Search Results - "Zou, Zhilin"

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  1. 1

    mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges by Zou, Zhilin, Tao, Tao, Li, Hongmei, Zhu, Xiao

    Published in Cell & bioscience (10-03-2020)
    “…Mammalian target of rapamycin (mTOR) regulates cell proliferation, autophagy, and apoptosis by participating in multiple signaling pathways in the body…”
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    Journal Article
  2. 2

    Targeting ferroptosis in hepatocellular carcinoma by Mo, Yuqian, Zou, Zhilin, Chen, Erbao

    Published in Hepatology international (01-02-2024)
    “…Hepatocellular carcinoma (HCC) is a common malignant tumor with complex survival mechanism and drug resistance, resulting in cancer-related high mortality in…”
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    Journal Article
  3. 3

    Sliding Mode Control for Nonlinear Discrete Networked Cascade Control Systems With Uncertain Delay by Du, Zhaoping, Zou, Zhilin, Ye, Hui, Li, Jianzhen

    “…In this paper, the problems of modeling and sliding mode control for a class of nonlinear discrete networked cascade control systems (NCCSs) are studied…”
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    Journal Article
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    Identification and validation of a fatty acid metabolism-related lncRNA signature as a predictor for prognosis and immunotherapy in patients with liver cancer by Chen, Erbao, Yi, Jing, Jiang, Jing, Zou, Zhilin, Mo, Yuqian, Ren, Qingqi, Lin, Zewei, Lu, Yi, Zhang, Jian, Liu, Jikui

    Published in BMC cancer (04-10-2022)
    “…Abstract Background Fatty acid (FA) metabolism is considered the emerging cause of tumor development and metastasis, driving poor prognosis. Long non-coding…”
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    Journal Article
  6. 6

    CRISPR-CasRx-mediated disruption of Aqp1/Adrb2/Rock1/Rock2 genes reduces intraocular pressure and retinal ganglion cell damage in mice by Yao, Mingyu, Zeng, Zhenhai, Li, Siheng, Zou, Zhilin, Chen, Zhongxing, Chen, Xinyi, Gao, Qingyi, Zhao, Guoli, Chen, Aodong, Li, Zheng, Wang, Yiran, Ning, Rui, McAlinden, Colm, Zhou, Xingtao, Huang, Jinhai

    Published in Nature communications (30-07-2024)
    “…Glaucoma affects approximately 80 million individuals worldwide, a condition for which current treatment options are inadequate. The primary risk factor for…”
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    Journal Article
  7. 7

    Predictive value of a stemness-based classifier for prognosis and immunotherapy response of hepatocellular carcinoma based on bioinformatics and machine-learning strategies by Chen, Erbao, Zou, Zhilin, Wang, Rongyue, Liu, Jie, Peng, Zhen, Gan, Zhe, Lin, Zewei, Liu, Jikui

    Published in Frontiers in immunology (17-04-2024)
    “…Significant advancements have been made in hepatocellular carcinoma (HCC) therapeutics, such as immunotherapy for treating patients with HCC. However, there is…”
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    Journal Article
  8. 8

    Clinical and Prognostic Pan-Cancer Analysis of N6-Methyladenosine Regulators in Two Types of Hematological Malignancies: A Retrospective Study Based on TCGA and GTEx Databases by Zhang, Xiangsheng, Zhong, Liye, Zou, Zhilin, Liang, Guosheng, Tang, Zhenye, Li, Kai, Tan, Shuzhen, Huang, Yongmei, Zhu, Xiao

    Published in Frontiers in oncology (18-03-2021)
    “…N6-methyladenosine (m6A) is one of the most active modification factors of mRNA, which is closely related to cell proliferation, differentiation, and tumor…”
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    Journal Article
  9. 9

    CDCA8 induced by NF-YA promotes hepatocellular carcinoma progression by regulating the MEK/ERK pathway by Chen, Erbao, He, Yu, Jiang, Jing, Yi, Jing, Zou, Zhilin, Song, Qiuzi, Ren, Qingqi, Lin, Zewei, Lu, Yi, Liu, Jikui, Zhang, Jian

    Published in Experimental hematology & oncology (13-01-2023)
    “…Hepatocellular carcinoma (HCC) is one of the most lethal malignant tumors. Cell division cycle associated 8 (CDCA8) is an important multifactorial regulator in…”
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    Journal Article
  10. 10

