Search Results - "Zuker, C. S."

A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade by Zuker, Charles S, Tsunoda, Susan, Sierralta, Jimena, Sun, Yumei, Bodner, Ruth, Suzuki, Emiko, Becker, Ann, Socolich, Michael

“…How are signalling molecules organized into different pathways within the same cell? In Drosophila, the inaD gene encodes a protein consisting of five PDZ…”
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Assembly of the Drosophila phototransduction cascade into a signalling complex shapes elementary responses by Zuker, Charles S, Scott, Kristin

“…The subcellular compartmentalization of signalling molecules helps to ensure the selective activation of different signal-transduction cascades within a single…”
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The organization of INAD-signaling complexes by a multivalent PDZ domain protein in Drosophila photoreceptor cells ensures sensitivity and speed of signaling by Tsunoda, S., Zuker, C.S.

“…Phototransduction in Drosophila has emerged as an attractive model system for studying the organization of signaling cascades in vivo. In photoreceptor…”
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The biology of vision in Drosophila by Zuker, C.S. (University of California at San Diego, La Jolla, CA.)

“…Phototransduction systems in vertebrates and invertebrates share a great deal of similarity in overall strategy but differ significantly in the underlying…”
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The receptors and coding logic for bitter taste by Mueller, K. L, Hoon, M. A, Erlenbach, I, Chandrashekar, J, Zuker, C. S, Ryba, N. J. P

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Defective Intracellular Transport is the Molecular Basis of Rhodopsin- Dependent Dominant Retinal Degeneration by Colley, Nansi J., Cassill, J. Aaron, Baker, Elizabeth K., Zuker, Charles S.

“…Retinitis pigmentosa (RP) is a group of hereditary human diseases that cause retinal degeneration and lead to eventual blindness. More than 25% of all RP cases…”
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Signal transduction in Drosophila photoreceptors by RAMA RANGANATHAN, MALICKI, D. M, ZUKER, C. S

“…The ability to sense and to react to environmental stimuli is crucial for the survival of any organism. The primary event in sensory information processing is…”
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Ectopic expression of ultraviolet-rhodopsins in the blue photoreceptor cells of Drosophila: visual physiology and photochemistry of transgenic animals by Feiler, R, Bjornson, R, Kirschfeld, K, Mismer, D, Rubin, GM, Smith, DP, Socolich, M, Zuker, CS

“…We have generated transgenic flies expressing R7 cell-specific opsins in the major class of photoreceptor cells of the Drosophila retina and characterized…”
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Neurobiology of eating behavior, nutrition and health by Stover, P J, Field, M S, Andermann, M L, Bailey, R L, Batterham, R L, Cauffman, E, Frühbeck, G, Iversen, P O, Starke-Reed, P, Sternson, S M, Vinoy, S, Witte, A V, Zuker, C S, Angelin, B

“…Eating behavior and food-related decision making are among the most complex of the motivated behaviors, and understanding the neurobiology of eating behavior,…”
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Arrestin Function in Inactivation of G Protein-Coupled Receptor Rhodopsin in Vivo by Dolph, Patrick J., Ranganathan, Rama, Colley, Nansi J., Hardy, Robert W., Socolich, Michael, Zuker, Charles S.

“…Arrestins have been implicated in the regulation of many G protein-coupled receptor signaling cascades. Mutations in two Drosophila photoreceptor-specific…”
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An amino-acid taste receptor by Zuker, Charles S, Nelson, Greg, Chandrashekar, Jayaram, Hoon, Mark A, Feng, Luxin, Zhao, Grace, Ryba, Nicholas J. P

“…The sense of taste provides animals with valuable information about the nature and quality of food. Mammals can recognize and respond to a diverse repertoire…”
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Coding of Sweet, Bitter, and Umami Tastes: Different Receptor Cells Sharing Similar Signaling Pathways by Zhang, Yifeng, Hoon, Mark A., Chandrashekar, Jayaram, Mueller, Ken L., Cook, Boaz, Wu, Dianqing, Zuker, Charles S., Ryba, Nicholas J.P.

“…Mammals can taste a wide repertoire of chemosensory stimuli. Two unrelated families of receptors (T1Rs and T2Rs) mediate responses to sweet, amino acids, and…”
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Decoding Cilia Function: Defining Specialized Genes Required for Compartmentalized Cilia Biogenesis by Avidor-Reiss, Tomer, Maer, Andreia M, Koundakjian, Edmund, Polyanovsky, Andrey, Keil, Thomas, Subramaniam, Shankar, Zuker, Charles S

“…The evolution of the ancestral eukaryotic flagellum is an example of a cellular organelle that became dispensable in some modern eukaryotes while remaining an…”
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The cyclophilin homolog ninaA is required in the secretory pathway by Colley, N J, Baker, E K, Stamnes, M A, Zuker, C S

“…In Drosophila, the major rhodopsin Rh1 is synthesized in endoplasmic reticulum (ER)-bound ribosomes of the R1-R6 photoreceptor cells and is then transported to…”
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Mammalian Sweet Taste Receptors by Nelson, Greg, Hoon, Mark A., Chandrashekar, Jayaram, Zhang, Yifeng, Ryba, Nicholas J.P., Zuker, Charles S.

“…The sense of taste provides animals with valuable information about the quality and nutritional value of food. Previously, we identified a large family of…”
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A G Protein-Coupled Receptor Phosphatase Required for Rhodopsin Function by Vinós, Javier, Jalink, Kees, Hardy, Robert W., Britt, Steven G., Zuker, Charles S.

“…Heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors are phosphorylated by kinases that mediate agonist-dependent receptor…”
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On the Evolution of Eyes: Would You Like It Simple or Compound? by Zuker, Charles S.

“…A homolog of the Pax-6 gene, which regulates eye development in vertebrates, has been found in Drosophila, contradicting prevailing theory that the eyes of…”
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A Drosophila Mechanosensory Transduction Channel by Walker, Richard G., Willingham, Aarron T., Zuker, Charles S.

“…Mechanosensory transduction underlies a wide range of senses, including proprioception, touch, balance, and hearing. The pivotal element of these senses is a…”
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T2Rs Function as Bitter Taste Receptors by Chandrashekar, Jayaram, Mueller, Ken L, Hoon, Mark A, Adler, Elliot, Feng, Luxin, Guo, Wei, Zuker, Charles S, Ryba, Nicholas J.P

“…Bitter taste perception provides animals with critical protection against ingestion of poisonous compounds. In the accompanying paper, we report the…”
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A Novel Family of Mammalian Taste Receptors by Adler, Elliot, Hoon, Mark A, Mueller, Ken L, Chandrashekar, Jayaram, Ryba, Nicholas J.P, Zuker, Charles S

“…In mammals, taste perception is a major mode of sensory input. We have identified a novel family of 40–80 human and rodent G protein–coupled receptors…”
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