Search Results - "Zou, Liangxing"

Interleukin‐1 Trap Rilonacept Improved Health‐Related Quality of Life and Sleep in Patients With Recurrent Pericarditis: Results From the Phase 3 Clinical Trial RHAPSODY by Brucato, Antonio, Lim‐Watson, Michelle Z., Klein, Allan, Imazio, Massimo, Cella, David, Cremer, Paul, LeWinter, Martin M., Luis, Sushil Allen, Lin, David, Lotan, Dor, Pancrazi, Massimo, Trotta, Lucia, Klooster, Brittany, Litcher‐Kelly, Leighann, Zou, Liangxing, Magestro, Matt, Wheeler, Alistair, Paolini, John F., Abbate, Antonio, Abo‐Auda, Wael, Akhtar, Asif, Arad, Michael, Atar, Shaul, Baibhav, Bipul, Bhalla, Karan, Brucato, Antonio, Collins, Sean, Colquhoun, David, Cremer, Paul, Cross, David, Dwivedi, Girish, Eisen, Alon, Freedberg, Nahum, Fuchs, Shmuel, Gaddam, Eliyazar, Gattorno, Marco, Gelfand, Eli, Grena, Paul, Halabi, Majdi, Harris, David, Imazio, Massimo, Insalaco, Antonella, Karim, Amin, Klein, Allan, Knowlton, Kirk, Kontzias, Apostolos, Kornberg, Robert, Latif, Faisal, Leibowitz, David, LeWinter, Martin, Lin, David, Lotan, Dor

“…Background Recurrent pericarditis is characterized by painful flares and inflammation, which negatively impact health‐related quality of life. RHAPSODY…”
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NEUTROPHIL TO LYMPHOCYTE RATIO FOR TRACKING INFLAMMATION AND RECURRENCE IN PATIENTS WITH RECURRENT PERICARDITIS: POST HOC ASSESSMENT OF A PHASE 3 TRIAL, RHAPSODY by Cremer, Paul, Wheeler, Alistair, Zou, Liangxing, Fang, Fang, Abadie, Bryan, Saef, Joshua, Imazio, Massimo, Klein, Allan L., Paolini, John Frank

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Peak study: A phase 3, randomized, open-label multicenter clinical study of bezuclastinib (CGT9486) and sunitinib in combination versus sunitinib in patients with gastrointestinal stromal tumors (GIST) by Heinrich, Michael C., Somaiah, Neeta, Trent, Jonathan C., Wilky, Breelyn A., Burgess, Melissa Amber, Singh, Arun S., Attia, Steven, Agulnik, Mark, Tap, William D., Bauer, Sebastian, Jones, Robin Lewis, Serrano, Cesar, Zou, Liangxing, Moynihan, Kevin, Lawrence, Julia, Wagner, Andrew J.

“…TPS766 Background: Imatinib is the worldwide standard for first-line therapy of advanced KIT-mutant GIST. However, secondary resistance mutations in the KIT…”
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Abstract 12057: Absence of Pericarditis Recurrence in Rilonacept-Treated Patients With COVID-19 and mRNA Vaccinations: Experience From Phase 3 Rhapsody Long-Term Extension by brucato, antonio, Trotta, Lucia, Arad, Michael, Cremer, Paul C, Gaddam, Eliyazar, Insalaco, Antonella, Klutstein, Marc W, Lewinter, Martin M, Lin, David, Luis, Sushil A, Wasserstrum, Yishay, Plummer, Emily, Samant, Manoj, Zou, Liangxing, Klein, Allan L, Imazio, Massimo, Paolini, John F

“…IntroductionRare cardiac complications of COVID-19 and COVID-19 mRNA vaccination include pericarditis and myocarditis. Patients with recurrent pericarditis may…”
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Transition to rilonacept monotherapy from oral therapies in patients with recurrent pericarditis by Brucato, Antonio, Wheeler, Alistair, Luis, Sushil Allen, Abbate, Antonio, Cremer, Paul C, Zou, Liangxing, Insalaco, Antonella, Lewinter, Martin, Lewis, Basil S, Lin, David, Nicholls, Stephen, Pancrazi, Massimo, Klein, Allan L, Imazio, Massimo, Paolini, John F

“…Polypharmacy management of recurrent pericarditis (RP) often involves long-term therapies, often with negative effects. Slow tapering of oral therapies is…”
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Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double-blind, placebo-controlled, phase 2a study by Sofen, Howard, Bissonnette, Robert, Yosipovitch, Gil, Silverberg, Jonathan I., Tyring, Stephen, Loo, Wei Jing, Zook, Matthew, Lee, Mark, Zou, Liangxing, Jiang, Guang-Liang, Paolini, John F.

