Search Results - "Zuk, O."
-
1
Polygenic embryo screening: four clinical considerations warrant further attention
Published in Human reproduction (Oxford) (30-06-2022)“…ABSTRACT Recent advances in developing polygenic scores have made it possible to screen embryos for common, complex conditions and traits. Polygenic embryo…”
Get full text
Journal Article -
2
Sorting points into neighborhoods (SPIN): data analysis and visualization by ordering distance matrices
Published in Bioinformatics (15-05-2005)“…We introduce a novel unsupervised approach for the organization and visualization of multidimensional data. At the heart of the method is a presentation of the…”
Get full text
Journal Article -
3
From Finite-System Entropy to Entropy Rate for a Hidden Markov Process
Published in IEEE signal processing letters (01-09-2006)“…A recent result presented the expansion for the entropy rate of a hidden Markov process (HMP) as a power series in the noise variable epsi. The coefficients of…”
Get full text
Journal Article -
4
O-056 Evaluating the utility of screening human IVF embryos with polygenic risk scores for complex diseases
Published in Human reproduction (Oxford) (06-08-2021)“…Abstract Study question It is now feasible to screen human IVF embryos with “polygenic risk scores” for predicting complex disease risk. What is the expected…”
Get full text
Journal Article -
5
Thousands of Samples Are Needed to Generate a Robust Gene List for Predicting Outcome in Cancer
Published in Proceedings of the National Academy of Sciences - PNAS (11-04-2006)“…Predicting at the time of discovery the prognosis and metastatic potential of cancer is a major challenge in current clinical research. Numerous recent studies…”
Get full text
Journal Article -
6
Bacterial community reconstruction using compressed sensing
Published in Journal of computational biology (01-11-2011)“…Bacteria are the unseen majority on our planet, with millions of species and comprising most of the living protoplasm. We propose a novel approach for…”
Get more information
Journal Article -
7
Identification of rare alleles and their carriers using compressed se(que)nsing
Published in Nucleic acids research (01-10-2010)“…Identification of rare variants by resequencing is important both for detecting novel variations and for screening individuals for known disease alleles. New…”
Get full text
Journal Article -
8
FDR CONTROL WITH ADAPTIVE PROCEDURES AND FDR MONOTONICITY
Published in The annals of applied statistics (01-06-2011)“…The steep rise in availability and usage of high-throughput technologies in biology brought with it a clear need for methods to control the False Discovery…”
Get full text
Journal Article -
9
Identification of rare alleles and their carriers using compressed se(que)nsing
Published in Nucleic acids research (01-03-2011)Get full text
Journal Article -
10
The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation
Published in Molecular systems biology (2005)“…Deciphering regulatory events that drive malignant transformation represents a major challenge for systems biology. Here, we analyzed genome‐wide transcription…”
Get full text
Journal Article -
11
Applications of the Montgomery exponent
Published in International Conference on Information Technology: Coding and Computing (ITCC'05) - Volume II (2005)“…We define here the Montgomery exponent of order s, modulo the odd integer N, by MEXP = MEXP(A,X,N,s) = A/sup X/2/sup -s(X-1)/ (mod N), and illustrate some…”
Get full text
Conference Proceeding -
12
Asymptotics of the entropy rate for a hidden Markov process
Published in Data Compression Conference (2005)“…We calculate the Shannon entropy rate of a binary hidden Markov process (HMP), of given transition rate and noise /spl epsiv/ (emission), as a series expansion…”
Get full text
Conference Proceeding -
13
The entropy of a binary hidden markov process
Published in Journal of statistical physics (01-11-2005)Get full text
Journal Article -
14
Finding motifs in promoter regions
Published in Journal of computational biology (01-04-2005)“…A central issue in molecular biology is understanding the regulatory mechanisms that control gene expression. The availability of whole genome sequences opens…”
Get more information
Journal Article -
15
Compressed sensing approach for high throughput carrier screen
Published in 2009 47th Annual Allerton Conference on Communication, Control, and Computing (Allerton) (01-09-2009)“…Carrier screens are widely used in medical genetics to prevent rare genetic disorders. Current detection methods are based on serial processing which is slow…”
Get full text
Conference Proceeding -
16
The Entropy of a Binary Hidden Markov Process
Published 23-07-2005“…The entropy of a binary symmetric Hidden Markov Process is calculated as an expansion in the noise parameter epsilon. We map the problem onto a one-dimensional…”
Get full text
Journal Article -
17
Bilorus'ke radjans'ke opovidannja
Published in World Literature Today (01-07-1980)Get full text
Book Review Journal Article