Search Results - "Zufferey, Rachel"

Lipidomics and anti-trypanosomatid chemotherapy by Biagiotti, Michael, Dominguez, Sedelia, Yamout, Nader, Zufferey, Rachel

“…Background Trypanosomatids such as Leishmania, Trypanosoma brucei and Trypanosoma cruzi belong to the order Kinetoplastida and are the source of many…”
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The Trypanosoma brucei dihydroxyacetonephosphate acyltransferase TbDAT is dispensable for normal growth but important for synthesis of ether glycerophospholipids by Zufferey, Rachel, Pirani, Karim, Cheung-See-Kit, Melanie, Lee, Sungsu, Williams, Tyler A, Chen, Daniel G, Hossain, Md Faruk

“…Glycerophospholipids are the most abundant constituents of biological membranes in Trypanosoma brucei, which causes sleeping sickness in humans and nagana in…”
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The Plasma Membrane Permease PfNT1 Is Essential for Purine Salvage in the Human Malaria Parasite Plasmodium falciparum by El Bissati, Kamal, Zufferey, Rachel, Witola, William H., Carter, Nicola S., Ullman, Buddy, Mamoun, Choukri Ben

“…The human malaria parasite Plasmodium falciparum relies on the acquisition of host purines for its survival within human erythrocytes. Purine salvage by the…”
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PfNT2, a Permease of the Equilibrative Nucleoside Transporter Family in the Endoplasmic Reticulum of Plasmodium falciparum by Downie, Megan J., El Bissati, Kamal, Bobenchik, April M., Nic Lochlainn, Laura, Amerik, Alexander, Zufferey, Rachel, Kirk, Kiaran, Ben Mamoun, Choukri

“…The survival and proliferation of the obligate intracellular malaria parasite Plasmodium falciparum require salvage of essential purines from the host. Genetic…”
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Candida albicans Csy1p Is a Nutrient Sensor Important for Activation of Amino Acid Uptake and Hyphal Morphogenesis by Brega, Elisa, Zufferey, Rachel, Mamoun, Choukri Ben

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The N-terminal domain and glycosomal localization of Leishmania initial acyltransferase LmDAT are important for lipophosphoglycan synthesis by Al-Ani, Gada K, Patel, Nipul, Pirani, Karim A, Zhu, Tongtong, Dhalladoo, Subbhalakshmi, Zufferey, Rachel

“…Ether glycerolipids of Leishmania major are important membrane components as well as building blocks of various virulence factors. In L. major, the first…”
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Ether Phospholipids and Glycosylinositolphospholipids Are Not Required for Amastigote Virulence or for Inhibition of Macrophage Activation by Leishmania major by Zufferey, Rachel, Allen, Simon, Barron, Tamara, Sullivan, Deborah R., Denny, Paul W., Almeida, Igor C., Smith, Deborah F., Turco, Salvatore J., Ferguson, Michael A.J., Beverley, Stephen M.

“…Ether phospholipids are major components of the membranes of humans and Leishmania. In protozoan parasites they occur separately or as part of the…”
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Leishmania major Expresses a Single Dihydroxyacetone Phosphate Acyltransferase Localized in the Glycosome, Important for Rapid Growth and Survival at High Cell Density and Essential for Virulence by Zufferey, Rachel, Mamoun, Choukri Ben

“…Despite major advances in the understanding of pathogenesis of the human protozoan parasite Leishmania major, little is known about the enzymes and the primary…”
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Unraveling the Mode of Action of the Antimalarial Choline Analog G25 in Plasmodium falciparum and Saccharomyces cerevisiae by ROGGERO, Rodolphe, ZUFFEREY, Rachel, MINCA, Mihaela, RICHIER, Eric, GALAS, Michele, VIAL, Henri, CHOUKRI BEN MAMOUN

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The Plasmodium falciparum PfGatp is an Endoplasmic Reticulum Membrane Protein Important for the Initial Step of Malarial Glycerolipid Synthesis by Santiago, Teresa C., Zufferey, Rachel, Mehra, Rajendra S., Coleman, Rosalind A., Mamoun, Choukri Ben

