Search Results - "Zou, Ying S"

Non-cutaneous syncytial myoepitheliomas are identical to cutaneous counterparts: a clinicopathologic study of 24 tumors occurring at diverse locations by Wangsiricharoen, Sintawat, Gjeorgjievski, Sandra G., Bahrami, Armita, Torres-Mora, Jorge, Zou, Ying S., Michal, Michael, Charville, Gregory W., Gross, John M.

“…Aims Cutaneous syncytial myoepithelioma (CSM) is a rare myoepithelioma variant of skin, characterized by intradermal syncytial growth of spindle cells with a…”
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HER2 amplification by next-generation sequencing to identify HER2-positive invasive breast cancer with negative HER2 immunohistochemistry by Morsberger, Laura, Pallavajjala, Aparna, Long, Patty, Hardy, Melanie, Park, Rebecca, Parish, Rebecca, Nozari, Azin, Zou, Ying S.

“…Abstract Background Human epidermal growth factor receptor 2 (HER2 ) positive breast carcinomas due to HER2 amplification are associated with aggressive…”
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A comprehensive approach to evaluate genetic abnormalities in multiple myeloma using optical genome mapping by Zou, Ying S., Klausner, Melanie, Ghabrial, Jen, Stinnett, Victoria, Long, Patty, Morsberger, Laura, Murry, Jaclyn B., Beierl, Katie, Gocke, Christopher D., Xian, Rena R., Toomer, Kevin H., Ye, Jing Christine, Orlowski, Robert Z., Huff, Carol Ann, Ali, Syed Abbas, Imus, Philip H., Gocke, Christian B., Tang, Guilin

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Donor cell-derived genetic abnormalities after sex mismatched allogeneic cell transplantation: a unique challenge of donor cell leukemia by Klausner, Melanie, Phan, Brian, Morsberger, Laura, Parish, Rebecca, Shane, Alison, Park, Rebecca, Gocke, Christopher D., Xian, Rena R., Jones, Rick John, Bolaños-Meade, Javier, Gondek, Lukasz P., Phan, Michael, Zou, Ying S.

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1q jumping translocation as a biomarker in myeloid malignancy: frequently mutated genes associated with bad prognosis and low survival by Halper-Stromberg, Eitan, Stinnett, Victoria, Morsberger, Laura, Pallavajjala, Aparna, Levis, Mark J, DeZern, Amy E, Lei, Michelle, Phan, Brian, Xian, Rena R, Gocke, Christopher D, Tang, Guilin, Zou, Ying S

“…1q jumping translocation (JT) is rare and its molecular profiles in myeloid malignancies are not well-known. This study evaluated gene mutations in 1q-JT…”
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An Integrated Approach Including CRISPR/Cas9-Mediated Nanopore Sequencing, Mate Pair Sequencing, and Cytogenomic Methods to Characterize Complex Structural Rearrangements in Acute Myeloid Leukemia by Phan, Michael, Gomes, Maria A, Stinnett, Victoria, Morsberger, Laura, Hoppman, Nicole L, Pearce, Kathryn E, Smith, Kirstin, Phan, Brian, Jiang, Liqun, Zou, Ying S

“…Complex structural chromosome abnormalities such as chromoanagenesis have been reported in acute myeloid leukemia (AML). They are usually not well…”
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Progenitor cell line (hPheo1) derived from a human pheochromocytoma tumor by Ghayee, Hans K, Bhagwandin, Vikash J, Stastny, Victor, Click, Arielle, Ding, Liang-Hao, Mizrachi, Dario, Zou, Ying S, Chari, Raj, Lam, Wan L, Bachoo, Robert M, Smith, Alice L, Story, Michael D, Sidhu, Stan, Robinson, Bruce G, Nwariaku, Fiemu E, Gazdar, Adi F, Auchus, Richard J, Shay, Jerry W

“…Pheochromocytomas are rare tumors generally arising in the medullary region of the adrenal gland. These tumors release excessive epinephrine and norepinephrine…”
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Whole gene duplication of the PQBP1 gene in syndrome resembling Renpenning by Flynn, Maureen, Zou, Ying S., Milunsky, Aubrey

“…Renpenning syndrome is a well‐described X‐linked condition associated with multiple congenital anomalies and intellectual disability [OMIM 309500]. Typical…”
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Characterization of Aneuploid Populations with Trisomy 7 and 20 Derived from Diploid Human Colonic Epithelial Cells by Ly, Peter, Eskiocak, Ugur, Kim, Sang B, Roig, Andres I, Hight, Suzie K, Lulla, Dypti R, Zou, Ying S, Batten, Kimberly, Wright, Woodring E, Shay, Jerry W

“…Abstract Chromosomal instability leading to aneuploidy occurs in most sporadic colorectal cancers (CRCs) and is believed to be an early driving force in…”
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Live‐born autosomal ring chromosomes at the Johns Hopkins Hospital Cytogenomics Laboratory: Case series—Spanning 52 years of experience in a single center by Kushwaha, Shivani, Stinnett, Victoria, Zou, Ying S., Murry, Jaclyn B.

“…Ring chromosomes (RCs) are a structural aberration that can be tolerated better in acrocentric or gonosomal chromosomes. Complete RCs arise from…”
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EWSR1::WT1 Fusions in Neoplasms Other Than Conventional Desmoplastic Small Round Cell Tumor: Three Tumors Occurring Outside the Female Genital Tract by Warmke, Laura M., Perret, Raul, Ledoux, Pauline, Michot, Audrey, Italiano, Antoine, Zou, Ying S., Matoso, Andres, Argani, Pedram, Ulbright, Thomas M., Baumhoer, Daniel, Ameline, Baptiste, Gross, John M.

