Search Results - "Zukić, Branka"
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Germline Variants in Cancer Predisposition Genes in Pediatric Patients with Central Nervous System Tumors
Published in International journal of molecular sciences (12-12-2023)“…Central nervous system (CNS) tumors comprise around 20% of childhood malignancies. Germline variants in cancer predisposition genes (CPGs) are found in…”
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The pharmacogenomics of vincristine-induced peripheral neuropathy in pediatric acute lymphoblastic leukemia patients in Serbia - a single center experience
Published in Srpski arhiv za celokupno lekarstvo (2022)“…Introduction/Objective. Vincristine (VCR) is one of the key drugs in current treatment protocols for pediatric acute lymphoblastic leukemia (ALL). By…”
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Genetic basis of otosclerosis
Published in Srpski arhiv za celokupno lekarstvo (01-09-2020)“…Introduction. Otosclerosis is a disorder of the bone labyrinth and stapes resulting in conductive hearing loss. The genetic basis of otosclerosis still remains…”
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Pharmacogenomics landscape of COVID-19 therapy response in Serbian population and comparison with worldwide populations
Published in Journal of medical biochemistry (01-01-2020)“…Since there are no certified therapeutics to treat COVID-19 patients, drug repurposing became important. With lack of time to test individual pharmacogenomics…”
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Genetic predictors of celiac disease, lactose intolerance, and vitamin D function and presence of peptide morphins in urine of children with neurodevelopmental disorders
Published in Nutritional neuroscience (02-01-2019)“…Gastrointestinal disturbances, nutritional deficiencies, and food intolerances are frequently observed in children with neurodevelopmental disorders (NDD). To…”
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Expression pattern of long non-coding RNA growth arrest-specific 5 in the remission induction therapy in childhood acute lymphoblastic leukemia
Published in Journal of medical biochemistry (01-07-2019)“…Long non-coding RNA growth arrest-specific 5 ( ) is deregulated in many cancers because of its role in cell growth arrest and apoptosis. Additionally,…”
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Variants in TPMT, ITPA, ABCC4 And ABCB1 Genes as Predictors of 6-Mercaptopurine Induced Toxicity in Children with Acute Lymphoblastic Leukemia
Published in Journal of medical biochemistry (01-07-2018)“…Acute lymphoblastic leukemia is the most common childhood malignancy. Optimal use of anti leukemic drugs has led to less toxicity and adverse reactions, and a…”
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HLA genotyping in pediatric celiac disease patients
Published in Biomolecules & biomedicine (01-08-2014)“…Celiac disease (CD) is a chronic inflammatory disease in the small intestine triggered by gluten uptake that occurs in genetically susceptible individuals…”
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PERSONALIZATION OF 6-MERCAPTOPURINE THERAPY FOR CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Published in Archives of disease in childhood (01-01-2016)“…IntroductionTreatment of acute lymphoblastic leukemia (ALL) in children has been significantly improved over past few decades. Optimal use of known…”
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Molecular genetic markers as a basis for personalized medicine
Published in Journal of medical biochemistry (01-01-2014)“…Nowadays, genetics and genomics are fully integrated into medical practice. Personalized medicine, also called genome-based medicine, uses the knowledge of the…”
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Significance of UGT1A128 Genotype in Patients with Advanced Liver Injury Caused by Chronic Hepatitis C
Published in Journal of medical biochemistry (01-03-2019)“…Chronic hepatitis C (CHC) is a significant cause of liver related morbidity and mortality worldwide. The role of genetics in the host response to hepatitis C…”
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Importance of pharmacogenetic markers in the methylenetetrahydrofolate reductase gene during methotrexate treatment in pediatric patients with acute lymphoblastic leukemia
Published in Archives of biological sciences (2017)“…Despite remarkable progress in survival of children with acute lymphoblastic leukemia (ALL) which has reached about 85%, early toxicity and relapse rate remain…”
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Molecular Genetic Markers as a Basis for Personalized Medicine / MOLEKULARNO-GENETIČKI MARKERI KAO OSNOV ZA PERSONALIZOVANU MEDICINU
Published in Journal of medical biochemistry (01-01-2014)“…Nowadays, genetics and genomics are fully integrated into medical practice. Personalized medicine, also called genome-based medicine, uses the knowledge of the…”
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Individualized Therapy: Role of Thiopurine S-Methyltransferase Protein and Genetic Variants
Published in Journal of medical biochemistry (01-07-2010)“…Thiopurine S-methyltransferase (TPMT: EC 2.1.1.67) is an enzyme that metabolizes immunosuppressive thiopurine medications, used in the treatment of autoimmune…”
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The first insight into the genetic structure of the population of modern Serbia
Published in Scientific reports (07-07-2021)“…The complete understanding of the genomic contribution to complex traits, diseases, and response to treatments, as well as genomic medicine application to the…”
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Can Pharmacogenetic Variants in TPMT , MTHFR and SLCO1B1 Genes Be Used as Potential Markers of Outcome Prediction in Systemic Sclerosis Patients?
Published in International journal of molecular sciences (10-05-2023)“…Systemic sclerosis (SSc) is a rare connective tissue disorder with highest morbidity and mortality among rheumatologic diseases. Disease progression is highly…”
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Clinical Application of Thiopurine Pharmacogenomics in Pediatrics
Published in Current drug metabolism (01-01-2020)“…Thiopurine drugs are used for the treatment of pediatric diseases. Inter-individual differences in the metabolism of these drugs greatly influence the risk of…”
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Diagnostic and Therapeutic Implications of Long Non-Coding RNAs in Leukemia
Published in Life (Basel, Switzerland) (01-11-2022)“…Leukemia is a heterogenous group of hematological malignancies categorized in four main types (acute myeloid leukemia (AML), acute lymphoblastic leukemia…”
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The long non-coding RNA GAS5 contributes to the suppression of inflammatory responses by inhibiting NF-κB activity
Published in Frontiers in pharmacology (09-10-2024)“…Nuclear factor kappa B (NF-κB) is a key regulator of immune and inflammatory responses. Glucocorticoid drugs (GC) act through the glucocorticoid receptor (GR)…”
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The role of FasR/FasL system in pathogenesis of myeloprolyferative neoplasms
Published in Archives of biological sciences (2010)“…Myeloproliferative neoplasms (MPN) are hematological malignancies characterized by uncontrolled cell proliferation and impaired apoptosis. The FasR/FasL system…”
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