Search Results - "Zou, Yaoyu"
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The morphokinetic signature of human blastocysts with mosaicism and the clinical outcomes following transfer of embryos with low-level mosaicism
Published in Journal of ovarian research (09-01-2024)“…Genetic mosaicism is commonly observed in human blastocysts. Embryos' morphokinetic feature observed from time-lapse monitoring (TLM) is helpful to predict the…”
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Impacts of vitrification on the transcriptome of human ovarian tissue in patients with gynecological cancer
Published in Frontiers in genetics (17-03-2023)“…This study investigated the effects of a vitrification/warming procedure on the mRNA transcriptome of human ovarian tissues. Human ovarian tissues were…”
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Hepatic Dyrk1b impairs systemic glucose homeostasis by modulating Wbp2 expression in a kinase activity-dependent manner
Published in Heliyon (15-09-2024)“…Patients with gain-of-function mutations of Dyrk1b have higher fasting blood glucose (FBG) levels. However, the role of Dyrk1b in glucose metabolism is not…”
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IRX3 Promotes the Browning of White Adipocytes and Its Rare Variants are Associated with Human Obesity Risk
Published in EBioMedicine (01-10-2017)“…IRX3 was recently reported as the effector of the FTO variants. We aimed to test IRX3's roles in the browning program and to evaluate the association between…”
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Can the combination of time-lapse parameters and clinical features predict embryonic ploidy status or implantation?
Published in Reproductive biomedicine online (01-10-2022)“…•A novel model is capable of selecting the most competent euploid blastocysts.•Validating ploidy status cannot be predicted using time-lapse…”
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Pancreatic necrosis volume is closely associated with late-onset vascular complications after discharge in necrotizing pancreatitis
Published in European journal of radiology (01-11-2024)“…To explore the incidence, dynamic changes, prognostic factors and prognosis of late-onset vascular complications after discharge in patients with necrotizing…”
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Association of a gain‐of‐function variant in LGR4 with central obesity
Published in Obesity (Silver Spring, Md.) (01-01-2017)“…Objective To determine the relationship of the gain‐of‐function variant A750T in leucine‐rich repeat containing G protein‐coupled receptor 4 (LGR4) with…”
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Recurrence for patients with first episode of hypertriglyceridemia-induced acute pancreatitis: A prospective cohort study
Published in Journal of clinical lipidology (01-01-2023)“…•Hypertriglyceridemia-induced acute pancreatitis recurrence rate is high.•High triglyceride (TG) level post attack is closely associated with…”
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Rare Loss-of-Function Variants in NPC1 Predispose to Human Obesity
Published in Diabetes (New York, N.Y.) (01-04-2017)“…Some Shanghai Clinical Center f a role of Niemann-Pick type C1 ( ) for obesity traits. However, whether the loss-of-function mutations in cause adiposity in…”
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Ablation of Lgr4 enhances energy adaptation in skeletal muscle via activation of Ampk/Sirt1/Pgc1α pathway
Published in Biochemical and biophysical research communications (21-08-2015)“…Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is a newfound obese-associated gene. Previous study reveals that heterozygous mutation of…”
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Genetic interaction of DGAT2 and FAAH in the development of human obesity
Published in Endocrine (01-05-2017)“…Purpose DGAT2 is the critical catalyzing enzyme for triglyceride biosynthesis, and excess triglyceride accumulation in fat tissues is a fundamental process for…”
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