Search Results - "Zucco, Adrian"
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Personalized survival probabilities for SARS-CoV-2 positive patients by explainable machine learning
Published in Scientific reports (16-08-2022)“…Interpretable risk assessment of SARS-CoV-2 positive patients can aid clinicians to implement precision medicine. Here we trained a machine learning model to…”
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Readmissions, Postdischarge Mortality, and Sustained Recovery Among Patients Admitted to Hospital With Coronavirus Disease 2019 (COVID-19)
Published in Clinical infectious diseases (08-02-2023)“…Many interventional in-patient coronavirus disease 2019 (COVID-19) trials assess primary outcomes through day 28 post-randomization. Since a proportion of…”
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Associations of functional human leucocyte antigen class I groups with HIV viral load in a heterogeneous cohort
Published in AIDS (London) (01-09-2023)“…Human leucocyte antigen (HLA) class I alleles are the main host genetic factors involved in controlling HIV-1 viral load (VL). Nevertheless, HLA diversity has…”
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Association between ten-eleven methylcytosine dioxygenase 2 genetic variation and viral load in people with HIV
Published in AIDS (London) (01-03-2023)“…Identifying genetic factors that influence HIV-pathogenesis is critical for understanding disease pathways. Previous studies have suggested a role for the…”
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Chest x-ray imaging score is associated with severity of COVID-19 pneumonia: the MBrixia score
Published in Scientific reports (05-12-2022)“…Spatial resolution in existing chest x-ray (CXR)-based scoring systems for coronavirus disease 2019 (COVID-19) pneumonia is low, and should be increased for…”
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Human Immunotypes Impose Selection on Viral Genotypes Through Viral Epitope Specificity
Published in The Journal of infectious diseases (15-12-2021)“…Abstract Background Understanding the genetic interplay between human hosts and infectious pathogens is crucial for how we interpret virulence factors. Here,…”
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The association of human leukocyte antigen alleles with clinical disease progression in HIV-positive cohorts with varied treatment strategies
Published in AIDS (London) (01-04-2021)“…The Strategic Timing of AntiRetroviral Treatment (START) and Strategies for Management of Antiretroviral Therapy (SMART) trials demonstrated that ART can…”
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Association Between Single-Nucleotide Polymorphisms in HLA Alleles and Human Immunodeficiency Virus Type 1 Viral Load in Demographically Diverse, Antiretroviral Therapy–Naive Participants From the Strategic Timing of AntiRetroviral Treatment Trial
Published in The Journal of infectious diseases (13-09-2019)“…Abstract The impact of variation in host genetics on replication of human immunodeficiency virus type 1 (HIV-1) in demographically diverse populations remains…”
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Metabolic Profiling Early Post-Allogeneic Haematopoietic Cell Transplantation in the Context of CMV Infection
Published in Metabolites (22-08-2023)“…Immune dysfunction resulting from allogeneic haematopoietic stem cell transplantation (aHSCT) predisposes one to an elevated risk of cytomegalovirus (CMV)…”
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Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients
Published in Communications medicine (12-09-2022)“…Background The immune pathogenesis underlying the diverse clinical course of COVID-19 is poorly understood. Currently, there is an unmet need in daily clinical…”
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Author Correction: Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients
Published in Communications medicine (02-02-2023)Get full text
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Association between TET2 genetic variation and viral load in people living with HIV
Published in AIDS (London) (08-12-2022)Get full text
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Impact of Antibiotic Treatment on the Gut Microbiome and its Resistome in Hematopoietic Stem Cell Transplant Recipients
Published in The Journal of infectious diseases (28-06-2023)“…Abstract Antibiotic-resistant bacterial infections are increasingly an issue in allogenic hematopoietic stem cell transplant patients. How antibiotic treatment…”
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Readmissions, post-discharge mortality and sustained recovery among patients admitted to hospital with COVID-19
Published in Clinical infectious diseases (08-08-2022)Get full text
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The association of HLA alleles with clinical disease progression in HIV-positive cohorts with varied treatment strategies
Published in AIDS (London) (01-04-2021)Get full text
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29. Sustained Recovery in Patients Admitted to Hospital With COVID-19
Published in Open forum infectious diseases (04-12-2021)“…Abstract Background Several interventional Coronavirus Disease 2019 (COVID-19) studies assess outcomes at day 28, but this follow-up time can be too short,…”
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Erratum: Author Correction: Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients
Published in Communications medicine (2023)“…[This corrects the article DOI: 10.1038/s43856-022-00178-5.]…”
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Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients
Published in Communications medicine (12-09-2022)“…The immune pathogenesis underlying the diverse clinical course of COVID-19 is poorly understood. Currently, there is an unmet need in daily clinical practice…”
Get full text
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