Search Results - "Zucco, Flavia"

inter-laboratory study to evaluate the effects of medium composition on the differentiation and barrier function of Caco-2 cell lines by Zucco, F, Batto, A.F, Bises, G, Chambaz, J, Chiusolo, A, Consalvo, R, Cross, H, Dal Negro, G, Angelis, I. de, Fabre, G

“…Differentiated human intestinal Caco-2 cells are frequently used in toxicology and pharmacology as in vitro models for studies on intestinal barrier functions…”
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Optimisation of liver and intestine in vitro models for pharmacokinetics and pharmacodynamics studies. STREP – 037499 (Specific Targeted REsearch or innovation Project) by Zucco, Flavia

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Good Caco-2 cell culture practices by Natoli, Manuela, Leoni, Bruno D., D’Agnano, Igea, Zucco, Flavia, Felsani, Armando

“…► A novel protocol that improves Caco-2 cell in vitro differentiation is proposed. ► Cell growing density of Caco-2 cells affects properties of differentiated…”
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Cell growing density affects the structural and functional properties of Caco-2 differentiated monolayer by Natoli, Manuela, Leoni, Bruno D., D'Agnano, Igea, D'Onofrio, Mara, Brandi, Rossella, Arisi, Ivan, Zucco, Flavia, Felsani, Armando

“…The human intestinal Caco‐2 cell line has been extensively used as a model of the intestinal barrier. However, it is widely reported in literature that…”
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Differentiation of Caco-2 cells requires both transcriptional and post-translational down-regulation of Myc by Leoni, Bruno Daniele, Natoli, Manuela, Nardella, Marta, Bucci, Barbara, Zucco, Flavia, D'Agnano, Igea, Felsani, Armando

“…Caco-2 cancer cell line is widely used to reproduce in vitro the differentiation of absorptive enterocytes of human intestinal epithelium. This cell line, when…”
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The BIOSAFEPAPER project for in vitro toxicity assessments: Preparation, detailed chemical characterisation and testing of extracts from paper and board samples by Bradley, E.L., Honkalampi-Hämäläinen, U., Weber, A., Andersson, M.A., Bertaud, F., Castle, L., Dahlman, O., Hakulinen, P., Hoornstra, D., Lhuguenot, J.-C., Mäki-Paakkanen, J., Salkinoja-Salonen, M., Speck, D.R., Severin, I., Stammati, A., Turco, L., Zucco, F., von Wright, A.

“…Nineteen food contact papers and boards and one non-food contact board were extracted following test protocols developed within European Union funded project…”
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Toxicological profile of cereulide, the Bacillus cereus emetic toxin, in functional assays with human, animal and bacterial cells by Andersson, Maria A., Hakulinen, Pasi, Honkalampi-Hämäläinen, Ulla, Hoornstra, Douwe, Lhuguenot, Jean-Claude, Mäki-Paakkanen, Jorma, Savolainen, Martti, Severin, Isabelle, Stammati, Anna-Laura, Turco, Laura, Weber, Assi, von Wright, Atte, Zucco, Flavia, Salkinoja-Salonen, Mirja

“…Some strains of the endospore-forming bacterium Bacillus cereus produce a heat-stable ionophoric peptide, cereulide, of high human toxicity. We assessed cell…”
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Safety evaluation of food contact paper and board using chemical tests and in vitro bioassays: role of known and unknown substances by Honkalampi-Hämäläinen, U., Bradley, E.L., Castle, L., Severin, I., Dahbi, L., Dahlman, O., Lhuguenot, J.-C., Andersson, M.A., Hakulinen, P., Hoornstra, D., Mäki-Paakkanen, J., Salkinoja-Salonen, M., Turco, L., Stammati, A., Zucco, F., Weber, A., von Wright, A.

“…In vitro toxicological tests have been proposed as an approach to complement the chemical safety assessment of food contact materials, particularly those with…”
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Test procedures for obtaining representative extracts suitable for reliable in vitro toxicity assessment of paper and board intended for food contact by Bradley, E.L., Stammati, A., Salkinoja-Salonen, M., Andersson, M., Bertaud, F., Hoornstra, D., Zucco, F., Weber, A., Turco, L., Traussnig, H., Hakulinen, P., Speck, D.R., Von Wright, A.J., Honkalampi-Hämäläinen, U., Mäki-Paakkanen, J., Severin, I., Lhuguenot, J.-C., Dahlman, O.