“…During its 48-h asexual life cycle within human erythrocytes, Plasmodium falciparum grows to many times its own size and divides to produce 16–32 new…”
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In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity by Zufferey, Rachel

“…Phosphatidylethanolamine methyltransferases are biosynthetic enzymes that catalyze the transfer of one or more methyl group(s) from S-adenosyl-L-methionine…”
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In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity by Zufferey, Rachel

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Assembly and Function of the Cytochrome cbb▪ Oxidase Subunits in Bradyrhizobium japonicum(∗) by Zufferey, Rachel, Preisig, Oliver, Hennecke, Hauke, Thöny-Meyer, Linda

“…The Bradyrhizobium japonicum cbb▪-type cytochrome oxidase, which supports microaerobic respiration, is a multisubunit enzyme encoded by the genes of the…”
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Characterization of Leishmania major phosphatidylethanolamine methyltransferases LmjPEM1 and LmjPEM2 and their inhibition by choline analogs by Bibis, Stergios S., Dahlstrom, Kelly, Zhu, Tongtong, Zufferey, Rachel

“…Leishmania phosphatidylethanolamine methyltransferases LmjPEM1 and LmjPEM2 convert phosphatidylethanolamine into phosphatidylcholine, localize at the…”
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The glycosomal alkyl-dihydroxyacetonephosphate synthase TbADS is essential for the synthesis of ether glycerophospholipids in procyclic trypanosomes by Lee, Sungsu, Cheung-See-Kit, Melanie, Williams, Tyler A., Yamout, Nader, Zufferey, Rachel

“…Glycerophospholipids are the main constituents of the biological membranes in Trypanosoma brucei, which causes sleeping sickness in humans. The present work…”
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Overproduction of theBradyrhizobium japonicum c-Type Cytochrome Subunits of thecbb3Oxidase inEscherichia coli by Arslan, Engin, Schulz, Henk, Zufferey, Rachel, Künzler, Peter, Thöny-Meyer, Linda

“…We report on a system to improve expression of maturec-type cytochromes inEscherichia coli.It is based on the use of plasmid pEC86 that expresses theE…”
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Characterization of a compensatory mutant of Leishmania major that lacks ether lipids but exhibits normal growth and G418 resistance by Zhu, Tongtong, Dhalladoo, Subbhalaskshmi, Bibis, Sergio, Zufferey, Rachel

“…Abstract only Ether glycerolipid biosynthesis in Leishmania major initiates with the acylation of dihydroxyacetonephosphate by the glycosomal…”
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Glycosomal localization of dihydroxyacetone phosphate acyltransferase LmDAT is important for lipophosphoglycan biosynthesis by Patel, Nipul, Zhu, Tongtong, Dhalladoo, Subbhalakshmi, Zufferey, Rachel

“…Abstract only Protozoan parasites of the genus Leishmania are the causative agents of several human and animal diseases collectively called leishmaniases. The…”
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The Glycerol‐3‐Phosphate Acyltransferase Tb GAT is Dispensable for Viability and the Synthesis of Glycerolipids in Trypanosoma brucei by Patel, Nipul, Pirani, Karim A., Zhu, Tongtong, Cheung‐See‐Kit, Melanie, Lee, Sungsu, Chen, Daniel G., Zufferey, Rachel

“…Glycerolipids are the main constituents of biological membranes in Trypanosoma brucei , which causes sleeping sickness in humans. Importantly, they occur as a…”
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The Glycerol-3-Phosphate Acyltransferase TbGAT is Dispensable for Viability and the Synthesis of Glycerolipids in Trypanosoma brucei by Patel, Nipul, Pirani, Karim A., Zhu, Tongtong, Cheung-See-Kit, Melanie, Lee, Sungsu, Chen, Daniel G., Zufferey, Rachel

“…Glycerolipids are the main constituents of biological membranes in Trypanosoma brucei, which causes sleeping sickness in humans. Importantly, they occur as a…”
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