“…Prurigo nodularis is a chronic skin disease characterised by intensely pruritic, hyperkeratotic nodules. Vixarelimab, a human monoclonal antibody, binds to the…”
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Safety, pharmacokinetics (PK), and clinical activity of bezuclastinib + sunitinib in previously-treated gastrointestinal stromal tumor (GIST): Results from part 1 of the phase 3 Peak study by Tap, William D., Wagner, Andrew J., Bauer, Sebastian, Heinrich, Michael C., Jones, Robin Lewis, Serrano, Cesar, von Mehren, Margaret, Somaiah, Neeta, Andor, Tom, Zou, Liangxing, Exter, Ben, Lawrence, Julia, LaHaie, Celeste, Mitchell, Shaunica, Moynihan, Kevin, Sachs, Jessica, Sun, Lei, Trent, Jonathan C.

“…11537 Background: Patients with GIST often relapse after first line therapy with imatinib due to secondary resistance mutations in KIT. As the KIT mutation…”
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Abstract 11653: Prolonged Rilonacept Treatment in Rhapsody Long-Term Extension Provided Persistent Reduction of Pericarditis Recurrence Risk by Imazio, Massimo, Klein, Allan L, Abbate, Antonio, Arad, Michael, brucato, antonio, Cremer, Paul C, Gaddam, Eliyazar, Insalaco, Antonella, Lewinter, Martin M, Lewis, Basil, Lin, David, Luis, Sushil A, Nicholls, Stephen J, Sutej, Paul, Wasserstrum, Yishay, Samant, Manoj, Zou, Liangxing, Fang, Fang, Paolini, John F

“…IntroductionRilonacept reduced pericarditis recurrence in the phase 3 trial RHAPSODY. The long-term extension (LTE) enabled further insights into efficacy,…”
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Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double-blind, placebo-controlled, phase 2a studyResearch in context by Howard Sofen, Robert Bissonnette, Gil Yosipovitch, Jonathan I. Silverberg, Stephen Tyring, Wei Jing Loo, Matthew Zook, Mark Lee, Liangxing Zou, Guang-Liang Jiang, John F. Paolini

“…Background: Prurigo nodularis is a chronic skin disease characterised by intensely pruritic, hyperkeratotic nodules. Vixarelimab, a human monoclonal antibody,…”
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Aperture-Shared Base Station Antenna Array With Low Scattering Interference by Zou, Liangxing, Chu, Qing-Xin

“…An interleaved dual-band dual-polarized apertureshared antenna, with antennas operating at 1.7-2.8GHz (lowerband, LB) and 3.3-3.8GHz (higher-band, HB), is…”
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C-Cbl Regulates Neutrophil Integrin-dependent Respiratory Burst (135.67) by Peterson, Erik J, Zou, Liangxing, Ellingson, Sonja

“…Abstract Signaling through integrin receptors is required for optimal reactive oxygen species (ROS) production by polymorphonuclear neutrophils (PMN). The E3…”
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A Dual-Band Aperture-Shaped Antenna Array Based on Choke Stubs by Meng, Zhixi, Zou, Liangxing, Tu, Zhihong, Chu, Qing-Xin

“…A dual-band aperture-shared antenna is designed, with the low-band (LB) antenna operating at 1.7-2.2 GHz and the high-band (HB) antennas operating at 3.3-3.8…”
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Defective positive selection results in T cell lymphopenia and increased autoimmune diabetes in ADAP deficient BDC2.5-Bl/6 mice by Zou, Liangxing, Mendez, Felipe, Martin-Orozco, Natalia, Peterson, Erik J.

“…Adhesion and Degranulation Promoting Adapter protein (ADAP), a positive regulator of T cell receptor (TCR) signaling, is required for thymocyte development and…”
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Defective positive selection results in T cell lymphopenia and increased autoimmune diabetes in ADAP-deficient BDC2.5-C57BL/6 mice by Zou, Liangxing, Mendez, Felipe, Martin-Orozco, Natalia, Peterson, Erik J

“…Adhesion and degranulation promoting adapter protein (ADAP), a positive regulator of T cell receptor (TCR) signaling, is required for thymocyte development and…”
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Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis by Dluzniewska, Joanna, Zou, Liangxing, Harmon, Ian R, Ellingson, Marc T, Peterson, Erik J

“…Adhesion- and degranulation-promoting adaptor protein (ADAP) modulates T cell development and function and promotes TCR signaling. Regulation of ADAP protein…”
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Regulation of autoimmunity and integrin signaling by adaptor proteins ADAP, PRAM-1 and c-Cbl by Zou, Liangxing

“…To increase our understanding of adaptor proteins in immune responses, we investigated the roles of adaptor protein ADAP in autoimmune diabetes, and PRAM-1 and…”
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Pericardial late gadolinium enhancement and time to recurrence: a substudy from RHAPSODY, a phase 3 clinical trial of rilonacept in recurrent pericarditis by Cremer, Paul C, Lin, David, Luis, Sushil A, Petersen, John, Abbate, Antonio, Jellis, Christine L, Kwon, Debbie, Brucato, Antonio, Fang, Fang, Insalaco, Antonella, LeWinter, Martin, Lewis, Basil S, Zou, Liangxing, Nicholls, Stephen J, Klein, Allan L, Imazio, Massimo, Paolini, John F

“…In this protocol-predefined substudy of the RHAPSODY trial, the primary aim was to assess whether pericardial late gadolinium enhancement (LGE) was associated…”
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