“…Desmoplastic small round cell tumor (DSRCT) is a high-grade, primitive round cell sarcoma classically associated with prominent desmoplastic stroma,…”
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Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response by Seppälä, Toni T, Zimmerman, Jacquelyn W, Suri, Reecha, Zlomke, Haley, Ivey, Gabriel D, Szabolcs, Annamaria, Shubert, Christopher R, Cameron, John L, Burns, William R, Lafaro, Kelly J, He, Jin, Wolfgang, Christopher L, Zou, Ying S, Zheng, Lei, Tuveson, David A, Eshlemann, James R, Ryan, David P, Kimmelman, Alec C, Hong, Theodore S, Ting, David T, Jaffee, Elizabeth M, Burkhart, Richard A

“…Patient-derived organoids (PDO) are a promising technology to support precision medicine initiatives for patients with pancreatic ductal adenocarcinoma (PDAC)…”
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Twin/Multiple Gestations With a Hydatidiform Mole: Clinicopathologic Analysis of 21 Cases With Emphasis on Molecular Genotyping and Parental Contribution by Xing, Deyin, Adams, Emily, Zou, Ying S., Morsberger, Laura, Scanga, Lori R., Gao, Faye F., Barker, Norman, Vang, Russell, Ronnett, Brigitte M.

“…Complete hydatidiform moles (CHMs) and partial hydatidiform moles (PHMs) are abnormal gestations characterized by vesicular chorionic villi accompanied by…”
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Detection of an atypical BCR::ABL1 fusion in a patient with secondary B-cell acute lymphoblastic leukemia/lymphoma following multiple myeloma treatment by Miller, Karin, Webster, Jonathan, Imus, Philip, Ament, Candice, Hardy, Melanie, Zou, Ying S.

“…Secondary hematologic malignancies, such as B-cell acute lymphoblastic leukemia/lymphoma (B-ALL), have been reported following multiple myeloma. Tyrosine…”
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ERBB2/ ERBB3-mutated S100/ SOX10-positive unclassified high-grade uterine sarcoma: first detailed description of a novel entity by Agaimy, Abbas, Dermawan, Josephine K., Haller, Florian, Semrau, Sabine, Meidenbauer, Norbert, Stoehr, Robert, Lax, Sigurd, Hartmann, Arndt, Zou, Ying S., Xing, Deyin, Tögel, Lars, Gross, John M., Michal, Michael

“…With the increasing use of innovative next generation sequencing (NGS) platforms in routine diagnostic and research settings, the genetic landscape of uterine…”
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Myxoid epithelioid smooth muscle tumor of the vulva: A distinct entity with MEF2D::NCOA2 gene fusion by Warmke, Laura M., Mustafa, Amin, Zou, Ying S., Davis, Jessica L., Ulbright, Thomas M., Segura, Sheila E.

“…Smooth muscle tumors are the most common mesenchymal tumors of the female genital tract, including the vulva. Since vulvar smooth muscle tumors are rare, our…”
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Diagnostic Utility of Gene Fusion Panel to Detect Gene Fusions in Fresh and Formalin-Fixed, Paraffin-Embedded Cancer Specimens by Haley, Lisa, Parimi, Vamsi, Jiang, Liqun, Pallavajjala, Aparna, Hardy, Melanie, Yonescu, Raluca, Morsberger, Laura, Stinnett, Victoria, Long, Patty, Zou, Ying S., Gocke, Christopher D.

“…Somatic gene fusions are common in leukemias/lymphomas and solid tumors. The detection of gene fusions is crucial for diagnosis. NanoString fusion technology…”
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Undifferentiated Round Cell Sarcoma With CRTC1::SS18 Fusion: Expanding Clinicopathologic Features of a Rare Translocation Sarcoma With Prominent Desmoplastic Stroma by Warmke, Laura M., Strike, Sophia A., Fayad, Laura M., Ahlawat, Shivani, Liu, Yajuan J., Mata, Douglas A., Rooper, Lisa, Baraban, Ezra, Zou, Ying S., Gross, John M.

“…Undifferentiated round cell sarcomas (URCS) represent a diverse group of tumors, including conventional Ewing sarcoma, round cell sarcoma with…”
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Laboratory perspectives in the development of polygenic risk scores for disease: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG) by Reddi, Honey V., Wand, Hannah, Funke, Birgit, Zimmermann, Michael T., Lebo, Matthew S., Qian, Emily, Shirts, Brian H., Zou, Ying S., Zhang, Bing M., Rose, Nancy C., Abu-El-Haija, Aya

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Novel CRTC1::MRTFB(MKL2) Gene Fusion Detected in Myxoid Mesenchymal Neoplasms With Myogenic Differentiation Involving Bone and Soft Tissues by Warmke, Laura M., Collier, Christopher D., Niziolek, Paul J., Davis, Jessica L., Zou, Ying S., Michal, Michael, Bell, Robert C., Policarpio-Nicolas, Maria Luisa C., Cheng, Yu-Wei, Duckworth, Lauren, Dermawan, Josephine K., Fritchie, Karen J., Dehner, Carina A.

“…Appropriate classification of fusion-driven bone and soft tissue neoplasms continues to evolve, often relying on the careful integration of morphologic…”
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