Search Results - "Zumbrägel, Nadine"
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Vanadium-Catalyzed Dehydrogenation of N‑Heterocycles in Water
Published in Organic letters (17-08-2018)“…In this paper, the dehydrogenation of tetrahydroquinolines using oxovanadium(V) catalysts under mild conditions in water and oxygen atmosphere is described…”
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2
Chiral Dinuclear Vanadium Complex-Mediated Oxidative Coupling of Resorcinols
Published in Journal of organic chemistry (01-02-2019)“…A method for the highly regio- and enantioselective oxidative coupling of resorcinols has been established by using dibrominated dinuclear vanadium(V)…”
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Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis
Published in Nature communications (16-05-2018)“…The 3-thiazolidine ring represents an important structural motif in life sciences molecules. However, up to now reduction of 3-thiazolines as an attractive…”
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Merging Heterocyclic Chemistry and Biocatalysis in One-Pot Processes through Compartmentalization of the Reaction Steps
Published in Bioengineering (Basel) (01-08-2018)“…A proof of concept for a one-pot process merging a heterocycle formation by a classical chemical approach at basic conditions with a biocatalytic reduction,…”
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Structural Characterization of an S -enantioselective Imine Reductase from Mycobacterium Smegmatis
Published in Biomolecules (Basel, Switzerland) (31-07-2020)“…NADPH-dependent imine reductases (IREDs) are enzymes capable of enantioselectively reducing imines to chiral secondary amines, which represent important…”
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One-pot synthesis of a 3-thiazolidine through combination of an Asinger-type multi-component-condensation reaction with an enzymatic imine reduction
Published in Journal of biotechnology (10-02-2019)“…•Combination of heterocyclic chemistry and biocatalysis within a one-pot synthesis was achieved for a 3-thiazolidine synthesis.•Asinger-type…”
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Lipase-Catalyzed Chemoselective Ester Hydrolysis of Biomimetically Coupled Aryls for the Synthesis of Unsymmetric Biphenyl Esters
Published in Molecules (Basel, Switzerland) (23-11-2019)“…Lipases are among the most frequently used biocatalysts in organic synthesis, allowing numerous environmentally friendly and inexpensive chemical…”
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Enantioselective Biocatalytic Reduction of 2H‑1,4-Benzoxazines Using Imine Reductases
Published in Journal of organic chemistry (01-02-2019)“…A biocatalytic reduction of 2H-1,4-benzoxazines using imine reductases is reported. This process enables a smooth and enantioselective synthesis of the…”
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Enantioselective Biocatalytic Reduction of 2 H-1,4-Benzoxazines Using Imine Reductases
Published in Journal of organic chemistry (01-02-2019)“…A biocatalytic reduction of 2 H-1,4-benzoxazines using imine reductases is reported. This process enables a smooth and enantioselective synthesis of the…”
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10
Biocatalytic Reduction of 2‐Monosubstituted 3‐Thiazolines Using Imine Reductases
Published in Journal of heterocyclic chemistry (01-03-2019)“…The application of a straightforward biocatalytic technology for the reduction of racemic 2‐monosubstituted 3‐thiazolines, which are easily prepared via…”
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Asymmetric Biocatalytic Reduction of Cyclic Imines: Design and Application of a Tailor-Made Whole-Cell Catalyst
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Expanding the Scope of Asinger Chemistry towards Enantiomerically Pure Secondary Amines and β-Aminothiols through Chemoenzymatic Derivatization of 3-Thiazolines
Published in Chemistry an international journal (01-12-2019)“…A proof of concept for a novel approach towards enantiomerically highly enriched acyclic secondary amines and β-aminothiols as non-cyclic target molecules when…”
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