Search Results - "Zuccari, Débora Aparecida Pires de Campos"
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Differentially expressed genes in giant cell tumor of bone
Published in Virchows Archiv : an international journal of pathology (01-04-2011)“…Giant cells tumors of bone (GCTB) are benign in nature but cause osteolytic destruction with a number of particular characteristics. These tumors can have…”
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2
Exosomes and Melatonin: Where Their Destinies Intersect
Published in Frontiers in immunology (11-06-2021)“…Cell-to-cell communication is a broad and complex process associated with regular stimuli to maintain healthy cell interactions. One of the agents capable of…”
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3
Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cells
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2019)“…Chalcones are valuable structures for drug discovery due to their broad bioactivity spectrum. In this study, we evaluated 20 synthetic chalcones against…”
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4
Melatonin Regulates Angiogenic and Inflammatory Proteins in MDA-MB-231 Cell Line and in Co-culture with Cancer-associated Fibroblasts
Published in Anti-cancer agents in medicinal chemistry (01-11-2016)“…Cancer-associated fibroblast (CAFs) are the most abundant cells in the tumor microenvironment, able to secrete growth factors and act on tumor progression…”
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5
Evaluation of doxorubicin in three-dimensional culture of breast cancer cells and the response in PI3K/AKT/PTEN signaling pathways: a pilot study
Published in Women & health (03-07-2022)“…Breast cancer (BC) has a high mortality rate, which is attributed to the absence of effective treatment markers. Doxorubicin (DOX) was evaluated by molecular…”
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Melatonin decreases breast cancer metastasis by modulating Rho-associated kinase protein-1 expression
Published in Journal of pineal research (01-01-2016)“…The occurrence of metastasis, an important breast cancer prognostic factor, depends on cell migration/invasion mechanisms, which can be controlled by…”
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Melatonin Regulates Angiogenic Factors under Hypoxia in Breast Cancer Cell Lines
Published in Anti-cancer agents in medicinal chemistry (01-01-2016)“…Angiogenesis is the process of new blood vessel formation, regulated by a number of pro- and antiangiogenic factors and usually begins in response to hypoxia…”
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Molecular markers of angiogenesis and metastasis in lines of oral carcinoma after treatment with melatonin
Published in Anti-cancer agents in medicinal chemistry (01-01-2014)“…Oral cancer is the most common type of head and neck cancer and its high rate of mortality and morbidity is closely related to the processes of angiogenesis…”
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Inhibition of Epithelial-Mesenchymal Transition and Metastasis by Combined TGFbeta Knockdown and Metformin Treatment in a Canine Mammary Cancer Xenograft Model
Published in Journal of mammary gland biology and neoplasia (01-03-2017)“…Epithelial mesenchymal transition (EMT) is a process by which epithelial cells acquire mesenchymal properties, generating metastases. Transforming growth…”
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10
Inhibition of Epithelial-mesenchymal Transition in Response to Treatment with Metformin and Y27632 in Breast Cancer Cell Lines
Published in Anti-cancer agents in medicinal chemistry (01-07-2017)“…ROCK-1 expression is associated with the malignant character of tumors, while inhibiting this molecule results in a significant suppression of tumor…”
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11
Effect of Curcumin on Pro-angiogenic Factors in the Xenograft Model of Breast Cancer
Published in Anti-cancer agents in medicinal chemistry (01-01-2015)“…The formation of a new blood vessel is stimulated by angiogenic factors. Curcumin, which is the active ingredient of the spice plant Curcuma longa L and is…”
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12
Effect of melatonin on tumor growth and angiogenesis in xenograft model of breast cancer
Published in PloS one (09-01-2014)“…As neovascularization is essential for tumor growth and metastasis, controlling angiogenesis is a promising tactic in limiting cancer progression. Melatonin…”
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13
Effect of Melatonin in Epithelial Mesenchymal Transition Markers and Invasive Properties of Breast Cancer Stem Cells of Canine and Human Cell Lines
Published in PloS one (02-03-2016)“…Cancer stem cells (CSCs) have been associated with metastasis and therapeutic resistance and can be generated via epithelial mesenchymal transition (EMT). Some…”
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14
The proteomic landscape of ovarian cancer cells in response to melatonin
Published in Life sciences (1973) (01-04-2022)“…Ovarian cancer (OC) is the most lethal gynecological malignancy with a highly negative prognosis. Melatonin is an indoleamine secreted by the pineal gland…”
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15
Melatonin-Loaded Nanocarriers: New Horizons for Therapeutic Applications
Published in Molecules (Basel, Switzerland) (10-06-2021)“…The use of nanosized particles has emerged to facilitate selective applications in medicine. Drug-delivery systems represent novel opportunities to provide…”
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16
RNA-Seq transcriptome analysis shows anti-tumor actions of melatonin in a breast cancer xenograft model
Published in Scientific reports (30-01-2019)“…Melatonin is a pleiotropic anti-cancer molecule that controls cancer growth by multiple mechanisms. RNA-Seq can potentially evaluate therapeutic response and…”
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Efficacy of melatonin, IL-25 and siIL-17B in tumorigenesis-associated properties of breast cancer cell lines
Published in Life sciences (1973) (15-08-2017)“…Mammary tumorigenesis can be modulated by melatonin, which has oncostatic action mediated by multiple mechanisms, including the inhibition of the activity of…”
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Evaluation of melatonin and AFMK levels in women with breast cancer
Published in Endocrine (01-10-2018)“…Purpose Changes in the circadian rhythm may contribute to the development of cancer and are correlated with the high risk of breast cancer (BC) in night…”
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Liquid Biopsy as a Diagnostic and Prognostic Tool for Women and Female Dogs with Breast Cancer
Published in Cancers (19-10-2021)“…Breast cancer (BC) is the malignant neoplasm with the highest mortality rate in women and female dogs are good models to study BC. We investigated the efficacy…”
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Decoding Hidden Messengers: Proteomic Profiling of Exosomes in Mammary Cancer Research
Published in Biomedicines (01-10-2023)“…Cancer is a complex and heterogeneous disease, influenced by various factors that affect its progression and response to treatment. Although a…”
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