Search Results - "Zou, Rongfeng"

Peptide self-assembly triggered by metal ions by Zou, Rongfeng, Wang, Qi, Wu, Junchen, Wu, Jingxian, Schmuck, Carsten, Tian, He

“…Through their unique and specific interactions with various metal ions, naturally occurring proteins control structures and functions of many biological…”
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Molecular Engineered Squaraine Nanoprobe for NIR-II/Photoacoustic Imaging and Photothermal Therapy of Metastatic Breast Cancer by Yao, Defan, Wang, Yanshu, Zou, Rongfeng, Bian, Kexin, Liu, Pei, Shen, Shuzhan, Yang, Weitao, Zhang, Bingbo, Wang, Dengbin

“…Various squaraine dyes have been developed for biological imaging. Nevertheless, squaraine dyes with emission in the second window (NIR-II, 1000–1700 nm) have…”
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Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers by Zhang, Yingyi, Dijkman, Patricia M., Zou, Rongfeng, Zandl-Lang, Martina, Sanchez, Ricardo M., Eckhardt-Strelau, Luise, Köfeler, Harald, Vogel, Horst, Yuan, Shuguang, Kudryashev, Mikhail

“…Pentameric ligand-gated ion channels (pLGICs) of the Cys-loop receptor family are key players in fast signal transduction throughout the nervous system. They…”
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Secondary-structure switch regulates the substrate binding of a YopJ family acetyltransferase by Xia, Yao, Zou, Rongfeng, Escouboué, Maxime, Zhong, Liang, Zhu, Chengjun, Pouzet, Cécile, Wu, Xueqiang, Wang, Yongjin, Lv, Guohua, Zhou, Haibo, Sun, Pinghua, Ding, Ke, Deslandes, Laurent, Yuan, Shuguang, Zhang, Zhi-Min

“…The Yersinia outer protein J (YopJ) family effectors are widely deployed through the type III secretion system by both plant and animal pathogens. As…”
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Structural insights into drug transport by an aquaglyceroporin by Chen, Wanbiao, Zou, Rongfeng, Mei, Yi, Li, Jiawei, Xuan, Yumi, Cui, Bing, Zou, Junjie, Wang, Juncheng, Lin, Shaoquan, Zhang, Zhe, Wang, Chongyuan

“…Pentamidine and melarsoprol are primary drugs used to treat the lethal human sleeping sickness caused by the parasite Trypanosoma brucei . Cross-resistance to…”
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MolADI: A Web Server for Automatic Analysis of Protein–Small Molecule Dynamic Interactions by Bai, Bing, Zou, Rongfeng, Chan, H. C. Stephen, Li, Hongchun, Yuan, Shuguang

“…Protein–ligand interaction analysis is important for drug discovery and rational protein design. The existing online tools adopt only a single conformation of…”
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Rutin, A Natural Inhibitor of IGPD Protein, Partially Inhibits Biofilm Formation in Staphylococcus xylosus ATCC700404 in vitro and in vivo by Qu, Qianwei, Cui, Wenqiang, Xing, Xiaoxu, Zou, Rongfeng, Huang, Xingyu, Wang, Xiaozhen, Wu, Tong, Bello-Onaghise, God'spower, Yuan, Shuguang, Li, Yanhua

“…( ) has become an emerging opportunistic pathogen due to its strong biofilm formation ability. Simultaneously, the biofilm of bacteria plays an important role…”
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Corrigendum to “discovery of traditional Chinese medicines against porcine reproductive and respiratory syndrome virus” [Pharmacological Research - Modern Chinese Medicine 1 (2021) 100003] by Cui, Wenqiang, Yu, Fei, Zhang, Yuefeng, Han, Xiao, Zou, Rongfeng, Tang, Yandong, Wang, Linguang, Eliphaz, Nsabimana, Wang, Jian, Yuan, Shuguang, Cai, Xuehui, Li, Yanhua

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Discovery of traditional Chinese medicines against porcine reproductive and respiratory syndrome virus by Cui, Wenqiang, Yu, Fei, Zhang, Yuefeng, Han, Xiao, Zou, Rongfeng, Tang, Yandong, Wang, Linguang, Eliphaz, Nsabimana, Wang, Jian, Yuan, Shuguang, Cai, Xuehui, Li, Yanhua

“…•We creatively used computer simulations to identify potential virus-cell binding sites.•A salt bridge between Arg561 and Asp505 was important to stabilize the…”
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Wavelength-adjustable butterfly molecules in dynamic nanoassemblies for Extradomain-B fibronectin-modulating optical imaging and synchronous phototherapy of triple-negative breast cancer by Yao, Defan, Wang, Yanshu, Zou, Rongfeng, Bian, Kexin, Yuan, Shuguang, Zhang, Bingbo, Wang, Dengbin

