bartoldus, Ingrid, Zumbrunn, Juerg

“…Fusion of influenza virus with liposomes is triggered by low pH, resulting in a conformational change in the fusion protein (HA) and the insertion of fusion…”
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A Zyxin‐Related Protein whose Synthesis is Reduced in Virally Transformed Fibroblasts by Zumbrunn, Jürg, Trueb, Beat

“…We have cloned the gene for a novel LIM‐domain protein from human fibroblasts whose expression is substantially decreased in simian‐virus‐40‐(SV40)‐transformed…”
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