Search Results - "Zou, Sailan"
-
1
Targeting STAT3 in Cancer Immunotherapy
Published in Molecular cancer (24-09-2020)“…Abstract As a point of convergence for numerous oncogenic signaling pathways, signal transducer and activator of transcription 3 (STAT3) is central in…”
Get full text
Journal Article -
2
Targeting RNA G-quadruplex with repurposed drugs blocks SARS-CoV-2 entry
Published in PLoS pathogens (01-01-2023)“…The rapid emergence of SARS-CoV-2 variants of concern, the complexity of infection, and the functional redundancy of host factors, underscore an urgent need…”
Get full text
Journal Article -
3
A miRNA-mediated attenuation of hepatocarcinogenesis in both hepatocytes and Kupffer cells
Published in Molecular therapy. Nucleic acids (13-12-2022)“…MicroRNAs (miRNAs) are small noncoding RNAs that regulate a variety of physiological and pathological functions. miR-26a is one of the many miRNAs that have…”
Get full text
Journal Article -
4
Enhanced nuclear translation is associated with proliferation and progression across multiple cancers
Published in MedComm (2020) (01-06-2023)“…Recent technological advances have re‐invigorated the interest in nuclear translation (NT), but the underlying mechanisms and functional implications of NT…”
Get full text
Journal Article -
5
The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation
Published in Molecular metabolism (Germany) (01-05-2019)“…The mixed lineage kinase domain like (MLKL) protein, receptor interacting protein (RIPK) 1, and RIPK3 are key regulators of necroptosis, a highly…”
Get full text
Journal Article -
6
On Energy Optimization for Hierarchical Federated Learning With Delay Constraint Through Node Cooperation
Published in IEEE internet of things journal (01-05-2024)“…In hierarchical federated learning (HFL), edge computing is introduced for partial model aggregation to reduce latency. High energy cost is an important issue…”
Get full text
Journal Article -
7
Extrachromosomal circular MiR-17-92 amplicon promotes HCC
Published in Hepatology (Baltimore, Md.) (01-01-2024)“…Extrachromosomal circular DNAs (eccDNAs) are prevalent in cancer genomes and emerge as a class of crucial yet less characterized oncogenic drivers. However,…”
Get full text
Journal Article -
8
An Endoplasmic Reticulum Stress–MicroRNA‐26a Feedback Circuit in NAFLD
Published in Hepatology (Baltimore, Md.) (01-04-2021)“…Background and Aims Endoplasmic reticulum (ER) stress is an adaptive response to excessive ER demand and contributes to the development of numerous diseases,…”
Get full text
Journal Article -
9
RNA G-quadruplex regulates microRNA-26a biogenesis and function
Published in Journal of hepatology (01-08-2020)“…RNA G-quadruplexes (RG4s) appear to be important in post-transcriptional gene regulation, but their pathophysiological functions remain unknown. MicroRNA-26a…”
Get full text
Journal Article -
10
UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination
Published in Oncogene (25-11-2022)“…Cancer cells rely on heightened protein quality control mechanisms, including the ubiquitin-proteosome system that is predominantly driven by ubiquitination…”
Get full text
Journal Article -
11
Circular RNA circDVL1 inhibits clear cell renal cell carcinoma progression through the miR-412-3p/PCDH7 axis
Published in International journal of biological sciences (2022)“…Clear cell renal cell carcinoma (ccRCC) is a primary kidney cancer with high aggressive phenotype and extremely poor prognosis. Accumulating evidence suggests…”
Get full text
Journal Article -
12
A microRNA checkpoint for Ca2+ signaling and overload in acute pancreatitis
Published in Molecular therapy (06-04-2022)“…Acute pancreatitis (AP) is a common digestive disease without specific treatment, and its pathogenesis features multiple deleterious amplification loops…”
Get full text
Journal Article -
13
A microRNA checkpoint for Ca 2+ signaling and overload in acute pancreatitis
Published in Molecular therapy (06-04-2022)“…Acute pancreatitis (AP) is a common digestive disease without specific treatment, and its pathogenesis features multiple deleterious amplification loops…”
Get full text
Journal Article -
14
Energy-Efficient Online Node Cooperation Strategy for Hierarchical Federated Learning
Published in 2022 IEEE Smartworld, Ubiquitous Intelligence & Computing, Scalable Computing & Communications, Digital Twin, Privacy Computing, Metaverse, Autonomous & Trusted Vehicles (SmartWorld/UIC/ScalCom/DigitalTwin/PriComp/Meta) (01-12-2022)“…With the popularity of Internet of Things (IoT), a large amount of data is generated at the network edge. Federated Learning (FL) can use this data for joint…”
Get full text
Conference Proceeding