“…This paper describes the use of a suite of extraction procedures applicable to the assessment of the in vitro toxicity of paper/board samples intended for…”
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Safety assessment of food-contact paper and board using a battery of short-term toxicity tests: European union BIOSAFEPAPER project by Severin, I, Dahbi, L, Lhuguenot, J-C, Andersson, M A, Hoornstra, D, Salkinoja-Salonen, M, Turco, L, Zucco, F, Stammati, A, Dahlman, O, Castle, L, Savolainen, M, Weber, A, Honkalampi-Hämäläinen, U, Von Wright, A

“…An European Union (EU)-funded project QLK1-CT-2001-00930 (BIOSAFEPAPER) involves the development, validation and intercalibration of a short-term battery of…”
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The '3Rs' Model and the Concept of Alternatives in Animal Research: A Questionnaire Survey by Vitale, Augusto, Pollo, Simone, Gayle, Vernon, Zucco, Flavia

“…It has been 45 years since Russell and Burch first proposed the concept of the '3Rs', yet it remains unclear how those individuals involved in animal research…”
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Cytostatic properties of a novel compound derived from Penicillium pinophilum: An in vitro study by STAMMATI, Annalaura, NICOLETTI, Rosario, DE STEFANO, Salvatore, ZAMPAGLIONI, Franco, ZUCCO, Flavia

“…3-O-Methylfunicone (OMF), a secondary metabolite produced by Penicillium pinophilum, inhibits the in vitro growth of plant pathogenic fungi. This specific…”
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Two in vitro models for gas-phase exposure to volatile compounds by BONSI, Paola, ZUCCO, Flavia, STAMMATI, Annalaura

“…Two experimental models suitable for the screening of volatile compounds were set up. The first consisted of a glass-chamber slide with eight wells, one…”
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Characterization of Furazolidone Apical-Related Effects to Human Polarized Intestinal Cells by De Angelis, Isabella, Vincentini, Olimpia, Brambilla, Gianfranco, Stammati, Annalaura, Zucco, Flavia

“…In studying the effects of furazolidone (FZ) on the human intestinal Caco-2 cell line grown on microporous membrane, we have previously demonstrated a higher…”
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Evidence for cytochrome P4501A2-mediated protein covalent binding of thiabendazole and for its passive intestinal transport: use of human and rabbit derived cells by Coulet, Myriam, Eeckhoutte, Claudine, Larrieu, Gilberte, Sutra, Jean-François, Alvinerie, Michel, Macé, Katherine, Pfeifer, Andrea, Zucco, Flavia, Laura Stammati, Anna, De Angelis, Isabella, Vignoli, Anna Lidia, Galtier, Pierre

“…Thiabendazole (TBZ), an anthelmintic and fungicide benzimidazole, was recently demonstrated to be extensively metabolized by cytochrome P450 (CYP) 1A2 in man…”
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Apoptosis evaluation in epithelial cells exposed to different chemicals : relevance of floating cells by TURCO, L, DE ANGELIS, I, STAMMATI, A, ZUCCO, F

“…The recent increase in understanding of cell death has promoted new approaches in toxicological studies, mainly those dealing with in vitro systems where the…”
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N-[5-nitro-2-furfurylidene]-3-amino-2-oxazolidinone activation by the human intestinal cell line Caco-2 monitored through noninvasive electron spin resonance spectroscopy by Rossi, L, De Angelis, I, Pedersen, J Z, Marchese, E, Stammati, A, Rotilio, G, Zucco, F

“…The pathways participating in the metabolism of the nitrofuran antimicrobial drug N-[5-nitro-2-furfurylidene]-3-amino-2-oxazolidinone (furazolidone) in intact…”
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Normal rat intestinal cells IEC-18 : characterization and transfection with immortalizing oncogenes by VINCENTINI, O, CIOTTA, C, BIGNAMI, M, STAMMATI, A, ZUCCO, F

“…IEC-18 cells, a cell line derived from the ileum of rat intestine, have the characteristics of normal cells since they have a contact inhibited cell growth, do…”
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Toxicology investigations with cell culture systems by Stammati, A P, Silano, V, Zucco, F

“…This review concerns some of the cell culture systems that are most frequently used in toxicology investigations. In particular, it sets out to evaluate the…”
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Studies of cytotoxicity and metabolic competence with the rat intestinal cell line IEC-17 by Di Folco, S, Stammati, A, Vittozzi, L, Zucco, F

“…The characterization of metabolic activity of intestinal cells in culture may be of particular interest for the study of the effects of food additives and…”
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