Search Results - "Zukiwski, A"

Trans-ungual Delivery of AR-12, a Novel Antifungal Drug by Kushwaha, Avadhesh Singh, Sharma, P., Shivakumar, H. N., Rappleye, C., Zukiwski, A., Proniuk, S., Murthy, S. Narasimha

“…AR-12 is a novel small molecule with broad spectrum antifungal activity. Recently, AR-12 was found to be highly active against Trichophyton rubrum , one of the…”
Get full text

473 Evaluation of the Relation Specific PR Biomarkers to the Preclinical Activity of Onapristone by Serin, G, Gilles, E, Zukiwski, A

Get full text

Phase 1-2 study of progesterone receptor (PR) inhibition with extended-release (ER) onapristone (ONA) alone or in combination with abiraterone (AA) in patients (pts) with castration-resistant prostate cancer (CRPC) incorporating plasma DNA analysis to define androgen receptor (AR) status by Jayaram, A., Nowakowska, K., Mateo, J., Hernandez, T., Kumar, S., Fulton, B., Nava Rodrigues, D., Riisnaes, R., Zukiwski, A., Proniuk, S., Bexon, A.S., Bisaha, J., Bianchini, D., Zafeiriou, Z., Lopez, R.P., Tunariu, N., Pacey, S., Jones, R., de Bono, J. Sebastian, Attard, G.

Get full text

431 Real-time pharmacokinetic (PK) results from an ongoing randomized, parallel-dose phase 1 study of onapristone in patients (pts) with progesterone receptor (PR)-expressing cancers by Lokiec, F, Bonneterre, J, Italiano, A, Varga, A, Campone, M, LeSimple, T, Leary, A, Dieras, V, Rezai, K, Giacchetti, S, Proniuk, S, Bexon, A, Gilles, E, Bisaha, J, Zukiwski, A, Cottu, P

Get full text

Phase II study of ketoconazole combined with weekly doxorubicin in patients with androgen-independent prostate cancer by Sella, A, Kilbourn, R, Amato, R, Bui, C, Zukiwski, A A, Ellerhorst, J, Logothetis, C J

“…A phase II clinical trial was performed to assess the antitumor activity and toxicity of ketoconazole in combination with doxorubicin (Adriamycin; Adria…”
Get more information

Escalated MVAC with or without recombinant human granulocyte-macrophage colony-stimulating factor for the initial treatment of advanced malignant urothelial tumors: results of a randomized trial by Logothetis, C J, Finn, L D, Smith, T, Kilbourn, R G, Ellerhorst, J A, Zukiwski, A A, Sella, A, Tu, S M, Amato, R J

“…Hematopoietic growth factors have been shown to ameliorate the side effects of chemotherapy. Here we assess the ability of recombinant human…”
Get more information

Phase I trial of murine monoclonal antibody 14G2a administered by prolonged intravenous infusion in patients with neuroectodermal tumors by Murray, J L, Cunningham, J E, Brewer, H, Mujoo, K, Zukiwski, A A, Podoloff, D A, Kasi, L P, Bhadkamkar, V, Fritsche, H A, Benjamin, R S

“…The purpose of this phase I trial was to determine the toxicity and maximum-tolerated dose (MTD) of murine monoclonal antibody (Mab) 14G2a (anti-GD2) in cancer…”
Get more information

Development of a technique to detect the activated form of the progesterone receptor and correlation with clinical and histopathological characteristics of endometrioid adenocarcinoma of the uterine corpus by Bonneterre, Jacques, Hutt, Emilie, Bosq, Jacques, Graham, J. Dinny, Powell, Matthew A, Leblanc, Eric, Fujiwara, Keiichi, Herzog, Thomas J, Coleman, Robert L, Clarke, Christine L, Gilles, Erard M, Zukiwski, Alexander A, Monk, Bradley J

“…Abstract Objective Hormonal therapy is generally reserved for patients with endometrial cancers that fail cytotoxic chemotherapy, but there is a lack of…”
Get full text

Phase II trial of low dose gamma-interferon in metastatic renal cell carcinoma by Ellerhorst, J A, Kilbourn, R G, Amato, R J, Zukiwski, A A, Jones, E, Logothetis, C J

“…We conducted a phase II trial to confirm the activity of fixed, low dose gamma-interferon in metastatic renal cell carcinoma. A total of 35 patients with…”
Get more information

