Search Results - "Zuidwijk, Marian J."
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Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats
Published in The Journal of clinical investigation (01-03-2008)“…Thyroid hormone is a critical determinant of cellular metabolism and differentiation. Precise tissue-specific regulation of the active ligand…”
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Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure
Published in American journal of physiology. Heart and circulatory physiology (01-03-2010)“…ROS have been implicated in the development of pathological ventricular hypertrophy and the ensuing contractile dysfunction. Using the rat monocrotaline (MCT)…”
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MicroRNA 214 Is a Potential Regulator of Thyroid Hormone Levels in the Mouse Heart Following Myocardial Infarction, by Targeting the Thyroid-Hormone-Inactivating Enzyme Deiodinase Type III
Published in Frontiers in endocrinology (Lausanne) (09-03-2016)“…Cardiac thyroid-hormone signaling is a critical determinant of cellular metabolism and function in health and disease. A local hypothyroid condition within the…”
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Thyroid Hormone-Regulated Cardiac microRNAs are Predicted to Suppress Pathological Hypertrophic Signaling
Published in Frontiers in endocrinology (Lausanne) (01-01-2014)“…Cardiomyocyte size in the healthy heart is in part determined by the level of circulating thyroid hormone (TH). Higher levels of TH induce ventricular…”
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H9c2 cardiomyoblasts produce thyroid hormone
Published in American Journal of Physiology: Cell Physiology (01-05-2008)“…Thyroid hormone acts on a wide range of tissues. In the cardiovascular system, thyroid hormone is an important regulator of cardiac function and cardiovascular…”
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Left-Ventricular Remodeling After Myocardial Infarction Is Associated with a Cardiomyocyte-Specific Hypothyroid Condition
Published in Endocrinology (Philadelphia) (01-02-2011)“…Myocardial infarction is associated with a cardiomyocyte-specific induction of type 3 deiodinase and a concomitant cellular hypothyroid condition. Similarities…”
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Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species
Published in Cardiovascular research (01-09-2007)“…Reactive oxygen species (ROS) have been implicated in the progression of ventricular hypertrophy to congestive heart failure. However, the source of increased…”
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Distinct myocardial effects of beta-blocker therapy in heart failure with normal and reduced left ventricular ejection fraction
Published in European heart journal (01-08-2009)“…Aims Left ventricular (LV) myocardial structure and function differ in heart failure (HF) with normal (N) and reduced (R) LV ejection fraction (EF). This…”
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RhoA-ROCK signaling is involved in contraction-mediated inhibition of SERCA2a expression in cardiomyocytes
Published in Pflügers Archiv (01-08-2009)“…In neonatal ventricular cardiomyocytes (NVCM), decreased contractile activity stimulates sarco-endoplasmic reticulum Ca 2+ -ATPase2a (SERCA2a), analogous to…”
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Left-Ventricular Remodeling After Myocardial Infarction Is Associated with a Cardiomyocyte-Specific Hypothyroid Condition
Published in The journal of clinical endocrinology and metabolism (01-01-2011)“…Endocrinology, published December 15, 2010, 10.1210/en.2010-0431…”
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Contractile arrest reveals calcium-dependent stimulation of SERCA2a mRNA expression in cultured ventricular cardiomyocytes
Published in Cardiovascular research (15-08-2004)“…Downregulation of sarco-endoplasmic reticulum calcium ATPase 2a (SERCA2a) expression is a critical marker of pathological myocardial hypertrophy. The effects…”
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Differential effects of thyroid hormone on the expression of sarcoplasmic reticulum Ca(2+)-ATPase isoforms in rat skeletal muscle fibers
Published in Biochemical and biophysical research communications (15-09-1994)“…Thyroid hormone increased the percentage of fibers expressing fast-type sarcoplasmic reticulum Ca(2+)-ATPase in the slow rat soleus muscle from 17% in the…”
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Fiber-specific regulation of Ca(2+)-ATPase isoform expression by thyroid hormone in rat skeletal muscle
Published in The American journal of physiology (01-12-1996)“…We studied the effect of thyroid hormone (3,5,3'-triiodo-L-thyronine, T3) on the expression of sarcoplasmic reticulum (SR) fast- and slow-type Ca(2+)-ATPase…”
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Modulation of SERCA2 expression by thyroid hormone and norepinephrine in cardiocytes: role of contractility
Published in The American journal of physiology (01-04-1997)“…Decreased expression of the cardiac slow-twitch sarcoplasmic reticulum Ca2+-adenosinetriphosphatase (SERCA2), a major determinant of Ca2+ homeostasis,…”
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Expression of MyoD in Cultured Primary Myotubes Is Dependent on Contractile Activity: Correlation with Phenotype-Specific Expression of a Sarcoplasmic Reticulum Ca2+-ATPase Isoform
Published in Biochemical and biophysical research communications (04-12-1996)“…Myogenic determination factors (MDF) have been implicated in the establishment and maintenance of the fast or slow phenotype in skeletal muscle, with MyoD…”
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Expression of MyoD in cultured primary myotubes is dependent on contractile activity: correlation with phenotype-specific expression of a sarcoplasmic reticulum Ca(2+)-ATPase isoform
Published in Biochemical and biophysical research communications (04-12-1996)“…Myogenic determination factors (MDF) have been implicated in the establishment and maintenance of the fast or slow phenotype in skeletal muscle, with MyoD…”
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