    Genome Editing VEGFA Prevents Corneal Neovascularization In Vivo by Zeng, Zhenhai, Li, Siheng, Ye, Xiuhong, Wang, Yiran, Wang, Qinmei, Chen, Zhongxing, Wang, Ziqian, Zhang, Jun, Wang, Qing, Chen, Lu, Zhang, Shuangzhe, Zou, Zhilin, Lin, Meimin, Chen, Xinyi, Zhao, Guoli, McAlinden, Colm, Lei, Hetian, Zhou, Xingtao, Huang, Jinhai

    Published in Advanced science (01-07-2024)
    “…Corneal neovascularization (CNV) is a common clinical finding seen in a range of eye diseases. Current therapeutic approaches to treat corneal angiogenesis, in…”
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    Journal Article
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    The Regulators Associated With N6-Methyladenosine in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma Reveal New Clinical and Prognostic Markers by Tan, Shuzhen, Li, Zesong, Li, Kai, Li, Yingqi, Liang, Guosheng, Tang, Zhenye, Kang, Jianhao, Chen, Wenqing, Li, Minhua, Zou, Zhilin, Pi, Guoliang, Zhu, Xiao

    “…N6-methyladenosine (m A) methylation is of significant importance in the initiation and progression of tumors, but how specific genes take effect in different…”
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    Journal Article
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    Synthesis, characterization, cellular uptake and apoptosis-inducing properties of two highly cytotoxic cyclometalated ruthenium(II) β-carboline complexes by Chen, Jincan, Peng, Fa, Zhang, Yao, Li, Baojun, She, Ji, Jie, Xinming, Zou, Zhilin, Chen, Man, Chen, Lanmei

    Published in European journal of medicinal chemistry (10-11-2017)
    “…Two new cyclometalated Ru(II) complexes of the general formula [Ru(N-N)2(1-Ph-βC)](PF6), where N–N = 4,4′-dimethyl-2,2′-bipyridine (dmb, Ru1), 2,2′-bipyridine…”
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    Journal Article
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    Joint Registration for Denoising in Optical Coherence Tomography Angiography by Zou, Zhilin

    Published 01-01-2022
    “…The quality of optical coherence tomography angiography (OCTA) images is often hurt by the noises due to unavoidable subject motion and system jitters. Current…”
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    Dissertation
  17. 17

    TopoTxR: A topology-guided deep convolutional network for breast parenchyma learning on DCE-MRIs by Wang, Fan, Zou, Zhilin, Sakla, Nicole, Partyka, Luke, Rawal, Nil, Singh, Gagandeep, Zhao, Wei, Ling, Haibin, Huang, Chuan, Prasanna, Prateek, Chen, Chao

    Published in Medical image analysis (01-01-2025)
    “…Characterization of breast parenchyma in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a challenging task owing to the complexity of…”
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    Journal Article
  18. 18

    Cytotoxicity in vitro, cellular uptake, localization and apoptotic mechanism studies induced by ruthenium(II) complex by Chen, Jincan, Zhang, Yao, Li, Guodong, Peng, Fa, Jie, Xinming, She, Ji, Dongye, Guangzhi, Zou, Zhilin, Rong, Shiwen, Chen, Lanmei

    Published in Journal of biological inorganic chemistry (01-03-2018)
    “…Ruthenium-based complexes have been regarded as one of the most potential metal-based candidates for anticancer therapy. Herein, two ruthenium (II)…”
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    Journal Article
  19. 19

    A novel hepatocellular carcinoma-specific mTORC1-related signature for anticipating prognosis and immunotherapy by Chen, Erbao, Mo, Yuqian, Yi, Jing, Liu, Jie, Luo, Ting, Li, Zheng, Lin, Zewei, Hu, Yibing, Zou, Zhilin, Liu, Jikui

    Published in Aging (Albany, NY.) (30-08-2023)
    “…Tumor oncogenesis, cancer metastasis, and immune evasion were substantially impacted by the mammalian target of the rapamycin complex 1 (mTORC1) pathway…”
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    Journal Article
  20. 20

    The pan-cancer analysis of the two types of uterine cancer uncovered clinical and prognostic associations with m6A RNA methylation regulators by Zou, Zhilin, Zhou, Shuguang, Liang, Guosheng, Tang, Zhenye, Li, Kai, Tan, Shuzhen, Zhang, Xiangsheng, Zhu, Xiao

    Published in Molecular omics (14-06-2021)
    “…The role of m6A RNA methylation modification in uterine cancer has not been studied until now. We explored the relationship between m6A regulators and clinical…”
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    Journal Article