Search Results - "Zubler, Rudolf"

APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa by Huard, Bertrand, McKee, Thomas, Bosshard, Carine, Durual, Stéphane, Matthes, Thomas, Myit, Samir, Donze, Olivier, Frossard, Christophe, Chizzolini, Carlo, Favre, Christiane, Zubler, Rudolf, Guyot, Jean Philippe, Schneider, Pascal, Roosnek, Eddy

“…The bone marrow constitutes a favorable environment for long-lived antibody-secreting plasma cells, providing blood-circulating antibody. Plasma cells are also…”
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High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors by Salmon, Patrick, Kindler, Vincent, Ducrey, Odile, Chapuis, Bernard, Zubler, Rudolf H., Trono, Didier

“…Recent experiments point to the great value of lentiviral vectors for the transduction of human hematopoietic stem cells (hHSCs). Vectors used so far, however,…”
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Ex vivo expansion of haematopoietic stem cells and gene therapy development by Zubler, Rudolf H

“…The results of a research project on ex vivo expansion of human haematopoietic stem cells (HSC) and development of gene therapy, funded by the Swiss National…”
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Naive and memory B cells in T-cell-dependent and T-independent responses by Zubler, R H

“…This review focuses on the properties and roles of distinct subsets among the primary and the memory B lymphocytes regarding their contribution to…”
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Efficient transduction of primary human B lymphocytes and nondividing myeloma B cells with HIV-1–derived lentiviral vectors by Bovia, Fabrice, Salmon, Patrick, Matthes, Thomas, Kvell, Krisztian, Nguyen, Tuan H., Werner-Favre, Christiane, Barnet, Marc, Nagy, Monika, Leuba, Florence, Arrighi, Jean-François, Piguet, Vincent, Trono, Didier, Zubler, Rudolf H.

“…We studied the transduction of primary human B lymphocytes and myeloma cells with lentiviral vectors. In peripheral blood B cells that had been activated with…”
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Transduction of CpG DNA-Stimulated Primary Human B Cells with Bicistronic Lentivectors by Kvell, Krisztian, Nguyen, Tuan H, Salmon, Patrick, Glauser, Frédéric, Werner-Favre, Christiane, Barnet, Marc, Schneider, Pascal, Trono, Didier, Zubler, Rudolf H

“…Recently, using HIV-1-derived lentivectors, we obtained efficient transduction of primary human B lymphocytes cocultured with murine EL-4 B5 thymoma cells, but…”
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TNF‐α induces the generation of Langerin/(CD207)+ immature Langerhans‐type dendritic cells from both CD14–CD1a– and CD14+CD1a– precursors derived from CD34+ cord blood cells by Arrighi, Jean‐François, Soulas, Caroline, Hauser, Conrad, Saeland, Sem, Chapuis, Bernard, Zubler, Rudolf H., Kindler, Vincent

“…CD34+ cell‐derived hematopoietic precursors amplified with FLT3‐ligand, thrombopoietin and stem cell factor became, after a 6‐day induction with GM‐CSF, IL‐4…”
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Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells by Salmon, Patrick, Arrighi, Jean-François, Piguet, Vincent, Chapuis, Bernard, Zubler, Rudolf H., Trono, Didier, Kindler, Vincent

“…Background Genetically engineered dendritic cells (DC) presenting specific antigens to T cells may be of great interest for immunotherapy. For this reason, the…”
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High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors by Salmon, Patrick, Kindler, Vincent, Ducrey, Odile, Chapuis, Bernard, Zubler, Rudolf H., Trono, Didier

“…Recent experiments point to the great value of lentiviral vectors for the transduction of human hematopoietic stem cells (hHSCs). Vectors used so far, however,…”
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Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes by Lowenthal, John W, Zubler, Rudolf H, Nabholz, Markus, MacDonald, H. Robson