“…[Display omitted] •Wavelength-adjustable butterfly molecules were assembled in dynamic nanoassemblies.•The nanoassemblies could selectively target and image…”
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Activity of Antimicrobial Peptide Aggregates Decreases with Increased Cell Membrane Embedding Free Energy Cost by Zou, Rongfeng, Zhu, Xiaomin, Tu, Yaoquan, Wu, Junchen, Landry, Markita P

“…Antimicrobial peptides (AMPs) are a promising alternative to antibiotics for mitigating bacterial infections, in light of increasing bacterial resistance to…”
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Dynamics with Explicit Solvation Reveals Formation of the Prereactive Dimer as Sole Determining Factor for the Efficiency of Ru(bda)L2 Catalysts by Zhan, Shaoqi, Zou, Rongfeng, Ahlquist, Mårten S. G

“…This report describes all key steps in the O–O bond formation from two separated [RuVO­(bda)­L2]+ cations to form the dinuclear…”
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Free Energy Profile and Kinetics of Coupled Folding and Binding of the Intrinsically Disordered Protein p53 with MDM2 by Zou, Rongfeng, Zhou, Yang, Wang, Yong, Kuang, Guanglin, Ågren, Hans, Wu, Junchen, Tu, Yaoquan

“…Intrinsically disordered proteins (IDPs) exert their functions by binding to partner proteins via a complex process that includes coupled folding and binding…”
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Molecular basis of ligand selectivity for melatonin receptors by Cui, Wenqiang, Dong, Junlin, Wang, Shiyu, Vogel, Horst, Zou, Rongfeng, Yuan, Shuguang

“…Sleep disorders in adults are related to adverse health effects such as reduced quality of life and increased mortality. About 30-40% of adults are suffering…”
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Dynamics with Explicit Solvation Reveals Formation of the Prereactive Dimer as Sole Determining Factor for the Efficiency of Ru(bda)L 2 Catalysts by Zhan, Shaoqi, Zou, Rongfeng, Ahlquist, Mårten S. G.

“…This report describes all key steps in the O-O bond formation from two separated [Ru-V=O(bda)L-2](+) cations to form the dinuclear…”
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Magainin II modified polydiacetylene micelles for cancer therapy by Yang, Danling, Zou, Rongfeng, Zhu, Yu, Liu, Ben, Yao, Defan, Jiang, Juanjuan, Wu, Junchen, Tian, He

“…Polydiacetylene (PDA) micelles have been widely used to deliver anticancer drugs in the treatment of a variety of tumours and for imaging living cells. In this…”
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Hit Identification Driven by Combining Artificial Intelligence and Computational Chemistry Methods: A PI5P4K‑β Case Study by Wei, Lin, Xu, Min, Liu, Zhiqiang, Jiang, Chongguo, Lin, Xiaohua, Hu, Yaogang, Wen, Xiaoming, Zou, Rongfeng, Peng, Chunwang, Lin, Hongrui, Wang, Guo, Yang, Lijun, Fang, Lei, Yang, Mingjun, Zhang, Peiyu

“…Computer-aided drug design (CADD), especially artificial intelligence-driven drug design (AIDD), is increasingly used in drug discovery. In this paper, a novel…”
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The role of metal ions in G protein‐coupled receptor signalling and drug discovery by Zou, Rongfeng, Wang, Xueying, Li, Shu, Chan, H. C. Stephen, Vogel, Horst, Yuan, Shuguang

“…Metal ions, such as Na+, Mg2+, Ca2+, and Zn2+, are highly abundant in biological systems. For many G protein‐coupled receptors (GPCRs), metal ions, especially…”
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A Probe for the Detection of Hypoxic Cancer Cells by Luo, Shenzheng, Zou, Rongfeng, Wu, Junchen, Landry, Markita P

“…Hypoxia is a common feature of tumor cells. Nitroreductase (NTR), a common biomarker of hypoxia, has been widely used to evaluate the extent of tumor hypoxia…”
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Synergistic application of molecular docking and machine learning for improved binding pose by Li Yaqi, Lin Hongrui, Yang He, Yuan Yannan, Zou Rongfeng, Zhou Gengmo, Zheng Hang

“…Accurate prediction of protein-ligand complex structures is a crucial step in structure-based drug design. Traditional molecular docking methods exhibit…”
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