Persistence of serum antibodies of Sarcocystis neurona in horses moved from North America to India

The study reported here was undertaken to assess the presence of antibodies to Sarcocystis neurona in the serum of horses of North American origin that had been relocated for 1 year or more to India (ie, outside of the known endemic areas for S. neurona). The presence or absence of such antibodies s...

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Bibliographic Details
Published in:	Journal of veterinary internal medicine Vol. 20; no. 4; pp. 994 - 997
Main Authors:	Brown, C.M, Morrow, J.K, Carleton, C.L, Ramanathan, B, Reddy, R, Vaidya, V, Karthikeyan, S.M, Zulfikar, A.A, Kannadkar, V.S
Format:	Journal Article
Language:	English
Published:	United States 01-07-2006
Subjects:	Animals Antibodies, Protozoan - blood chronic diseases disease course equine protozoal myeloencephalitis Europe - epidemiology Horse Diseases - epidemiology Horses immunology India - epidemiology North America - epidemiology Sarcocystis - immunology Sarcocystis neurona Sarcocystosis - epidemiology Sarcocystosis - veterinary seroprevalence Time Factors Transportation North America Europe India
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Summary:	The study reported here was undertaken to assess the presence of antibodies to Sarcocystis neurona in the serum of horses of North American origin that had been relocated for 1 year or more to India (ie, outside of the known endemic areas for S. neurona). The presence or absence of such antibodies should provide information concerning the persistence of such antibodies, or support the presence of chronic infection, or both. A total of 228 Thoroughbred horses were sampled in India, of which 86 were of North American origin that had been in India between 1 and 13 years, 124 were Indian-born horses that had never been out of India, 8 were of Irish origin, 8 were of English origin, and 2 were originally from France. Sera were tested using established western blot analysis. Of the Indian-born horses, 0.8% were test positive, and of the North American horses, 42% were test positive. All of the English and Irish horses were test negative, and the 2 French horses were test positive. These data indicate that antibodies against S. neurona can be detected for many years after horses have been removed from an endemic area and that this may be attributable to long half-life of the antibodies or to chronic infection and ongoing antibody production, or both.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0891-6640 1939-1676
DOI:	10.1892/0891-6640(2006)20[994:POSATS]2.0.CO;2