“…Interleukin-2 (IL-2) is a T-cell-derived polypeptide hormone of 133 amino acids which exerts its growth-promoting activity via a surface receptor. Originally,…”
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Differential induction of T cell cytokine mRNA in Epstein-Barr virus-transformed B cell clones: constitutive and inducible expression of interleukin-4 mRNA by Tang, H, Matthes, T, Carballido-Perrig, N, Zubler, R H, Kindler, V

“…Clones of human B lymphocytes, obtained after immortalization with Epstein-Barr virus (EBV) of single CD19+ B cells and expansion in the absence of human T…”
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FAS Engagement Induces the Maturation of Dendritic Cells (Dcs), the Release of Interleukin (Il)-1β, and the Production of Interferon γ in the Absence of IL-12 during Dc–T Cell Cognate Interaction: A New Role for FAS Ligand in Inflammatory Responses by Rescigno, Maria, Piguet, Vincent, Valzasina, Barbara, Lens, Suzanne, Zubler, Rudolf, French, Lars, Kindler, Vincent, Tschopp, Jurg, Ricciardi-Castagnoli, Paola

“…Ligation of the Fas (CD95) receptor leads to an apoptotic death signal in T cells, B cells, and macrophages. However, human CD34 + –derived dendritic cells…”
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Ex vivo expansion of hematopoietic stem cells and gene therapy development by Zubler, Rudolf H

“…The results of a research project on ex vivo expansion of human haematopoietic stem cells (HSC) and development of gene therapy, funded by the Swiss National…”
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Introduction by Zubler, Rudolf

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Introduction by Zubler, Rudolf

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APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa by Huard, Bertrand, McKee, Thomas, Bosshard, Carine, Durual, Stéphane, Matthes, Thomas, Myit, Samir, Donze, Olivier, Frossard, Christophe, Chizzolini, Carlo, Favre, Christiane, Zubler, Rudolf, Guyot, Jean Philippe, Schneider, Pascal, Roosnek, Eddy

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Long-Term Culture of Human CD34+ Progenitors With FLT3-Ligand, Thrombopoietin, and Stem Cell Factor Induces Extensive Amplification of a CD34−CD14− and a CD34−CD14+ Dendritic Cell Precursor by Arrighi, Jean-François, Hauser, Conrad, Chapuis, Bernard, Zubler, Rudolf H., Kindler, Vincent

“…Current in vitro culture systems allow the generation of human dendritic cells (DCs), but the output of mature cells remains modest. This contrasts with the…”
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IgG subclass switch capacity is low in switched and in IgM‐only, but high in IgD+IgM+, post‐germinal center (CD27+) human B cells by Werner‐Favre, Christiane, Bovia, Fabrice, Schneider, Pascal, Holler, Nils, Barnet, Marc, Kindler, Vincent, Tschopp, Jürg, Zubler, Rudolf H.

“…Recent studies have shown that in humans the germinal center reactions produce three types of V(D)J mutated B cells in similar proportions, i.e. Ig‐switched,…”
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Cytokine mRNA expression during an in vitro response of human B lymphocytes : kinetics of B cell tumor necrosis factor α, interleukin (IL)6, IL-10, and transforming growth factor β1 mRNAs by MATTHES, T, WERNER-FAVRE, C, HUAYANG TANG, XIAOHONG ZHANG, KINDLER, V, ZUBLER, R. H

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FAS Engagement Induces the Maturation of Dendritic Cells (Dcs), the Release of Interleukin (Il)-1β, and the Production of Interferon γ in the Absence of IL-12 during Dc–T Cell Cognate Interaction by Rescigno, Maria, Piguet, Vincent, Valzasina, Barbara, Lens, Suzanne, Zubler, Rudolf, French, Lars, Kindler, Vincent, Tschopp, Jurg, Ricciardi-Castagnoli, Paola

“…Ligation of the Fas (CD95) receptor leads to an apoptotic death signal in T cells, B cells, and macrophages. However, human CD34+–derived dendritic cells (DCs)…”
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