Tumour and cellular distribution of activated forms of PR in breast cancers: a novel immunohistochemical analysis of a large clinical cohort by Bonneterre, Jacques, Bosq, Jacques, Jamme, Philippe, Valent, Alexander, Gilles, Erard M, Zukiwski, Alexander A, Fuqua, Suzanne A W, Lange, Carol A, O'Shaughnessy, Joyce

“…BackgroundThe progesterone receptor (PR) is expressed by ∼70% of early breast tumours and is implicated in the progression of breast cancer. In cancerous…”
Get full text

Abstract P6-05-13: Tumor and cellular distribution of activated forms of ER and PR in breast cancers by Bonneterre, J, Bosq, J, Valent, A, Gilles, E, Zukiwski, A

“…Abstract Background: Hormonal therapy is considered one of the most effective treatment options for patients with estrogen receptor (ER) and/or progesterone…”
Get full text

Increased incidence of hypersensitivity to iodine-containing radiographic contrast media after interleukin-2 administration by Zukiwski, A A, David, C L, Coan, J, Wallace, S, Gutterman, J U, Mavligit, G M

“…Eight of 28 (28%) cancer patients with liver metastases treated by either splenic (four) or hepatic (four) arterial infusion of recombinant interleukin-2…”
Get more information

Combination recombinant interleukin-2, recombinant interferon-alpha, and 5-fluorouracil for treatment of metastatic renal cell carcinoma by Ueno, N T, Zukiwski, A A

Get more information

Splenic versus hepatic artery infusion of interleukin-2 in patients with liver metastases by Mavligit, G M, Zukiwski, A A, Gutterman, J U, Salem, P, Charnsangavej, C, Wallace, S

“…In an attempt to improve the therapeutic index of recombinant interleukin-2 (rIL-2) by generating or activating lymphokine-activated killer (LAK) cells and…”
Get more information

Regression of hepatic metastases from gastrointestinal leiomyosarcoma after hepatic arterial chemoembolization by Mavligit, G M, Zukiwski, A A, Salem, P A, Lamki, L, Wallace, S

“…Two patients with gastrointestinal leiomyosarcoma metastatic to the liver were treated by hepatic chemoembolization with cisplatin and polyvinyl sponge…”
Get more information

Indium-111-Labeled B72.3 Monoclonal Antibody in the Detection and Staging of Breast Cancer: A Phase I Study by Lamki, Lamk M, Buzdar, Aman U, Singletary, S. Eva, Rosenblum, Michael G, Bhadkamkar, Vijaya, Esparza, Laura, Podoloff, Donald A, Zukiwski, Alexander, Hortobagyi, Gabriel N, Murray, James L

“…Sixteen patients with primary breast cancer were studied with a pancarcinoma monoclonal antibody B72.3, an IgG1 molecule directed against tumor-associated…”
Get full text

Regional biologic therapy. Hepatic arterial infusion of recombinant human tumor necrosis factor in patients with liver metastases by Mavligit, G M, Zukiwski, A A, Charnsangavej, C, Carrasco, C H, Wallace, S, Gutterman, J U

“…Twenty-two chemotherapy-resistant patients with liver metastases received 46 courses of recombinant human tumor necrosis factor (rhTNF) administered by 5-day…”
Get more information

Alteration in interactions between tumor-infiltrating lymphocytes and tumor cells in human melanomas after chemotherapy or immunotherapy by ITOH, K, HAYAKAWA, K, RING, S. E, LAPUSHIN, R, AUGUSTUS, L. B, SALMERON, M. A, LEGHA, S. S, MURRAY, J. L, TALPAZ, M, BALCH, C. M, PARKINSON, D. R, LEE, K, ZUKIWSKI, A. A

“…Alteration in interactions between tumor-infiltrating lymphocytes (TILs) and tumor cells after chemotherapy or immunotherapy was studied in metastatic melanoma…”
Get full text

Severe, symptomatic, dose-limiting hypophosphatemia induced by hepatic arterial infusion of recombinant tumor necrosis factor in patients with liver metastases by del Giglio, A, Zukiwski, A A, Ali, M K, Mavligit, G M

“…Twenty-two patients with liver metastases received 45 courses of recombinant tumor necrosis factor (rTNF) by hepatic arterial infusion in doses ranging from…”
Get more information

5-Fluorouracil and interferon-alpha in chemotherapy refractory bladder carcinoma: an effective regimen by Logothetis, C J, Hossan, E, Recondo, G, Sella, A, Ellerhorst, J, Kilbourn, R, Zukiwski, A, Amato, R

“…Seventy-seven patients with metastatic transitional cell carcinoma of the bladder who were unable to receive primary Cisplatin-based therapy or failed primary…”
Get more information